Bruce H. Horwitz

Overview

Best Publications

• Regulation of PD-1, PD-L1, and PD-L2 expression during normal and autoimmune responses.

  Spencer C Liang;Yvette E Latchman;Janet E Buhlmann;Michal F Tomczak

  858
  Citations

• Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

  Dror S. Shouval;Dror S. Shouval;Amlan Biswas;Amlan Biswas;Jeremy A. Goettel;Jeremy A. Goettel;Katelyn McCann

  642
  Citations

• CD4+ CD25+ Regulatory T Lymphocytes Inhibit Microbially Induced Colon Cancer in Rag2-Deficient Mice

  Susan E. Erdman;Theofilos Poutahidis;Michal Tomczak;Arlin B. Rogers

  423
  Citations

• Targeted Mutation of TNF Receptor I Rescues the RelA-Deficient Mouse and Reveals a Critical Role for NF-κB in Leukocyte Recruitment

  Elizabeth Alcamo;Joseph P. Mizgerd;Bruce H. Horwitz;Rod Bronson

  377
  Citations

• Impaired local intrinsic immunity to SARS-CoV-2 infection in severe COVID-19.

  Carly G K Ziegler;Vincent N Miao;Anna H Owings;Andrew W Navia

  366
  Citations

• Interleukin 10 receptor signaling: master regulator of intestinal mucosal homeostasis in mice and humans.

  Dror S. Shouval;Jodie Ouahed;Amlan Biswas;Jeremy A. Goettel

  350
  Citations

• Single-Cell Analyses of Colon and Blood Reveal Distinct Immune Cell Signatures of Ulcerative Colitis and Crohn's Disease.

  Vanessa Mitsialis;Vanessa Mitsialis;Sarah Wall;Peng Liu;Jose Ordovas-Montanes;Jose Ordovas-Montanes;Jose Ordovas-Montanes

  322
  Citations

• Induction of activation‐induced cytidine deaminase gene expression by IL‐4 and CD40 ligation is dependent on STAT6 and NFκB

  Fatma Dedeoglu;Bruce Horwitz;Jayanta Chaudhuri;Frederick W. Alt

  292
  Citations

• Failure of Lymphopoiesis after Adoptive Transfer of NF-κB–Deficient Fetal Liver Cells

  Bruce H Horwitz;Bruce H Horwitz;Martin L Scott;Sara R Cherry;Roderick T Bronson

  277
  Citations

• Gastroenteritis in NF-κB-Deficient Mice Is Produced with Wild-Type Camplyobacter jejuni but Not with C. jejuni Lacking Cytolethal Distending Toxin despite Persistent Colonization with Both Strains

  James G. Fox;Arlin B. Rogers;Mark T. Whary;Zhongming Ge

  267
  Citations

• CD4(+)CD25(+) Regulatory Lymphocytes Require Interleukin 10 to Interrupt Colon Carcinogenesis in Mice

  Susan E. Erdman;Varada P. Rao;Theofilos Poutahidis;Melanie M. Ihrig

  250
  Citations

• Innate Immune Inflammatory Response against Enteric Bacteria Helicobacter hepaticus Induces Mammary Adenocarcinoma in Mice

  Varada P. Rao;Theofilos Poutahidis;Zhongming Ge;Prashant R. Nambiar

  227
  Citations

• Nuclear factor kappa B is required for the development of marginal zone B lymphocytes.

  Annaiah Cariappa;Hsiou-Chi Liou;Bruce H. Horwitz;Shiv Pillai

  227
  Citations

• Helicobacter hepaticus infection in mice: models for understanding lower bowel inflammation and cancer

  J G Fox;Z Ge;M T Whary;S E Erdman

  209
  Citations

• Cutting Edge: Typhlocolitis in NF-κB-Deficient Mice

  Susan E. Erdman;James G. Fox;Charles A. Dangler;Danielle Feldman

  198
  Citations

• Interleukin 1β Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency

  Dror S. Shouval;Amlan Biswas;Amlan Biswas;Yu Hui Kang;Yu Hui Kang;Alexandra E. Griffith

  192
  Citations

• Endothelial TNF Receptor 2 Induces IRF1 Transcription Factor-Dependent Interferon-β Autocrine Signaling to Promote Monocyte Recruitment

  Deepak Venkatesh;Thomas Ernandez;Florencia Rosetti;Florencia Rosetti;Ibrahim Batal

  148
  Citations

• A Role for NF-κB Subunits p50 and p65 in the Inhibition of Lipopolysaccharide-Induced Shock

  Mihaela Gadjeva;Michal F. Tomczak;Ming Zhang;Yan Yan Wang

  134
  Citations

• Effects of CD18 deficiency on the emigration of murine neutrophils during pneumonia.

  Joseph P. Mizgerd;Bruce H. Horwitz;Bruce H. Horwitz;Henry C. Quillen;Martin L. Scott;Martin L. Scott

  129
  Citations

• Proinflammatory CD4+CD45RBhi Lymphocytes Promote Mammary and Intestinal Carcinogenesis in ApcMin/+ Mice

  Varada P. Rao;Theofilos Poutahidis;Zhongming Ge;Prashant R. Nambiar

  118
  Citations