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Daniel A. Muruve

Daniel A. Muruve

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
18158
World Ranking
12308
National Ranking
424

Overview

Daniel A. Muruve is affiliated with the University of Calgary in Canada and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research spans multiple interconnected subfields including molecular biology, immunology, infectious diseases, nephrology, and neurology.

The scientist's main research topics cover inflammasome and immune disorders, renal diseases and glomerulopathies, COVID-19 clinical research studies, SARS-CoV-2 and COVID-19 research, neuroinflammation and neurodegeneration mechanisms, heme oxygenase-1 and carbon monoxide, and acute kidney injury research.

Recent notable publications include:

  • "Gasdermins and pyroptosis in the kidney" (2023) published in Nature Reviews Nephrology
  • "Dexamethasone sensitizes to ferroptosis by glucocorticoid receptor-induced dipeptidase-1 expression and glutathione depletion" (2022) published in Science Advances
  • "Dipeptidase-1 governs renal inflammation during ischemia reperfusion injury" (2022) published in Science Advances
  • "Hyperactivity of Innate Immunity Triggers Pain via TLR2-IL-33-Mediated Neuroimmune Crosstalk" (2020) published in Cell Reports
  • "A B1a-natural IgG-neutrophil axis is impaired in viral- and steroid-associated aspergillosis" (2022) published in Science Translational Medicine

Frequent publication venues for this researcher include:

  • Kidney International Reports
  • Journal of the American Society of Nephrology
  • Science Advances
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Reviews Nephrology

Key frequent co-authors collaborating with Daniel A. Muruve are:

  • Justin Chun
  • Hyunjae Chung
  • Graciela Andonegui
  • Arthur Lau
  • Esteban Elias

The scientist's work integrates clinical and molecular approaches, particularly focusing on immune and inflammatory mechanisms related to kidney injury and systemic infections, with implications for COVID-19 and neuroimmune interactions.

Best Publications

  • Intravascular danger signals guide neutrophils to sites of sterile inflammation.

    Braedon McDonald;Keir Pittman;Gustavo B. Menezes;Simon A. Hirota

  • The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response

    Daniel A. Muruve;Virginie Pétrilli;Anne K. Zaiss;Lindsay R. White

  • The inflammasome: a danger sensing complex triggering innate immunity.

    Virginie Pétrilli;Catherine Dostert;Daniel A Muruve;Jürg Tschopp

  • Inflammasomes in the CNS

    John G. Walsh;Daniel A. Muruve;Christopher Power

  • The NLRP3 Inflammasome Promotes Renal Inflammation and Contributes to CKD

    Akosua Vilaysane;Justin Chun;Mark E. Seamone;Wenjie Wang

  • The Innate Immune Response to Adenovirus Vectors

    Daniel A Muruve

  • Adenoviral gene therapy leads to rapid induction of multiple chemokines and acute neutrophil-dependent hepatic injury in vivo.

    Daniel A. Muruve;Melissa J. Barnes;Isaac E. Stillman;Towia A. Libermann

  • Molecular basis of the inflammatory response to adenovirus vectors.

    Q Liu;D A Muruve

  • Calcium oxalate crystals induce renal inflammation by NLRP3-mediated IL-1β secretion

    Shrikant R. Mulay;Onkar P. Kulkarni;Khader V. Rupanagudi;Adriana Migliorini

  • Differential Activation of Innate Immune Responses by Adenovirus and Adeno-Associated Virus Vectors

    Anne-Kathrin Zaiss;Qiang Liu;Gloria P. Bowen;Norman C. W. Wong

  • NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis

    Simon A. Hirota;Jeffrey Ng;Alan Lueng;Maitham Khajah

  • Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis.

    Brian D Gulbransen;Mohammad Bashashati;Simon A Hirota;Xianyong Gui

  • Alum interaction with dendritic cell membrane lipids is essential for its adjuvanticity

    Tracy L Flach;Gilbert Ng;Aswin Hari;Melanie D Desrosiers

  • The Inflammasomes in Kidney Disease

    Hans-Joachim Anders;Daniel A. Muruve

  • NOD-like receptors and inflammasomes: A review of their canonical and non-canonical signaling pathways.

    Jaye M. Platnich;Daniel A. Muruve

  • Immune responses to adeno-associated virus vectors.

    Anne K Zaiss;Daniel A Muruve

  • The role of inflammasomes in kidney disease.

    Takanori Komada;Daniel A. Muruve

  • Clostridium difficile Toxin–Induced Inflammation and Intestinal Injury Are Mediated by the Inflammasome

    Jeffrey Ng;Simon A. Hirota;Olaf Gross;Yan Li

  • Immunity to adeno-associated virus vectors in animals and humans: a continued challenge.

    A K Zaiss;D A Muruve

  • Inflammasome-Independent NLRP3 Augments TGF-β Signaling in Kidney Epithelium

    Wenjie Wang;Xiangyu Wang;Justin Chun;Akosua Vilaysane

Frequent Co-Authors

Paul L. Beck
Paul L. Beck University of Calgary
Jürg Tschopp
Jürg Tschopp University of Lausanne
Brenda R. Hemmelgarn
Brenda R. Hemmelgarn University of Calgary
Paul Kubes
Paul Kubes University of Calgary
Towia A. Libermann
Towia A. Libermann Beth Israel Deaconess Medical Center
Daniel J. Hassett
Daniel J. Hassett University of Cincinnati Medical Center
Robin J. Parks
Robin J. Parks Ottawa Hospital
Subrata Ghosh
Subrata Ghosh University College Cork
Sean P. Colgan
Sean P. Colgan University of Colorado Anschutz Medical Campus
Dongyang Li
Dongyang Li University of Alberta

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