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John L. Wallace

John L. Wallace

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Medicine
Canada
2023

D-Index & Metrics

Medicine

D-Index
127
Citations
55384
World Ranking
2846
National Ranking
114

Research.com Recognitions

  • 2023 - Research.com Medicine in Canada Leader Award

Overview

John L. Wallace is affiliated with the University of Calgary in Canada. Their research primarily spans the fields of medicine as well as biochemistry, genetics, and molecular biology.

The subfields of study in which they are active include biochemistry, pharmacology, physiology, surgery, and pulmonary and respiratory medicine.

Their work covers several main topics, among them:

  • Sulfur Compounds in Biology
  • Eicosanoids and Hypertension Pharmacology
  • Inflammatory mediators and NSAID effects
  • Asthma and respiratory diseases
  • Mast cells and histamine
  • Gut microbiota and health
  • Probiotics and Fermented Foods

John L. Wallace has published in multiple academic venues, frequently contributing to:

  • Antioxidants and Redox Signaling
  • Nature Reviews Gastroenterology & Hepatology
  • Journal of Crohn's and Colitis
  • International Journal for Parasitology
  • Frontiers in Pharmacology

Recent papers include:

  • Gastrointestinal biofilms in health and disease, 2021, Nature Reviews Gastroenterology & Hepatology
  • Effects of Hydrogen Sulfide on the Microbiome: From Toxicity to Therapy, 2021, Antioxidants and Redox Signaling
  • Enhanced Analgesic Effects and Gastrointestinal Safety of a Novel, Hydrogen Sulfide-Releasing Anti-Inflammatory Drug (ATB-352): A Role for Endogenous Cannabinoids, 2020, Antioxidants and Redox Signaling
  • Increased Mucosal Thrombin is Associated with Crohn's Disease and Causes Inflammatory Damage through Protease-activated Receptors Activation, 2020, Journal of Crohn's and Colitis
  • Giardia spp. promote the production of antimicrobial peptides and attenuate disease severity induced by attaching and effacing enteropathogens via the induction of the NLRP3 inflammasome, 2020, International Journal for Parasitology

Frequent collaborators in their research include:

  • Marcin Magierowski
  • André G. Buret
  • Urszula Głowacka
  • Katarzyna Magierowska
  • Dagmara Wójcik

Best Publications

  • Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon

    Gerald P. Morris;Paul L. Beck;Margaret S. Herridge;William T. Depew

  • Resolution of inflammation: state of the art, definitions and terms.

    Charles N. Serhan;Sue D. Brain;Christopher D. Buckley;Derek W. Gilroy

  • Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism.

    M Steinhoff;N Vergnolle;S H Young;M Tognetto

  • Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammation

    Renata C. O. Zanardo;Vincenzo Brancaleone;Eleonora Distrutti;Stefano Fiorucci

  • Nonsteroidal anti-inflammatory drugs and gastroenteropathy: The second hundred years

    John L. Wallace

  • Prostaglandins, NSAIDs, and Gastric Mucosal Protection: Why Doesn't the Stomach Digest Itself?

    John L. Wallace

  • NSAID-induced gastric damage in rats: Requirement for inhibition of both cyclooxygenase 1 and 2

    John L. Wallace;Webb McKnight;Brian K. Reuter;Nathalie Vergnolle

  • Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter.

    John L Wallace;Rui Wang

  • Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo

    G. Angus McQuibban;Jiang-Hong Gong;Julie P. Wong;John L. Wallace

  • Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process

    J. L. Wallace;C. M. Keenan;D. N. Granger

  • Proteinase-activated receptor-2 and hyperalgesia: A novel pain pathway.

    N. Vergnolle;N.W. Bunnett;K.A. Sharkey;V. Brussee

  • Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2.

    Brian K. Reuter;Samuel Asfaha;André Buret;Keith A. Sharkey

  • Proton Pump Inhibitors Exacerbate NSAID-Induced Small Intestinal Injury by Inducing Dysbiosis

    John L. Wallace;Stephanie Syer;Emmanuel Denou;Giada de Palma

  • Nitric oxide in mucosal defense: A little goes a long way

    John L. Wallace;Mark J.S. Miller

  • Inhibition of Hydrogen Sulfide Generation Contributes to Gastric Injury Caused by Anti-Inflammatory Nonsteroidal Drugs

    Stefano Fiorucci;Elisabetta Antonelli;Eleonora Distrutti;Giovanni Rizzo

  • The Emerging Roles of Hydrogen Sulfide in the Gastrointestinal Tract and Liver

    Stefano Fiorucci;Eleonora Distrutti;Giuseppe Cirino;John L. Wallace

  • Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease

    John L. Wallace;Wallace K. MacNaughton;Gerald P. Morris;Paul L. Beck

  • The cellular and molecular basis of gastric mucosal defense.

    J L Wallace;D N Granger

  • Human endogenous retrovirus glycoprotein-mediated induction of redox reactants causes oligodendrocyte death and demyelination.

    Joseph M Antony;Guido van Marle;Wycliffe Opii;D Allan Butterfield

  • Protease-activated receptors in inflammation, neuronal signaling and pain.

    Nathalie Vergnolle;John L Wallace;Nigel W Bunnett;Morley D Hollenberg

Frequent Co-Authors

Giuseppe Cirino
Giuseppe Cirino University of Naples Federico II
Stefano Fiorucci
Stefano Fiorucci University of Perugia
Morley D. Hollenberg
Morley D. Hollenberg University of Calgary
Andre G. Buret
Andre G. Buret University of Calgary
Paul L. Beck
Paul L. Beck University of Calgary
Brendan J.R. Whittle
Brendan J.R. Whittle Queen Mary University of London
Keith A. Sharkey
Keith A. Sharkey University of Calgary
Gilberto De Nucci
Gilberto De Nucci Universidade de São Paulo
Antonio Morelli
Antonio Morelli University of Perugia

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