World's Best Scientists 2026 revealed!
Zhongming Ge

Zhongming Ge

D-Index & Metrics

Microbiology

D-Index
53
Citations
9420
World Ranking
4109
National Ranking
1593

Overview

Zhongming Ge is affiliated with the Massachusetts Institute of Technology (MIT) in the United States and has contributed extensively to research in medicine, biochemistry, genetics, and molecular biology. Their research spans multiple subfields, including surgery, molecular biology, pulmonary and respiratory medicine, immunology, and infectious diseases.

The scientist's work covers several key topics:

  • Helicobacter pylori-related gastroenterology studies
  • Gastric cancer management and outcomes
  • Hippo pathway signaling and YAP/TAZ
  • Cancer-related gene regulation
  • Veterinary medicine and infectious diseases
  • Ferroptosis and cancer prognosis
  • RNA modifications and cancer

Zhongming Ge has published research articles in several journals with repeated contributions to venues such as Comparative Medicine, Gastric Cancer, Gut Microbes, International Journal of Molecular Sciences, and the Journal of Advanced Research.

Notable recent papers authored or co-authored by Zhongming Ge include:

  • "Convergent dysbiosis of gastric mucosa and fluid microbiome during stomach carcinogenesis," 2022, Gastric Cancer
  • "YAP and β-catenin cooperate to drive H. pylori-induced gastric tumorigenesis," 2023, Gut Microbes
  • "Single-cell transcriptomic profiling uncovers cellular complexity and microenvironment in gastric tumorigenesis associated with Helicobacter pylori," 2024, Journal of Advanced Research
  • "Helicobacter pylori antibiotic eradication coupled with a chemically defined diet in INS-GAS mice triggers dysbiosis and vitamin K deficiency resulting in gastric hemorrhage," 2020, Gut Microbes
  • "Identification of a new strain of mouse kidney parvovirus associated with inclusion body nephropathy in immunocompromised laboratory mice," 2020, Emerging Microbes & Infections

The scientist has also contributed to book publications, including a title published by Frontiers Media: Helicobacter pylori-Transmission, Pathogenesis, Host-pathogen interaction, Prevention and Treatment (2023).

Frequent co-authors collaborating with Zhongming Ge include:

  • Cong He
  • James G. Fox
  • Yaobin Ouyang
  • Yi Hu
  • Nianshuang Li

Best Publications

  • Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia.

    Jennifer L. Lofgren;Mark T. Whary;Zhongming Ge;Sureshkumar Muthupalani

  • Gastric colonisation with a restricted commensal microbiota replicates the promotion of neoplastic lesions by diverse intestinal microbiota in the Helicobacter pylori INS-GAS mouse model of gastric carcinogenesis

    Kvin Lertpiriyapong;Mark T Whary;Sureshkumar Muthupalani;Jennifer L Lofgren

  • Cloning and sequence analysis of two copies of a 23S rRNA gene from Helicobacter pylori and association of clarithromycin resistance with 23S rRNA mutations.

    D E Taylor;Z Ge;D Purych;T Lo

  • The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus

    Sebastian Suerbaum;Christine Josenhans;Torsten Sterzenbach;Bernd Drescher

  • Infection-induced colitis in mice causes dynamic and tissue-specific changes in stress response and DNA damage leading to colon cancer

    Aswin Mangerich;Charles G. F. Knutson;Nicola Maria Anne Parry;Sureshkumar Muthupalani

  • Gastroenteritis in NF-κB-Deficient Mice Is Produced with Wild-Type Camplyobacter jejuni but Not with C. jejuni Lacking Cytolethal Distending Toxin despite Persistent Colonization with Both Strains

    James G. Fox;Arlin B. Rogers;Mark T. Whary;Zhongming Ge

  • CD4+CD25+ Regulatory Lymphocytes Induce Regression of Intestinal Tumors in ApcMin/+ Mice

    Susan E. Erdman;Jane J. Sohn;Varada P. Rao;Prashant R. Nambiar

  • CD4(+)CD25(+) Regulatory Lymphocytes Require Interleukin 10 to Interrupt Colon Carcinogenesis in Mice

    Susan E. Erdman;Varada P. Rao;Theofilos Poutahidis;Melanie M. Ihrig

  • Disruption of Tight Junctions and Induction of Proinflammatory Cytokine Responses in Colonic Epithelial Cells by Campylobacter jejuni

    Ming L. Chen;Zhongming Ge;James G. Fox;David B. Schauer

  • Host and microbial constituents influence helicobacter pylori-induced cancer in a murine model of hypergastrinemia

    James G Fox;Timothy C Wang;Arlin B Rogers;Theofilos Poutahidis

  • Probiotic Lactobacillus spp. diminish Helicobacter hepaticus-induced inflammatory bowel disease in interleukin-10-deficient mice.

    Jeremy A. Peña;Jeremy A. Peña;Arlin B. Rogers;Zhongming Ge;Vivian Ng

  • Innate Immune Inflammatory Response against Enteric Bacteria Helicobacter hepaticus Induces Mammary Adenocarcinoma in Mice

    Varada P. Rao;Theofilos Poutahidis;Zhongming Ge;Prashant R. Nambiar

  • Nitric oxide and TNF-α trigger colonic inflammation and carcinogenesis in Helicobacter hepaticus-infected, Rag2-deficient mice

    S. E. Erdman;V. P. Rao;T. Poutahidis;A. B. Rogers

  • Helicobacter hepaticus infection in mice: models for understanding lower bowel inflammation and cancer

    J G Fox;Z Ge;M T Whary;S E Erdman

  • Lewis antigens in Helicobacter pylori: biosynthesis and phase variation.

    Ge Wang;Zhongming Ge;David A. Rasko;Diane E. Taylor

  • Campylobacter jejuni Type VI Secretion System: Roles in Adaptation to Deoxycholic Acid, Host Cell Adherence, Invasion, and In Vivo Colonization

    Kvin Lertpiriyapong;Eric R. Gamazon;Yan Feng;Danny S. Park

  • Spatial Distribution and Stability of the Eight Microbial Species of the Altered Schaedler Flora in the Mouse Gastrointestinal Tract

    Ramahi B. Sarma-Rupavtarm;Zhongming Ge;David B. Schauer;James G. Fox

  • Identification of cdtB homologues and cytolethal distending toxin activity in enterohepatic Helicobacter spp.

    Chih Ching Chien;Nancy S. Taylor;Zhongming Ge;David B. Schauer

  • In vivo virulence properties of bacterial cytolethal-distending toxin.

    Zhongming Ge;David B. Schauer;James G. Fox

  • Cloning and Heterologous Expression of an α1,3-Fucosyltransferase Gene from the Gastric PathogenHelicobacter pylori

    Zhongming Ge;Nora W.C. Chan;Monica M. Palcic;Diane E. Taylor

  • Bacterial cytolethal distending toxin promotes the development of dysplasia in a model of microbially induced hepatocarcinogenesis.

    Zhongming Ge;Arlin B. Rogers;Yan Feng;Amy Lee

Frequent Co-Authors

Timothy C. Wang
Timothy C. Wang Columbia University
Diane E. Taylor
Diane E. Taylor University of Alberta
Bruce H. Horwitz
Bruce H. Horwitz Harvard Medical School
Sebastian Suerbaum
Sebastian Suerbaum Ludwig-Maximilians-Universität München
Amy S. Lee
Amy S. Lee University of Southern California
Eric R. Gamazon
Eric R. Gamazon Vanderbilt University Medical Center

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