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Biology and Biochemistry

D-Index
77
Citations
22687
World Ranking
4752
National Ranking
166

Overview

Paul L. Beck is affiliated with the University of Calgary in Canada. Their research primarily focuses on medicine, with significant contributions also in biochemistry, genetics, and molecular biology. Within these fields, their work addresses genetics, molecular biology, epidemiology, surgery, and immunology.

The main topics covered in their research include inflammatory bowel disease, gut microbiota and health, Helicobacter pylori-related gastroenterology studies, microscopic colitis, IL-33, ST2, and ILC pathways, colorectal cancer screening and detection, and systemic sclerosis and related diseases.

Frequent coauthors collaborating with Paul L. Beck include Kenneth Croitoru, Guy Aumais, Anne M. Griffiths, Çharles N. Bernstein, and Paul Moayyedi.

Publication venues where Paul L. Beck's work appears often include Gastroenterology, the Journal of the Canadian Association of Gastroenterology, Frontiers in Microbiology, Science Advances, and BMC Medical Genetics.

The following are some recent papers authored or coauthored by Paul L. Beck:

  • Increased Intestinal Permeability Is Associated With Later Development of Crohn's Disease, 2020, Gastroenterology
  • Novel Fecal Biomarkers That Precede Clinical Diagnosis of Ulcerative Colitis, 2020, Gastroenterology
  • Gut Microbiome Composition Is Associated With Future Onset of Crohn's Disease in Healthy First-Degree Relatives, 2023, Gastroenterology
  • Mediterranean-Like Dietary Pattern Associations With Gut Microbiome Composition and Subclinical Gastrointestinal Inflammation, 2022, Gastroenterology
  • Human interleukin-4-treated regulatory macrophages promote epithelial wound healing and reduce colitis in a mouse model, 2020, Science Advances

The research topics addressed in these papers connect with the broader areas of inflammatory bowel disease and gut microbiota studies, often exploring biomarkers, dietary influences, immune regulation, and disease progression.

Best Publications

  • Hapten-Induced Model of Chronic Inflammation and Ulceration in the Rat Colon

    Gerald P. Morris;Paul L. Beck;Margaret S. Herridge;William T. Depew

  • Intravascular danger signals guide neutrophils to sites of sterile inflammation.

    Braedon McDonald;Keir Pittman;Gustavo B. Menezes;Simon A. Hirota

  • Lipopolysaccharide Activates Distinct Signaling Pathways in Intestinal Epithelial Cell Lines Expressing Toll-Like Receptors

    Elke Cario;Ian M. Rosenberg;Steven L. Brandwein;Paul L. Beck

  • Role for protease activity in visceral pain in irritable bowel syndrome.

    Nicolas Cenac;Christopher N. Andrews;Marinella Holzhausen;Kevin Chapman

  • Effect of Oral Capsule- vs Colonoscopy-Delivered Fecal Microbiota Transplantation on Recurrent Clostridium difficile Infection: A Randomized Clinical Trial.

    Dina Kao;Brandi Roach;Marisela Silva;Paul Beck

  • Concurrent enteric helminth infection modulates inflammation and gastric immune responses and reduces helicobacter-induced gastric atrophy.

    James G. Fox;Paul Beck;Charles A. Dangler;Mark T. Whary

  • The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

    Akosua Vilaysane;Justin Chun;Mark E. Seamone;Wenjie Wang

  • Invasive potential of gut mucosa-derived Fusobacterium nucleatum positively correlates with IBD status of the host.

    Jaclyn Strauss;Gilaad G. Kaplan;Paul L. Beck;Kevin Rioux

  • Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease

    John L. Wallace;Wallace K. MacNaughton;Gerald P. Morris;Paul L. Beck

  • NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

    Simon A. Hirota;Jeffrey Ng;Alan Lueng;Maitham Khajah

  • Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis.

    Brian D Gulbransen;Mohammad Bashashati;Simon A Hirota;Xianyong Gui

  • Mice with a Selective Deletion of the CC Chemokine Receptors 5 or 2 Are Protected from Dextran Sodium Sulfate-Mediated Colitis: Lack of CC Chemokine Receptor 5 Expression Results in a NK1.1+ Lymphocyte-Associated Th2-Type Immune Response in the Intestine

    Pietro G. Andres;Paul L. Beck;Emiko Mizoguchi;Atsushi Mizoguchi

  • In Vitro-Derived Alternatively Activated Macrophages Reduce Colonic Inflammation in Mice

    Meaghan M. Hunter;Arthur Wang;Kuljit S. Parhar;Michael J.G. Johnston

  • A new look at toxic megacolon: an update and review of incidence, etiology, pathogenesis, and management.

    S Ian Gan;P L Beck

  • Gallbladder polyps: epidemiology, natural history and management.

    Robert P Myers;Eldon A Shaffer;Paul L Beck

  • Activation of natural killer T cells by α-galactosylceramide in the presence of CD1d provides protection against colitis in mice

    Lawrence J. Saubermann;Paul Beck;Ype P. De Jong;Richard S. Pitman

  • Portal hypertensive gastropathy and gastric antral vascular ectasia (GAVE) syndrome

    Burak Kw;Lee Ss;Beck Pl

  • Inflammasome-Independent NLRP3 Augments TGF-β Signaling in Kidney Epithelium

    Wenjie Wang;Xiangyu Wang;Justin Chun;Akosua Vilaysane

  • Human Placental Lactogen: Studies of Its Acute Metabolic Effects and Disposition in Normal Man

    Paul Beck;William H. Daughaday

  • Increased prevalence of circulating novel IL-17 secreting Foxp3 expressing CD4+ T cells and defective suppressive function of circulating Foxp3+ regulatory cells support plasticity between Th17 and regulatory T cells in inflammatory bowel disease patients

    Aito Ueno;Humberto Jijon;Ronald Chan;Kim Ford

Frequent Co-Authors

Gilaad G. Kaplan
Gilaad G. Kaplan University of Calgary
Remo Panaccione
Remo Panaccione University of Calgary
Subrata Ghosh
Subrata Ghosh University College Cork
Daniel A. Muruve
Daniel A. Muruve University of Calgary
Andre G. Buret
Andre G. Buret University of Calgary
John L. Wallace
John L. Wallace University of Calgary
Herman W. Barkema
Herman W. Barkema University of Calgary
Morley D. Hollenberg
Morley D. Hollenberg University of Calgary
Daniel K. Podolsky
Daniel K. Podolsky The University of Texas at Dallas
Ramnik J. Xavier
Ramnik J. Xavier Broad Institute

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