World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
22543
World Ranking
3195
National Ranking
1615

Overview

David J. Ecker is affiliated with Ionis Pharmaceuticals in the United States. Their research work spans multiple fields of study, primarily focusing on medicine and biochemistry, genetics, and molecular biology. Within these broad areas, their work includes subfields such as molecular biology, public health, environmental and occupational health, genetics, parasitology, and epidemiology.

Their research topics cover several key areas, including telemedicine and telehealth implementation, the impacts of COVID-19 on healthcare, healthcare systems and technology, histone deacetylase inhibitors, epigenetics and DNA methylation, genetics and neurodevelopmental disorders, and vector-borne infectious diseases.

David J. Ecker has contributed to various scientific publications, with recent papers including:

  • "Opportunities and challenges for innovative and equitable healthcare," 2024, Nature Reviews Drug Discovery
  • "Telehealth: from the abstract to necessity to competency," 2021, FASEB BioAdvances
  • "An Antisense Oligonucleotide Leads to Suppressed Transcription of Hdac2 and Long-Term Memory Enhancement," 2020, Molecular Therapy - Nucleic Acids
  • "Molecular Microbiological and Immune Characterization of a Cohort of Patients Diagnosed with Early Lyme Disease," 2020, Journal of Clinical Microbiology
  • "Threat Net: A Metagenomic Surveillance Network for Biothreat Detection and Early Warning," 2023, Health Security

The list of frequent co-authors collaborating with David J. Ecker includes Jennifer E. Adams, Shane G. Poplawski, Krassimira Garbett, Rebekah L. McMahan, and Holly Kordasiewicz.

Scientific findings by David J. Ecker have been published across several journals such as FASEB BioAdvances, Molecular Therapy - Nucleic Acids, Journal of Clinical Microbiology, Nature Reviews Drug Discovery, and Health Security, reflecting a diverse engagement with both clinical and molecular aspects of biomedical research.

Best Publications

  • A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein.

    Vincent Chau;John W. Tobias;Andreas Bachmair;Andreas Bachmair;David Marriott

  • Analysis of Antibiotic Resistance Genes in Multidrug-Resistant Acinetobacter sp. Isolates from Military and Civilian Patients Treated at the Walter Reed Army Medical Center

    Kristine M. Hujer;Andrea M. Hujer;Edward A. Hulten;Saralee Bajaksouzian

  • RNAMotif, an RNA secondary structure definition and search algorithm

    Thomas J. Macke;David J. Ecker;Robin R. Gutell;Daniel Gautheret

  • Inhibition of proteolysis and cell cycle progression in a multiubiquitination-deficient yeast mutant.

    Daniel Finley;Seth Sadis;Brett P. Monia;Paul Boucher

  • Ibis T5000: a universal biosensor approach for microbiology.

    David J. Ecker;Rangarajan Sampath;Christian Massire;Lawrence B. Blyn

  • Combinatorially selected guanosine-quartet structure is a potent inhibitor of human immunodeficiency virus envelope-mediated cell fusion.

    Jacqueline R. Wyatt;Timothy A. Vickers;Joseph L. Roberson;Robert W. Buckheit

  • Effects of phosphorothioate capping on antivense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection

    Glenn D. Hoke;Kenneth Draper;Susan M. Freier;Carolyn Gonzalez

  • Selective inhibition of mutant Ha-ras mRNA expression by antisense oligonucleotides.

    B P Monia;J F Johnston;D J Ecker;M A Zounes

  • Long-term effects of culture of preimplantation mouse embryos on behavior

    David J. Ecker;Paula Stein;Zhe Xu;Carmen J. Williams

  • Prediction of rho-independent transcriptional terminators in Escherichia coli

    Elena A. Lesnik;Rangarajan Sampath;Harold B. Levene;Timothy J. Henderson

  • Implication of RNA structure on antisense oligonucleotide hybridization kinetics.

    Walt F. Lima;Brett P. Monia;David J. Ecker;Susan M. Freier

  • A bioinformatics based approach to discover small RNA genes in the Escherichia coli genome.

    Shuo Chen;Elena A. Lesnik;Thomas A. Hall;Rangarajan Sampath

  • Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

    E A Lesnik;C J Guinosso;A M Kawasaki;H Sasmor

  • Rapid identification and strain-typing of respiratory pathogens for epidemic surveillance

    David J. Ecker;Rangarajan Sampath;Lawrence B. Blyn;Mark W. Eshoo

  • Structure−Activity Relationships of Novel 2-Substituted Quinazoline Antibacterial Agents

    P P Kung;M D Casper;K L Cook;L Wilson-Lingardo

  • TIGER: the universal biosensor

    Steven A. Hofstadler;Rangarajan Sampath;Lawrence B. Blyn;Mark W. Eshoo

  • Carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae across a hospital system: impact of post-acute care facilities on dissemination

    Federico Perez;Andrea Endimiani;Andrea Endimiani;Amy J. Ray;Brooke K. Decker

  • De novo initiation of viral RNA-dependent RNA synthesis.

    C.Cheng Kao;Paul Singh;David J. Ecker

  • Chemical Modifications to Improve Uptake and Bioavailability of Antisense Oligonucleotides

    M. Manoharan;L. K. Johnson;D. P. C. McGEE;C. J. Guinosso

  • Identification of Acinetobacter Species and Genotyping of Acinetobacter baumannii by Multilocus PCR and Mass Spectrometry

    Joseph A. Ecker;Christian Massire;Thomas A. Hall;Raymond Ranken

Frequent Co-Authors

Rangarajan Sampath
Rangarajan Sampath University of California San Diego
Lawrence B. Blyn
Lawrence B. Blyn Ionis Pharmaceuticals (United States)
Stanley T. Crooke
Stanley T. Crooke Ionis Pharmaceuticals (United States)
Phillip Dan Cook
Phillip Dan Cook Ionis Pharmaceuticals (United States)
Robert A. Bonomo
Robert A. Bonomo Case Western Reserve University
C. Frank Bennett
C. Frank Bennett Ionis Pharmaceuticals (United States)
Brett P. Monia
Brett P. Monia Ionis Pharmaceuticals (United States)
Kristine M. Hujer
Kristine M. Hujer Case Western Reserve University
Ole Buchardt
Ole Buchardt University of Copenhagen
Andrea M. Hujer
Andrea M. Hujer United States Department of Veterans Affairs

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