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D-Index & Metrics

Molecular Biology

D-Index
64
Citations
21346
World Ranking
1709
National Ranking
863

Overview

Yong J. Lee is affiliated with the University of Pittsburgh in the United States and has a research focus primarily in biochemistry, genetics, molecular biology, and medicine. Their work spans several subfields including molecular biology, pulmonary and respiratory medicine, immunology, oncology, and cell biology.

The scientist's recent publications cover a range of topics related to cell death mechanisms, ferroptosis, disease regulation, and cellular stress responses. Notable papers include:

  • "BAX-dependent mitochondrial pathway mediates the crosstalk between ferroptosis and apoptosis" (2020, APOPTOSIS)
  • "Diverse functions of cytochrome c in cell death and disease" (2024, Cell Death and Differentiation)
  • "The anti-fibrotic drug pirfenidone inhibits liver fibrosis by targeting the small oxidoreductase glutaredoxin-1" (2021, Science Advances)
  • "Ferroptotic agent-induced endoplasmic reticulum stress response plays a pivotal role in the autophagic process outcome" (2020, Journal of Cellular Physiology)
  • "The emerging role of selenium metabolic pathways in cancer: New therapeutic targets for cancer" (2021, Journal of Cellular Biochemistry)

Their research addresses key areas such as ferroptosis and cancer prognosis, cell death mechanisms and regulation, endoplasmic reticulum stress and disease, inflammatory bowel disease, autophagy in disease and therapy, phagocytosis and immune regulation, and microRNA in disease regulation.

Frequent publication venues for Yong J. Lee include:

  • Journal of Cellular Physiology
  • Journal of Cellular Biochemistry
  • Journal of Crohn's and Colitis
  • APOPTOSIS
  • Cancer Medicine

Collaboration is a notable aspect of their work. Frequent co-authors include:

  • Haroon A. Choudry
  • Xinxin Song
  • Kalimuthu Kalishwaralal
  • Sarah Helmueller
  • Xu Luo

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Sulforaphane-induced Cell Death in Human Prostate Cancer Cells Is Initiated by Reactive Oxygen Species

    Shivendra V. Singh;Sanjay K. Srivastava;Sunga Choi;Karen L. Lew

  • S-Glutathiolation of Ras Mediates Redox-sensitive Signaling by Angiotensin II in Vascular Smooth Muscle Cells

    Takeshi Adachi;David R. Pimentel;Tyler Heibeck;Xiuyun Hou

  • Glucose deprivation-induced oxidative stress in human tumor cells. A fundamental defect in metabolism?

    Douglas R. Spitz;Julia E. Sim;Lisa A. Ridnour;Sandra S. Galoforo

  • Effects of low dose quercetin: cancer cell-specific inhibition of cell cycle progression.

    Jae-Hoon Jeong;Jee Young An;Yong Tae Kwon;Juong G. Rhee

  • Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells

    Seog Young Kim;Jin Wook Kang;Xinxin Song;Bo Kyoung Kim

  • Role of glutaredoxin in metabolic oxidative stress. Glutaredoxin as a sensor of oxidative stress mediated by H2O2.

    Jae J. Song;Juong G. Rhee;Mohan Suntharalingam;Susan A. Walsh

  • Glucose Deprivation-induced Cytotoxicity and Alterations in Mitogen-activated Protein Kinase Activation Are Mediated by Oxidative Stress in Multidrug-resistant Human Breast Carcinoma Cells

    Yong J. Lee;Sandra S. Galoforo;Christine M. Berns;Jenn C. Chen

  • Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2.

    Dong Xiao;Sunga Choi;Daniel E Johnson;Victor G Vogel

  • Ferroptosis-Induced Endoplasmic Reticulum Stress: Cross-talk between Ferroptosis and Apoptosis.

    Young-Sun Lee;Dae-Hee Lee;Dae-Hee Lee;Haroon A. Choudry;David L. Bartlett

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Differential role of glutaredoxin and thioredoxin in metabolic oxidative stress-induced activation of apoptosis signal-regulating kinase 1.

    Jae J Song;Yong J Lee

  • Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis

    Sunil S. Metkar;Baikun Wang;Michelle L. Ebbs;Jin H. Kim

  • Quercetin augments TRAIL-induced apoptotic death: Involvement of the ERK signal transduction pathway

    Young-Ho Kim;Dae-Hee Lee;Jae-Hoon Jeong;Zong Sheng Guo

  • Tissue Inhibitor of Metalloproteinase-1 Protects Human Breast Epithelial Cells from Extrinsic Cell Death: A Potential Oncogenic Activity of Tissue Inhibitor of Metalloproteinase-1

    Xu Wen Liu;Marcus E. Taube;Ki Kyung Jung;Zhong Dong

  • Galectin-3 Protects Human Breast Carcinoma Cells against Nitric Oxide-Induced Apoptosis Implication of Galectin-3 Function during Metastasis

    Bong Ki Moon;Bong Ki Moon;Yong J. Lee;Paul Battle;J. Milburn Jessup

  • Role of p53, PUMA, and Bax in wogonin-induced apoptosis in human cancer cells

    Dae-Hee Lee;Clifford Kim;Lin Zhang;Yong J. Lee

  • Differential, stage-dependent expression of Hsp70, Hsp110 and Bcl-2 in colorectal cancer.

    Tae Sook Hwang;Hye Seung Han;Hyo Kyoung Choi;Yong J Lee

  • Role of Bax in quercetin-induced apoptosis in human prostate cancer cells.

    Dae-Hee Lee;Miroslaw Szczepanski;Yong J. Lee

Frequent Co-Authors

David L. Bartlett
David L. Bartlett University of Pittsburgh
Yong Tae Kwon
Yong Tae Kwon Seoul National University
Douglas R. Spitz
Douglas R. Spitz University of Iowa
Yun-Sil Lee
Yun-Sil Lee Ewha Womans University
William C. Dewey
William C. Dewey University of California, San Francisco
Herbert J. Zeh
Herbert J. Zeh The University of Texas Southwestern Medical Center
Shivendra V. Singh
Shivendra V. Singh University of Pittsburgh
Andrew A. Amoscato
Andrew A. Amoscato University of Pittsburgh
Aaron Ciechanover
Aaron Ciechanover Technion – Israel Institute of Technology
Evelina Gatti
Evelina Gatti Aix-Marseille University

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