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Christopher Horst Lillig

Christopher Horst Lillig

D-Index & Metrics

Biology and Biochemistry

D-Index
44
Citations
9678
World Ranking
19231
National Ranking
1310

Overview

Christopher Horst Lillig is affiliated with the University of Greifswald in Germany. Their research primarily focuses on biochemistry, genetics, and molecular biology, with a significant emphasis on molecular biology as indicated by 47 publications in this subfield. Additional areas of study include inorganic chemistry, renewable energy, sustainability and the environment, materials chemistry, and physiology.

The scientist's work covers several main topics, among which are:

  • Redox biology and oxidative stress
  • Metal-Catalyzed Oxygenation Mechanisms
  • S100 Proteins and Annexins
  • Metalloenzymes and iron-sulfur proteins
  • Connexins and lens biology
  • Sulfur Compounds in Biology
  • Protein Structure and Dynamics

Christopher Horst Lillig has contributed to several recent scientific papers, illustrating their involvement in research exploring glutaredoxins, oxidative stress, and cellular regulation. These include:

  • "Molecular basis for the distinct functions of redox-active and FeS-transfering glutaredoxins," 2020, Nature Communications
  • "Role of GSH and Iron-Sulfur Glutaredoxins in Iron Metabolism-Review," 2020, Molecules
  • "Pentathiepins: A Novel Class of Glutathione Peroxidase 1 Inhibitors that Induce Oxidative Stress, Loss of Mitochondrial Membrane Potential and Apoptosis in Human Cancer Cells," 2020, ChemMedChem
  • "Paracrine regulation and improvement of β-cell function by thioredoxin," 2020, Redox Biology
  • "Glutaredoxin 2 Reduces Asthma-Like Acute Airway Inflammation in Mice," 2020, Frontiers in Immunology

The frequent coauthors who collaborate with Christopher Horst Lillig include:

  • Manuela Gellert
  • Yana Bodnar
  • Md Faruq Hossain
  • Eva-Maria Hanschmann
  • Carsten Berndt

The scientist regularly publishes in venues such as ChemMedChem, Redox Biology, bioRxiv (Cold Spring Harbor Laboratory), Free Radical Biology and Medicine, and The Cambridge Structural Database. These journals reflect the interdisciplinary nature of their research spanning biochemistry, molecular biology, and chemistry.

Best Publications

  • Thioredoxin and related molecules--from biology to health and disease.

    Christopher Horst Lillig;Arne Holmgren

  • Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signaling.

    Eva-Maria Hanschmann;José Rodrigo Godoy;Carsten Berndt;Christoph Hudemann

  • Thiol redox control via thioredoxin and glutaredoxin systems.

    A. Holmgren;C. Johansson;C. Berndt;M.E. Lönn

  • Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system

    Carsten Berndt;Christopher Horst Lillig;Arne Holmgren

  • Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal

    Sonia Salzano;Paola Checconi;Paola Checconi;Eva-Maria Hanschmann;Christopher Horst Lillig

  • Human Mitochondrial Glutaredoxin Reduces S-Glutathionylated Proteins with High Affinity Accepting Electrons from Either Glutathione or Thioredoxin Reductase

    Catrine Johansson;Christopher Horst Lillig;Arne Holmgren

  • Characterization of human glutaredoxin 2 as iron–sulfur protein: A possible role as redox sensor

    Christopher Horst Lillig;Carsten Berndt;Olivia Vergnolle;Maria Elisabet Lönn

  • Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster

    Ulrich Mühlenhoff;Sabine Molik;José R. Godoy;Marta A. Uzarska

  • Thioredoxins and glutaredoxins as facilitators of protein folding.

    Carsten Berndt;Christopher Horst Lillig;Christopher Horst Lillig;Arne Holmgren

  • Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release.

    Mari Enoksson;Aristi Potamitou Fernandes;Stefanie Prast;Christopher Horst Lillig

  • A novel monothiol glutaredoxin (Grx4) from Escherichia coli can serve as a substrate for thioredoxin reductase.

    Aristi Potamitou Fernandes;Malin Fladvad;Carsten Berndt;Cecilia Andrésen

  • New Thioredoxins and Glutaredoxins as Electron Donors of 3′-Phosphoadenylylsulfate Reductase

    Christopher Horst Lillig;Antje Prior;Jens Dirk Schwenn;Fredrik Åslund

  • Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide.

    Christopher Horst Lillig;Maria Elisabet Lönn;Mari Enoksson;Aristi Potamitou Fernandes

  • Glutaredoxins in thiol/disulfide exchange.

    Christopher Horst Lillig;Carsten Berndt

  • Glutathione, Glutaredoxins, and Iron.

    Carsten Berndt;Christopher Horst Lillig

  • Cold Atmospheric Plasma Treatment Induces Anti-Proliferative Effects in Prostate Cancer Cells by Redox and Apoptotic Signaling Pathways

    Martin Weiss;Denis Gümbel;Eva-Maria Hanschmann;Robert Mandelkow

  • How does iron-sulfur cluster coordination regulate the activity of human glutaredoxin 2?

    Carsten Berndt;Christoph Hudemann;Eva-Maria Hanschmann;Rebecca Axelsson

  • Redox atlas of the mouse: Immunohistochemical detection of glutaredoxin-, peroxiredoxin-, and thioredoxin-family proteins in various tissues of the laboratory mouse

    José Rodrigo Godoy;Maria Funke;Waltraud Ackermann;Petra Haunhorst

  • Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation

    Petra Haunhorst;Eva-Maria Hanschmann;Eva-Maria Hanschmann;Lars Bräutigam;Oliver Stehling

  • Thiol redox control via thioredoxin and glutaredoxin systems. Biochem Soc Trans

    A. Holmgren;C. Johansson;C. Berndt;M. E. Lönn

Frequent Co-Authors

Arne Holmgren
Arne Holmgren Karolinska Institute
Roland Lill
Roland Lill Philipp University of Marburg
Ulrich Mühlenhoff
Ulrich Mühlenhoff Philipp University of Marburg
Pietro Ghezzi
Pietro Ghezzi Brighton and Sussex Medical School
Andreas J. Meyer
Andreas J. Meyer University of Bonn
Rüdiger Hell
Rüdiger Hell Heidelberg University
Leopold Flohé
Leopold Flohé University of Padua
Markus Schwarzländer
Markus Schwarzländer University of Münster
George E. Barreto
George E. Barreto University of Limerick
Leonore A. Herzenberg
Leonore A. Herzenberg Stanford University

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