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Biology and Biochemistry

D-Index
57
Citations
12941
World Ranking
13732
National Ranking
162

Overview

Yong Tae Kwon is affiliated with Seoul National University in South Korea and focuses their research on the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their subfields include Molecular Biology, Epidemiology, Cell Biology, Cancer Research, and Immunology.

The scientist's work addresses several main topics, notably:

  • Autophagy in Disease and Therapy
  • Ubiquitin and proteasome pathways
  • Endoplasmic Reticulum Stress and Disease
  • Protein Degradation and Inhibitors
  • Toxoplasma gondii Research Studies
  • Cancer, Hypoxia, and Metabolism
  • Epigenetics and DNA Methylation

Their recent papers include the following:

  • 'The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system', 2022, published in Nature Communications
  • 'p62-Induced Cancer-Associated Fibroblast Activation via the Nrf2-ATF6 Pathway Promotes Lung Tumorigenesis', 2021, published in Cancers
  • 'Targeted degradation of ⍺-synuclein aggregates in Parkinson's disease using the AUTOTAC technology', 2023, published in Molecular Neurodegeneration
  • 'Chemical modulation of SQSTM1/p62-mediated xenophagy that targets a broad range of pathogenic bacteria', 2022, published in Autophagy
  • 'Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes', 2020, published in Proceedings of the National Academy of Sciences

Yong Tae Kwon often collaborates with other researchers; frequent co-authors include Chang Hoon Ji, Su Kim, Ah Jung Heo, Bo Yeon Kim, and Min Ju Lee.

The scientist frequently publishes in specific venues, with multiple works appearing in:

  • Proceedings of the National Academy of Sciences
  • Autophagy
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cell Reports

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies

    Aaron Ciechanover;Yong T.ae Kwon

  • The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy

    Yong Tae Kwon;Aaron Ciechanover;Aaron Ciechanover

  • The N-End Rule Pathway

    Takafumi Tasaki;Shashikanth M. Sriram;Kyong Soo Park;Yong Tae Kwon

  • A Family of Mammalian E3 Ubiquitin Ligases That Contain the UBR Box Motif and Recognize N-Degrons

    Takafumi Tasaki;Lubbertus C. F. Mulder;Akihiro Iwamatsu;Min Jae Lee

  • Effects of low dose quercetin: cancer cell-specific inhibition of cell cycle progression.

    Jae-Hoon Jeong;Jee Young An;Yong Tae Kwon;Juong G. Rhee

  • An Essential Role of N-Terminal Arginylation in Cardiovascular Development

    Yong Tae Kwon;Anna S. Kashina;Ilia V. Davydov;Rong-Gui Hu

  • Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells

    Seog Young Kim;Jin Wook Kang;Xinxin Song;Bo Kyoung Kim

  • Crosstalk and Interplay between the Ubiquitin-Proteasome System and Autophagy.

    Chang Hoon Ji;Yong Tae Kwon

  • RGS4 and RGS5 are in vivo substrates of the N-end rule pathway

    Min Jae Lee;Takafumi Tasaki;Kayoko Moroi;Jee Young An

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome).

    Martin Zenker;Julia Mayerle;Markus M Lerch;Andreas Tagariello

  • Protein Quality Control by Molecular Chaperones in Neurodegeneration

    Aaron Ciechanover;Aaron Ciechanover;Yong Tae Kwon

  • p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis

    Hyunjoo Cha-Molstad;Ji Eun Yu;Ji Eun Yu;Zhiwei Feng;Su Hyun Lee

  • p62- and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome

    Victoria Cohen-Kaplan;Ido Livneh;Noa Avni;Bertrand Fabre

  • Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.

    Hyunjoo Cha-Molstad;Ki Sa Sung;Joonsung Hwang;Kyoung A. Kim

  • Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats.

    Stewart H. Lecker;Vered Solomon;S. Russ Price;Yong Tae Kwon

  • The mouse and human genes encoding the recognition component of the N-end rule pathway.

    Yong Tae Kwon;Yuval Reiss;Victor A. Fried;Avram Hershko

Frequent Co-Authors

Aaron Ciechanover
Aaron Ciechanover Technion – Israel Institute of Technology
Yong J. Lee
Yong J. Lee University of Pittsburgh
Alexander Varshavsky
Alexander Varshavsky California Institute of Technology
David L. Bartlett
David L. Bartlett University of Pittsburgh
Dong-Hyun Kim
Dong-Hyun Kim Kyung Hee University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Sergio Lavandero
Sergio Lavandero University of Chile
Gerald W. Dorn
Gerald W. Dorn Washington University in St. Louis
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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