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Genetics

D-Index
71
Citations
16392
World Ranking
2209
National Ranking
59

Overview

Daru Lu is affiliated with Fudan University in China and has a significant research presence in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work spans numerous subfields including Molecular Biology, Genetics, Pediatrics, Perinatology and Child Health, Infectious Diseases, and Cancer Research.

The scientist's research topics cover a variety of areas such as Prenatal Screening and Diagnostics, CRISPR and Genetic Engineering, Hemoglobinopathies and Related Disorders, Genomic Variations and Chromosomal Abnormalities, Cancer Genomics and Diagnostics, RNA Modifications and Cancer, and Genetic Syndromes and Imprinting.

Recent publications by Daru Lu include the following papers:

  • Subchronic exposure to concentrated ambient PM2.5 perturbs gut and lung microbiota as well as metabolic profiles in mice, 2020, Environmental Pollution
  • Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials, 2023, Nature Biotechnology
  • FOSL1 promotes proneural-to-mesenchymal transition of glioblastoma stem cells via UBC9/CYLD/NF-κB axis, 2022, Molecular Therapy
  • Discovery and engineering of small SlugCas9 with broad targeting range and high specificity and activity, 2021, Nucleic Acids Research
  • A highly specific CRISPR-Cas12j nuclease enables allele-specific genome editing, 2023, Science Advances

They frequently collaborate with a group of co-authors including H. J. Yang, Chenming Xu, Hongyan Chen, Caixia Lei, and Songchang Chen.

Daru Lu's work is regularly published in venues such as PubMed, Journal of Human Genetics, International Journal of Molecular Sciences, bioRxiv (Cold Spring Harbor Laboratory), and Clinical and Translational Medicine.

Best Publications

  • Y-Chromosome Evidence for a Northward Migration of Modern Humans into Eastern Asia during the Last Ice Age

    Bing Su;Junhua Xiao;Peter Underhill;Ranjan Deka

  • Genetic evidence supports demic diffusion of Han culture

    Bo Wen;Hui Li;Daru Lu;Xiufeng Song

  • A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese

    Zhibin Hu;Chen Wu;Yongyong Shi;Huan Guo

  • Redox/pH dual stimuli-responsive biodegradable nanohydrogels with varying responses to dithiothreitol and glutathione for controlled drug release

    Yuan-Jia Pan;Yuan-Yuan Chen;Dong-Rui Wang;Chuan Wei

  • Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

    Qing Lan;Chao A. Hsiung;Keitaro Matsuo;Yun Chul Hong

  • Y chromosome haplotypes reveal prehistorical migrations to the Himalayas.

    Bing Su;Chunjie Xiao;Chunjie Xiao;Ranjan Deka;Mark T. Seielstad

  • African origin of modern humans in East Asia: a tale of 12,000 Y chromosomes.

    Yuehai Ke;Bing Su;Bing Su;Bing Su;Xiufeng Song;Daru Lu

  • Intrinsic BET inhibitor resistance in SPOP -mutated prostate cancer is mediated by BET protein stabilization and AKT–mTORC1 activation

    Pingzhao Zhang;Dejie Wang;Yu Zhao;Shancheng Ren

  • The RNA-binding protein QKI suppresses cancer-associated aberrant splicing.

    Feng-Yang Zong;Xing Fu;Wen-Juan Wei;Ya-Ge Luo

  • Analyses of genetic structure of Tibeto-Burman populations reveals sex-biased admixture in southern Tibeto-Burmans

    Bo Wen;Xuanhua Xie;Song Gao;Hui Li

  • Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin

    Yifeng Li;Dandan Zhang;Wei Jin;Chunhong Shao

  • Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma.

    Zheng Jiang;Xingang Li;Jin Hu;Wei Zhou

  • Genome-wide association study in Chinese men identifies two new prostate cancer risk loci at 9q31.2 and 19q13.4

    Jianfeng Xu;Zengnan Mo;Dingwei Ye;Meilin Wang

  • Time-Dependent Photoluminescence Blue Shift of the Quantum Dots in Living Cells: Effect of Oxidation by Singlet Oxygen

    Yu Zhang;Jia He;Pei-Nan Wang;Ji-Yao Chen

  • Berberine reduces methylation of the MTTP promoter and alleviates fatty liver induced by a high-fat diet in rats

    XinXia Chang;HongMei Yan;Jing Fei;MingHong Jiang

  • Zinc-finger-nucleases mediate specific and efficient excision of HIV-1 proviral DNA from infected and latently infected human T cells

    Xiying Qu;Pengfei Wang;Donglin Ding;Lin Li

  • Analysis of heritability and shared heritability based on genome-wide association studies for thirteen cancer types

    Joshua N. Sampson;William A. Wheeler;Meredith Yeager;Orestis Panagiotou

  • Genetic Variants on Chromosome 15q25 Associated with Lung Cancer Risk in Chinese Populations

    Chen Wu;Zhibin Hu;Dianke Yu;Liming Huang

  • Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

    Jing Dong;Zhibin Hu;Chen Wu;Huan Guo

  • Genetic Structure of Hmong-Mien Speaking Populations in East Asia as Revealed by mtDNA Lineages

    Bo Wen;Hui Li;Song Gao;Xianyun Mao

Frequent Co-Authors

Zhibin Hu
Zhibin Hu Nanjing Medical University
Hongbing Shen
Hongbing Shen Nanjing Medical University
Qingyi Wei
Qingyi Wei Duke University
Guangfu Jin
Guangfu Jin Nanjing Medical University
Wei Huang
Wei Huang Northwestern Polytechnical University
Li Jin
Li Jin Fudan University
Jianfeng Xu
Jianfeng Xu Arkansas State University
Bing Su
Bing Su Chinese Academy of Sciences
Dongxin Lin
Dongxin Lin Chinese Academy of Sciences
Wen Tan
Wen Tan Peking Union Medical College Hospital

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