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Biology and Biochemistry

D-Index
69
Citations
15238
World Ranking
7486
National Ranking
240

Overview

Chen Wu is affiliated with Peking Union Medical College Hospital in China. Their research spans broadly within the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on subfields such as Molecular Biology, Oncology, Cancer Research, Health, Toxicology and Mutagenesis, and Surgery.

The main topics investigated by Chen Wu include:

  • Air Quality and Health Impacts
  • Cancer Genomics and Diagnostics
  • Climate Change and Health Impacts
  • Single-cell and spatial transcriptomics
  • RNA modifications and cancer
  • Esophageal Cancer Research and Treatment
  • Pancreatic and Hepatic Oncology Research

Chen Wu's recent publications reflect a focus on cancer biology and molecular mechanisms underpinning tumorigenesis, as well as clinical studies related to oncology. Notable papers authored or coauthored by Chen Wu include:

  • "Tumor initiation and early tumorigenesis: molecular mechanisms and interventional targets," 2024, Signal Transduction and Targeted Therapy
  • "Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis," 2021, Nature Communications
  • "DNMT1-mediated methylation of BEX1 regulates stemness and tumorigenicity in liver cancer," 2021, Journal of Hepatology
  • "Efficacy and safety of camrelizumab plus apatinib during the perioperative period in resectable hepatocellular carcinoma: a single-arm, open label, phase II clinical trial," 2022, Journal for ImmunoTherapy of Cancer
  • "2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS," 2020, Endocrine

The research venues where Chen Wu frequently publishes include:

  • The Science of The Total Environment
  • Nature Communications
  • Signal Transduction and Targeted Therapy
  • Research Square (Research Square)
  • Cancer Cell

Throughout their career, Chen Wu has collaborated regularly with several coauthors, with notable repeated partnerships including:

  • Dongxin Lin
  • Tong Zhu
  • Yiqun Han
  • Wen Tan
  • Xi Chen

Best Publications

  • Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis.

    Jian Xu;Chen Wu;Xu Che;Li Wang

  • Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development

    Jared R Mayers;Chen Wu;Chen Wu;Clary B Clish;Peter Kraft

  • A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese

    Zhibin Hu;Chen Wu;Yongyong Shi;Huan Guo

  • Genome-wide association study identifies 1p36.22 as a new susceptibility locus for hepatocellular carcinoma in chronic hepatitis B virus carriers

    Hongxing Zhang;Yun Zhai;Zhibin Hu;Chen Wu

  • Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

    Qing Lan;Chao A. Hsiung;Keitaro Matsuo;Yun Chul Hong

  • Genetic variants in STAT4 and HLA-DQ genes confer risk of hepatitis B virus-related hepatocellular carcinoma

    De Ke Jiang;Jielin Sun;Guangwen Cao;Yao Liu

  • Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer

    Brian M. Wolpin;Cosmeri Rizzato;Peter Kraft;Charles Kooperberg

  • Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations

    Chen Wu;Zhibin Hu;Zhonghu He;Weihua Jia

  • Excessive miR-25-3p maturation via N 6 -methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression

    Jialiang Zhang;Ruihong Bai;Mei Li;Huilin Ye

  • A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1

    Yongyong Shi;Zhibin Hu;Chen Wu;Juncheng Dai

  • Genome-wide association analyses of esophageal squamous cell carcinoma in Chinese identify multiple susceptibility loci and gene-environment interactions

    Chen Wu;Chen Wu;Peter Kraft;Kan Zhai;Jiang Chang

  • Pancreatic cancer risk variant in LINC00673 creates a miR-1231 binding site and interferes with PTPN11 degradation

    Jian Zheng;Xudong Huang;Wen Tan;Dianke Yu

  • Reproducibility of metabolomic profiles among men and women in 2 large cohort studies.

    Mary K. Townsend;Clary B. Clish;Peter Kraft;Chen Wu

  • Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations

    Chen Wu;Xiaoping Miao;Liming Huang;Xu Che

  • Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

    Wanqing Wen;Wei Zheng;Yukinori Okada;Fumihiko Takeuchi

  • The 5p15.33 Locus Is Associated with Risk of Lung Adenocarcinoma in Never-Smoking Females in Asia

    Chao Agnes Hsiung;Qing Lan;Yun Chul Hong;Chien Jen Chen;Chien Jen Chen

  • Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations.

    Jiang Chang;Wenle Tan;Zhiqiang Ling;Ruibin Xi

  • Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations.

    Juncheng Dai;Jun Lv;Meng Zhu;Yuzhuo Wang

  • An estrogen receptor α suppressor, microRNA-22, is downregulated in estrogen receptor α-positive human breast cancer cell lines and clinical samples

    Jianhua Xiong;Dianke Yu;Na Wei;Hanjiang Fu

  • Dissecting esophageal squamous-cell carcinoma ecosystem by single-cell transcriptomic analysis.

    Xiannian Zhang;Linna Peng;Yingying Luo;Shaosen Zhang

Frequent Co-Authors

Dongxin Lin
Dongxin Lin Chinese Academy of Sciences
Wen Tan
Wen Tan Peking Union Medical College Hospital
Hongbing Shen
Hongbing Shen Nanjing Medical University
Jiang Chang
Jiang Chang University of Chinese Academy of Sciences
Zhibin Hu
Zhibin Hu Nanjing Medical University
Xiaoping Miao
Xiaoping Miao Huazhong University of Science and Technology
Stephen J. Chanock
Stephen J. Chanock National Institutes of Health
Xiao-Ou Shu
Xiao-Ou Shu Vanderbilt University Medical Center
Wei Zheng
Wei Zheng Vanderbilt University Medical Center
Guangfu Jin
Guangfu Jin Nanjing Medical University

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