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John S. Wishnok

John S. Wishnok

D-Index & Metrics

Chemistry

D-Index
63
Citations
35467
World Ranking
8257
National Ranking
2385

Overview

John S. Wishnok is a researcher affiliated with MIT in the United States. Their work spans key areas within environmental science and biochemistry, genetics, and molecular biology, focusing on interactions between environmental toxins and biological systems.

The scientist's research covers core themes including arsenic contamination and mitigation, gut microbiota and health, fluoride effects and removal, as well as Alzheimer's disease research and treatments. Additional topics include S100 proteins and annexins, receptor mechanisms and signaling, and heavy metal exposure and toxicity.

Frequently published in several notable venues, Wishnok's work has appeared in:

  • UNC Libraries
  • OPAL (Open@LaTrobe) (La Trobe University)
  • Science Advances
  • International Journal of Molecular Sciences

Among the recent papers authored by Wishnok are:

  • Mechanistic insight into female predominance in Alzheimer's disease based on aberrant protein S-nitrosylation of C3, 2022, Science Advances
  • Low Doses of Arsenic in a Mouse Model of Human Exposure and in Neuronal Culture Lead to S-Nitrosylation of Synaptic Proteins and Apoptosis via Nitric Oxide, 2020, International Journal of Molecular Sciences
  • Arsenic Exposure Perturbs the Gut Microbiome and Its Metabolic Profile in Mice: An Integrated Metagenomics and Metabolomics Analysis, 2020, UNC Libraries
  • Gut Microbiome Perturbations Induced by Bacterial Infection Affect Arsenic Biotransformation, 2020, OPAL (Open@LaTrobe) (La Trobe University)
  • Gut Microbiome Phenotypes Driven by Host Genetics Affect Arsenic Metabolism, 2020, OPAL (Open@LaTrobe) (La Trobe University)

Wishnok frequently collaborates with other researchers, including:

  • Steven R. Tannenbaum
  • James A. Swenberg
  • James G. Fox
  • Hongmei Yang
  • Haitham Amal

In terms of fields of study, Wishnok's work is categorized mainly under Environmental Science with six publications, and Biochemistry, Genetics, and Molecular Biology with four publications. The subfields include:

  • Molecular Biology
  • Environmental Chemistry
  • Water Science and Technology
  • Physiology
  • Health, Toxicology and Mutagenesis

Best Publications

  • Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids

    Laura C. Green;David A. Wagner;Joseph Glogowski;Paul L. Skipper

  • Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate.

    Michael A. Marletta;Poksyn S. Yoon;Radha Iyengar;Cynthia D. Leaf

  • DNA damage and mutation in human cells exposed to nitric oxide in vitro.

    T Nguyen;D Brunson;C L Crespi;B W Penman

  • The chemistry of DNA damage from nitric oxide and peroxynitrite

    Samar Burney;Jennifer L. Caulfield;Jacquin C. Niles;John S. Wishnok

  • Arsenic Exposure Perturbs the Gut Microbiome and Its Metabolic Profile in Mice: An Integrated Metagenomics and Metabolomics Analysis

    Kun Lu;Ryan Phillip Abo;Katherine Ann Schlieper;Michelle E. Graffam

  • The chemistry of the S-nitrosoglutathione/glutathione system

    S. P. Singh;J. S. Wishnok;M. Keshive;W. M. Deen

  • Activation by nitric oxide of an oxidative-stress response that defends Escherichia coli against activated macrophages

    Tatsuo Nunoshiba;Teresa Derojas-Walker;John S. Wishnok;Steven R. Tannenbaum

  • Nitric oxide induces oxidative damage in addition to deamination in macrophage DNA.

    Teresa deRojas-Walker;Snait Tamir;Hong Ji;John S. Wishnok

  • Phosphorothioation of DNA in bacteria by dnd genes

    Lianrong Wang;Shi Chen;Shi Chen;Tiegang Xu;Koli Taghizadeh

  • Nitromation of amines by stimulated macrophages

    Misao Miwa;Dennis J. Stuehr;Michael A. Marletta;John S. Wishnok

  • Nitric Oxide-induced Deamination of Cytosine and Guanine in Deoxynucleosides and Oligonucleotides

    Jennifer L. Caulfield;John S. Wishnok;Steven R. Tannenbaum

  • Inhibition of nitrosamine formation by ascorbic acid.

    S R Tannenbaum;J S Wishnok;C D Leaf

  • Peroxynitrite-induced oxidation and nitration products of guanine and 8-oxoguanine: structures and mechanisms of product formation.

    Jacquin C. Niles;John S. Wishnok;Steven R. Tannenbaum

  • Hydrogen Peroxide-Supported Oxidation of NG-Hydroxy-L-Arginine by Nitric Oxide Synthase

    Robert A. Pufahl;John S. Wishnok;Michael A. Marletta

  • AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo

    James C Delaney;Lisa Smeester;Cintyu Wong;Lauren E Frick

  • PGE2-regulated wnt signaling and N-acetylcysteine are synergistically hepatoprotective in zebrafish acetaminophen injury

    Trista E. North;I. Ramesh Babu;Lea M. Vedder;Allegra M. Lord

  • Lipid peroxidation dominates the chemistry of DNA adduct formation in a mouse model of inflammation

    Bo Pang;Xinfeng Zhou;Hongbin Yu;Min Dong

  • Spiroiminodihydantoin is the major product of the 8-oxo-7,8-dihydroguanosine reaction with peroxynitrite in the presence of thiols and guanosine photooxidation by methylene blue.

    Jacquin C. Niles;John S. Wishnok;Steven R. Tannenbaum

  • Kinetics of S-nitrosation of thiols in nitric oxide solutions.

    Manish Keshive;Sukhjeet Singh;John S. Wishnok;Steven R. Tannenbaum

  • L-Arginine is a precursor for nitrate biosynthesis in humans

    Cynthia D. Leaf;John S. Wishnok;Steven R. Tannenbaum

  • Bicarbonate Inhibits N-Nitrosation in Oxygenated Nitric Oxide Solutions *

    Jennifer L. Caulfield;Sukhjeet P. Singh;John S. Wishnok;William M. Deen

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