What is he best known for?
The fields of study he is best known for:
Douglas R. Spitz focuses on Oxidative stress, Molecular biology, Biochemistry, Cell biology and Superoxide dismutase.
His Oxidative stress study is concerned with the larger field of Internal medicine.
The study incorporates disciplines such as Cell culture, DNA damage, Catalase, Reactive oxygen species and Cytochrome c in addition to Molecular biology.
His work on Glutathione, Mitochondrion, Cysteine and Hydrogen peroxide as part of general Biochemistry research is often related to Hsp27, thus linking different fields of science.
His work carried out in the field of Cell biology brings together such families of science as Cell cycle and Programmed cell death.
His research in Superoxide dismutase focuses on subjects like Oncogene, which are connected to SIRT3.
His most cited work include:
- A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation (795 citations)
- Sirt3-Mediated Deacetylation of Evolutionarily Conserved Lysine 122 Regulates MnSOD Activity in Response to Stress (638 citations)
- SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. (592 citations)
What are the main themes of his work throughout his whole career to date?
Douglas R. Spitz mainly focuses on Oxidative stress, Biochemistry, Cancer research, Molecular biology and Glutathione.
His study in Oxidative stress is interdisciplinary in nature, drawing from both Toxicity, Cytotoxicity and Cell biology.
His work in Biochemistry is not limited to one particular discipline; it also encompasses Pharmacology.
In his study, Cell killing is strongly linked to Cancer cell, which falls under the umbrella field of Cancer research.
His Molecular biology research is multidisciplinary, incorporating elements of Cell culture, Reactive oxygen species, Superoxide dismutase and Catalase.
He combines subjects such as DNA damage and Mitochondrion with his study of Reactive oxygen species.
He most often published in these fields:
- Oxidative stress (35.97%)
- Biochemistry (26.98%)
- Cancer research (25.34%)
What were the highlights of his more recent work (between 2017-2021)?
- Cancer research (25.34%)
- Oxidative stress (35.97%)
- Cancer cell (17.71%)
In recent papers he was focusing on the following fields of study:
His primary areas of investigation include Cancer research, Oxidative stress, Cancer cell, Cancer and Radiation therapy.
Douglas R. Spitz interconnects Cell culture, Superoxide dismutase, Superoxide and Glutathione in the investigation of issues within Cancer research.
His Oxidative stress study combines topics from a wide range of disciplines, such as Progenitor cell, Melanoma, Toxicity, Cell biology and In vivo.
His Toxicity research is multidisciplinary, relying on both Vitamin C and Biochemistry.
His Biochemistry study integrates concerns from other disciplines, such as Redox and Colorectal cancer.
In general Cell biology, his work in Mitochondrion and Reactive oxygen species is often linked to Mitochondrial pyruvate transport and Prenatal stress linking many areas of study.
Between 2017 and 2021, his most popular works were:
- Targeting Breast Cancer Stem Cell State Equilibrium through Modulation of Redox Signaling. (107 citations)
- An integrated physico-chemical approach for explaining the differential impact of FLASH versus conventional dose rate irradiation on cancer and normal tissue responses. (66 citations)
- Lymph protects metastasizing melanoma cells from ferroptosis (56 citations)
In his most recent research, the most cited papers focused on:
His scientific interests lie mostly in Cancer research, Oxidative stress, Cancer, Cancer cell and Radiation therapy.
The various areas that Douglas R. Spitz examines in his Cancer research study include GPX4, Gemcitabine, Glutathione and Citric acid cycle.
His work deals with themes such as Cell biology, Toxicity and Pharmacology, which intersect with Oxidative stress.
Reactive oxygen species is closely connected to Transferrin in his research, which is encompassed under the umbrella topic of Cell biology.
His Cancer study combines topics from a wide range of disciplines, such as Transport protein, Superoxide dismutase, Gene expression and Detoxification.
Many of his studies involve connections with topics such as Endocrinology and Internal medicine.
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