World's Best Scientists 2026 revealed!
James G. Fox

James G. Fox

Award Badge
Microbiology
USA
2026

D-Index & Metrics

Microbiology

D-Index
132
Citations
61177
World Ranking
74
National Ranking
36

Medicine

D-Index
133
Citations
63989
World Ranking
2235
National Ranking
1261

Research.com Recognitions

  • 2026 - Research.com Microbiology in United States Leader Award
  • 2025 - Research.com Microbiology in United States Leader Award

Overview

James G. Fox is affiliated with MIT in the United States and has contributed extensively to research primarily in Medicine and Biochemistry, Genetics, and Molecular Biology. Their work spans several key subfields including Immunology, Surgery, Molecular Biology, Oncology, and Genetics.

The scientist's research topics cover a variety of areas with a significant focus on infectious diseases and immune response mechanisms. These include:

  • Helicobacter pylori-related gastroenterology studies
  • Gut microbiota and health
  • IL-33, ST2, and ILC Pathways
  • Immune Cell Function and Interaction
  • Escherichia coli research studies
  • Antibiotic Resistance in Bacteria
  • Cancer Immunotherapy and Biomarkers

Recent notable publications demonstrate the range and impact of their research:

  • "ILC3s select microbiota-specific regulatory T cells to establish tolerance in the gut" (2022, Nature)
  • "PD-1 Signaling Promotes Tumor-Infiltrating Myeloid-Derived Suppressor Cells and Gastric Tumorigenesis in Mice" (2020, Gastroenterology)
  • "Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis" (2021, Cell Stem Cell)
  • "Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer" (2023, Immunity)
  • "Opportunities and limitations of genetically modified nonhuman primate models for neuroscience research" (2020, Proceedings of the National Academy of Sciences)

Throughout their career, Fox has collaborated frequently with several other researchers, including:

  • Zeli Shen
  • Sureshkumar Muthupalani
  • Anthony Mannion
  • Alexander Sheh
  • JoAnn Dzink-Fox

James G. Fox has published multiple articles in prominent scientific venues, often contributing to journals that focus on dermatology, general biomedical research, and comparative medicine. Frequent publication venues include:

  • Scientific Reports
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Investigative Dermatology
  • UNC Libraries
  • Comparative Medicine

Best Publications

  • CX3CR1-Mediated Dendritic Cell Access to the Intestinal Lumen and Bacterial Clearance

    Jan Hendrik Niess;Stephan Brand;Xiubin Gu;Limor Landsman

  • Gastric cancer originating from bone marrow-derived cells.

    JeanMarie Houghton;Calin Stoicov;Sachiyo Nomura;Sachiyo Nomura;Arlin B. Rogers

  • Inflammation, atrophy, and gastric cancer

    James G. Fox;Timothy C. Wang

  • Overexpression of Interleukin-1β Induces Gastric Inflammation and Cancer and Mobilizes Myeloid-Derived Suppressor Cells in Mice

    Shuiping Tu;Govind Bhagat;Guanglin Cui;Shigeo Takaishi

  • Commensal Microbiota Promote Lung Cancer Development via γδ T Cells.

    Chengcheng Jin;Georgia K. Lagoudas;Chen Zhao;Susan Bullman;Susan Bullman

  • Laboratory animal medicine

    James G. Fox;Bennett J. Cohen;Franklin M. Loew

  • Contaminated heparin associated with adverse clinical events and activation of the contact system.

    Takashi Kei Kishimoto;Karthik Viswanathan;Tanmoy Ganguly;Subbiah Elankumaran

  • Hepatic Helicobacter species identified in bile and gallbladder tissue from chileans with chronic cholecystitis

    James G. Fox;Floyd E. Dewhirst;Zeli Shen;Yan Feng

  • Synergistic interaction between hypergastrinemia and Helicobacter infection in a mouse model of gastric cancer.

    Timothy C. Wang;Charles A. Dangler;Duan Chen;James R. Goldenring

  • Gremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.

    Daniel L. Worthley;Michael Churchill;Jocelyn T. Compton;Yagnesh Tailor

  • DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice

    Lisiane B. Meira;James M. Bugni;Stephanie L. Green;Chung-Wei Lee

  • Denervation suppresses gastric tumorigenesis

    Chun-Mei Zhao;Yoku Hayakawa;Yosuke Kodama;Sureshkumar Muthupalani

  • Helicobacter hepaticus sp. nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice.

    J G Fox;F E Dewhirst;J G Tully;B J Paster

  • Concurrent enteric helminth infection modulates inflammation and gastric immune responses and reduces helicobacter-induced gastric atrophy.

    James G. Fox;Paul Beck;Charles A. Dangler;Mark T. Whary

  • Activation of β-catenin by carcinogenic Helicobacter pylori

    Aime T. Franco;Dawn A. Israel;Mary K. Washington;Uma Krishna

  • Helicobacter pylori and gastric carcinoma. Serum antibody prevalence in populations with contrasting cancer risks.

    Pelayo Correa;Pelayo Correa;James Fox;Elizabeth Fontham;Bernardo Ruiz

  • Arsenic Exposure Perturbs the Gut Microbiome and Its Metabolic Profile in Mice: An Integrated Metagenomics and Metabolomics Analysis

    Kun Lu;Ryan Phillip Abo;Katherine Ann Schlieper;Michelle E. Graffam

  • The Mouse in biomedical research

    James G. Fox;Stephen W Barthold;Muriel T. Davisson;Christian E. Newcomer

  • Chronic active hepatitis and associated liver tumors in mice caused by a persistent bacterial infection with a novel Helicobacter species.

    Jerrold M. Ward;James G. Fox;Miriam R. Anver;Diana C. Haines

  • A small animal model of human Helicobacter pylori active chronic gastritis.

    Adrian Lee;James G. Fox;Glen Otto;James Murphy

  • Biology and diseases of the ferret.

    James G. Fox;Robert P. Marini

  • Commensal Microbiota Promote Lung Cancer Development via γδ T Cells

    Chengcheng Jin;Georgia K Lagoudas;Arjun Bhutkar;Samuel Ameh

Frequent Co-Authors

Timothy C. Wang
Timothy C. Wang Columbia University
Floyd E. Dewhirst
Floyd E. Dewhirst Harvard University
Bruce J. Paster
Bruce J. Paster Harvard University
Bruce H. Horwitz
Bruce H. Horwitz Harvard Medical School
Pelayo Correa
Pelayo Correa Vanderbilt University
Scott B. Snapper
Scott B. Snapper Boston Children's Hospital
Ronald G. Tompkins
Ronald G. Tompkins Harvard University

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