World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
79
Citations
18141
World Ranking
17748
National Ranking
203

Overview

Wen Tan is affiliated with Peking Union Medical College Hospital in China and has contributed extensively to research in medicine, biochemistry, genetics, and molecular biology. Their work spans multiple subfields with strong emphasis on molecular biology, oncology, surgery, immunology, and cancer research.

Their research topics focus on several key areas related to cancer biology, including:

  • Esophageal cancer research and treatment
  • Pancreatic and hepatic oncology research
  • Cancer immunotherapy and biomarkers
  • Immune cells in cancer
  • Cancer-related gene regulation
  • RNA modifications and cancer
  • Single-cell and spatial transcriptomics

Wen Tan has published in a variety of scientific journals, with frequent contributions to:

  • Nature Communications
  • Signal Transduction and Targeted Therapy
  • PubMed
  • Theranostics
  • Cancer Biology and Medicine

Their recent papers include:

  • Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis, 2021, Nature Communications
  • Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer, 2020, Nature Communications
  • Serum piRNA-54265 is a New Biomarker for early detection and clinical surveillance of Human Colorectal Cancer, 2020, Theranostics
  • Metformin inhibits pancreatic cancer metastasis caused by SMAD4 deficiency and consequent HNF4G upregulation, 2020, Protein & Cell
  • Harnessing the tumor microenvironment: targeted cancer therapies through modulation of epithelial-mesenchymal transition, 2025, Journal of Hematology & Oncology

Wen Tan frequently collaborates with several co-authors who have contributed to their scientific output. These co-authors include:

  • Dongxin Lin
  • Chen Wu
  • Yiyi Xi
  • Shaosen Zhang
  • Wenjia Guo

Best Publications

  • Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis.

    Jian Xu;Chen Wu;Xu Che;Li Wang

  • A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese

    Zhibin Hu;Chen Wu;Yongyong Shi;Huan Guo

  • Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

    Qing Lan;Chao A. Hsiung;Keitaro Matsuo;Yun Chul Hong

  • Methylenetetrahydrofolate reductase polymorphisms increase risk of esophageal squamous cell carcinoma in a Chinese population.

    Chunying Song;Deyin Xing;Wen Tan;Qingyi Wei

  • Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations

    Chen Wu;Zhibin Hu;Zhonghu He;Weihua Jia

  • Identification of Functional Genetic Variants in Cyclooxygenase-2 and Their Association With Risk of Esophageal Cancer

    Xuemei Zhang;Xuemei Zhang;Xiaoping Miao;Wen Tan;Baitang Ning

  • A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers.

    Tong Sun;Yang Gao;Wen Tan;Sufang Ma

  • Excessive miR-25-3p maturation via N 6 -methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression

    Jialiang Zhang;Ruihong Bai;Mei Li;Huilin Ye

  • Identification of genetic variants in base excision repair pathway and their associations with risk of esophageal squamous cell carcinoma.

    Bingtao Hao;Haijian Wang;Kaixin Zhou;Yi Li

  • A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1

    Yongyong Shi;Zhibin Hu;Chen Wu;Juncheng Dai

  • Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

    Chen Wu;Chen Wu;Peter Kraft;Kan Zhai;Jiang Chang

  • Polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma.

    Tong Sun;Xiaoping Miao;Xuemei Zhang;Wen Tan

  • Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation

    Jian Zheng;Xudong Huang;Wen Tan;Dianke Yu

  • Functional Haplotypes in the Promoter of Matrix Metalloproteinase-2 Predict Risk of the Occurrence and Metastasis of Esophageal Cancer

    Chunyuan Yu;Yifeng Zhou;Xiaoping Miao;Ping Xiong

  • Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer.

    Xuemei Zhang;Xiaoping Miao;Gang Liang;Bingtao Hao;Bingtao Hao

  • CYP 1A1 polymorphism and risk of lung cancer in relation to tobacco smoking: a case-control study in China.

    Nan Song;Wen Tan;Deyin Xing;Dongxin Lin

  • The Role of P53 and MDM2 Polymorphisms in the Risk of Esophageal Squamous Cell Carcinoma

    Yuan Hong;Xiaoping Miao;Xuemei Zhang;Fang Ding

  • Impact of Genetic Polymorphisms in Cytochrome P450 2E1 and Glutathione S-Transferases M1, T1, and P1 on Susceptibility to Esophageal Cancer among High-Risk Individuals in China

    Wen Tan;Nan Song;Gui Qi Wang;Qing Liu

  • Genetic Polymorphisms in Cell Cycle Regulatory Genes MDM2 and TP53 Are Associated With Susceptibility to Lung Cancer

    Xuemei Zhang;Xiaoping Miao;Yongli Guo;Wen Tan

  • The 5p15.33 Locus Is Associated with Risk of Lung Adenocarcinoma in Never-Smoking Females in Asia

    Chao Agnes Hsiung;Qing Lan;Yun Chul Hong;Chien Jen Chen;Chien Jen Chen

Frequent Co-Authors

Dongxin Lin
Dongxin Lin Chinese Academy of Sciences
Chen Wu
Chen Wu Peking Union Medical College Hospital
Xiaoping Miao
Xiaoping Miao Huazhong University of Science and Technology
Jiang Chang
Jiang Chang University of Chinese Academy of Sciences
Zhibin Hu
Zhibin Hu Nanjing Medical University
Hongbing Shen
Hongbing Shen Nanjing Medical University
Stephen J. Chanock
Stephen J. Chanock National Institutes of Health
Daru Lu
Daru Lu Fudan University
Meredith Yeager
Meredith Yeager Hood College
Jianjun Liu
Jianjun Liu Genome Institute of Singapore

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