Alexander Varshavsky

Research.com Recognitions

• 2005 - Member of Academia Europaea
• 2002 - Fellow of the American Association for the Advancement of Science (AAAS)
• 1995 - Member of the National Academy of Sciences
• 1987 - Fellow of the American Academy of Arts and Sciences

Overview

Best Publications

• In Vivo Half-Life of a Protein is a Function of its Amino-Terminal Residue

  Andreas Bachmair;Daniel Finley;Alexander Varshavsky

  2506
  Citations

• A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein.

  Vincent Chau;John W. Tobias;Andreas Bachmair;Andreas Bachmair;David Marriott

  1972
  Citations

• The N-end rule: functions, mysteries, uses

  Alexander Varshavsky

  1290
  Citations

• A proteolytic pathway that recognizes ubiquitin as a degradation signal.

  Erica S. Johnson;Philip C.M. Ma;Irene M. Ota;Alexander Varshavsky

  1180
  Citations

• The yeast polyubiquitin gene is essential for resistance to high temperatures, starvation, and other stresses

  Daniel Finley;Engin Özkaynak;Alexander Varshavsky

  1151
  Citations

• Split ubiquitin as a sensor of protein interactions in vivo

  Nils Johnsson;Alexander Varshavsky

  1134
  Citations

• The yeast DNA repair gene RAD6 encodes a ubiquitin-conjugating enzyme

  Stefan Jentsch;John P. McGrath;Alexander Varshavsky

  999
  Citations

• The tails of ubiquitin precursors are ribosomal proteins whose fusion to ubiquitin facilitates ribosome biogenesis.

  Daniel Finley;Bonnie Bartel;Alexander Varshavsky

  908
  Citations

• The N-end rule pathway and regulation by proteolysis

  Alexander Varshavsky

  890
  Citations

• N-Terminal Acetylation of Cellular Proteins Creates Specific Degradation Signals

  Cheol-Sang Hwang;Anna Shemorry;Alexander Varshavsky

  882
  Citations

• Basic Medical Research Award. The ubiquitin system.

  Avram Hershko;Aaron Ciechanover;Alexander Varshavsky

  880
  Citations

• The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein.

  John P. McGrath;Alexander Varshavsky

  832
  Citations

• The ubiquitin system

  Alexander Varshavsky

  830
  Citations

• A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome

  François Strauss;Alexander Varshavsky

  816
  Citations

• Mapping proteinDNA interactions in vivo with formaldehyde: Evidence that histone H4 is retained on a highly transcribed gene

  Mark J. Solomon;Pamela L. Larsen;Alexander Varshavsky

  772
  Citations

• Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

  Aaron Ciechanover;Daniel Finley;Alexander Varshavsky

  745
  Citations

• The N-end rule in bacteria.

  John W. Tobias;Thomas E. Shrader;Gabrielle Rocap;Alexander Varshavsky

  730
  Citations

• Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85

  Daniel Finley;Aaron Ciechanover;Alexander Varshavsky

  726
  Citations

• The N-end Rule

  A Varshavsky

  721
  Citations

• Ubiquitin-mediated protein degradation: The early days The ubiquitin system

  Avram Hershko;Aaron Ciechanover;Alexander Varshavsky

  0
  Citations