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Overview

Jane A. Mitchell is a researcher affiliated with the National Institutes of Health in the United States. Their work primarily falls within the field of Medicine, with a strong focus on Pharmacology, Pulmonary and Respiratory Medicine, Biochemistry, Cardiology and Cardiovascular Medicine, and Infectious Diseases.

The scientist's research covers several main topics, including inflammatory mediators and NSAID effects, eicosanoids and hypertension pharmacology, COVID-19 clinical research studies, antiplatelet therapy and cardiovascular diseases, nitric oxide and endothelin effects, pulmonary hypertension research and treatments, and long-term effects of COVID-19.

Jane A. Mitchell has contributed to various recent papers, among which are:

  • "A persistent neutrophil-associated immune signature characterizes post-COVID-19 pulmonary sequelae" (2022, Science Translational Medicine)
  • "Cyclooxygenases and the cardiovascular system" (2020, Pharmacology & Therapeutics)
  • "Regular Acetaminophen Use and Blood Pressure in People With Hypertension: The PATH-BP Trial" (2022, Circulation)
  • "Beyond epithelial damage: vascular and endothelial contributions to idiopathic pulmonary fibrosis" (2023, Journal of Clinical Investigation)
  • "Understanding the burden of interstitial lung disease post-COVID-19: the UK Interstitial Lung Disease-Long COVID Study (UKILD-Long COVID)" (2021, BMJ Open Respiratory Research)

The scientist frequently collaborates with several coauthors, including Nicholas S. Kirkby, Blerina Ahmetaj-Shala, Ricky Vaja, Paul C. Armstrong, and Fisnik Shala.

Publication venues where Jane A. Mitchell has appeared multiple times include Circulation, IUPHAR/BPS Guide to Pharmacology CITE, bioRxiv (Cold Spring Harbor Laboratory), Science Translational Medicine, and Scientific Reports.

Best Publications

  • Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase

    Jane A. Mitchell;Pravit Akarasereenont;Christoph Thiemermann;Roderick J. Flower

  • Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis

    Timothy D. Warner;Francesco Giuliano;Ivana Vojnovic;Antoaneta Bukasa

  • Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation

    John R. Vane;Jane A. Mitchell;Ian Appleton;Annette Tomlinson

  • The safety and side effects of monoclonal antibodies

    Trevor T. Hansel;Harald Kropshofer;Thomas Singer;Jane A. Mitchell

  • Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.

    Jennifer S. Pollock;Ulrich Forstermann;Jane A. Mitchell;Timothy D. Warner

  • Isoforms of nitric oxide synthase Characterization and purification from different cell types

    Ulrich Förstermann;Haral H.H.W. Schmidt;Jennifer S. Pollock;Hong Sheng

  • Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic

    Timothy D. Warner;Jane A. Mitchell

  • Cyclooxygenase-2: Regulation and relevance in inflammation

    Jane A. Mitchell;Simon Larkin;Timothy J. Williams

  • Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock.

    Csaba Szabó;Jane A. Mitchell;Christoph Thiemermann;John R. Vane

  • Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide

    Christoph Thiemermann;Csaba Szabo;Jane A. Mitchell;John R. Vane

  • Reactive oxygen species in acute lung injury

    F. Chabot;J. A. Mitchell;J. M. C. Gutteridge;T. W. Evans

  • Cyclo-oxygenase-2: pharmacology, physiology, biochemistry and relevance to NSAID therapy

    Jane A Mitchell;Timothy D Warner

  • Cyclooxygenase-3 (COX-3): Filling in the gaps toward a COX continuum?

    Timothy D. Warner;Jane A. Mitchell

  • Circulating MicroRNAs as Novel Biomarkers for Platelet Activation

    Peter Willeit;Anna Zampetaki;Katarzyna Dudek;Dorothee Kaudewitz

  • Co-induction of nitric oxide synthase and cyclo-oxygenase: interactions between nitric oxide and prostanoids.

    Tomasz A. Swierkosz;Jane A. Mitchell;Timothy D. Warner;Regina M. Botting

  • Induction of cyclo-oxygenase-2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone

    Jane A. Mitchell;Maria G. Belvisi;Pravit Akarasereenont;Richard A. Robbins

  • Role of nitric oxide and prostacyclin as vasoactive hormones released by the endothelium.

    Jane A. Mitchell;Ferhana Ali;Lucy Bailey;Laura Moreno

  • Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit.

    T D Warner;J A Mitchell;G de Nucci;J R Vane

  • Redox imbalance in the critically ill.

    John M C Gutteridge;Jane Mitchell

  • COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs

    Jane A. Mitchell;Timothy D. Warner

Frequent Co-Authors

Timothy D. Warner
Timothy D. Warner Queen Mary University of London
Timothy W. Evans
Timothy W. Evans Imperial College London
Maria G. Belvisi
Maria G. Belvisi Imperial College London
John R. Vane
John R. Vane St Bartholomew's Hospital
Christoph Thiemermann
Christoph Thiemermann Queen Mary University of London
Magdi H. Yacoub
Magdi H. Yacoub Imperial College London
Darryl C. Zeldin
Darryl C. Zeldin National Institutes of Health
Harvey R. Herschman
Harvey R. Herschman University of California, Los Angeles
Ulrich Förstermann
Ulrich Förstermann Johannes Gutenberg University of Mainz
Peter J. Barnes
Peter J. Barnes Imperial College London

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