D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 63 Citations 11,370 224 World Ranking 6755 National Ranking 3136

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

Frederick E. Domann mainly investigates Molecular biology, Biochemistry, Reactive oxygen species, Superoxide dismutase and DNA methylation. His studies deal with areas such as Oxidative stress, Catalase, Cancer cell, Mutation and Binding site as well as Molecular biology. His Biochemistry study frequently draws connections between related disciplines such as Cell biology.

His study in Reactive oxygen species is interdisciplinary in nature, drawing from both Cell cycle, Cyclin D1, Cyclin and Signal transduction. His research integrates issues of Dicoumarol, NADH Dehydrogenase and Superoxide in his study of Superoxide dismutase. His work deals with themes such as Chromatin, Cancer research and Epigenetics, which intersect with DNA methylation.

His most cited work include:

  • Role for DNA methylation in the control of cell type specific maspin expression. (400 citations)
  • Disruption of an AP-2 alpha binding site in an IRF6 enhancer is associated with cleft lip (348 citations)
  • α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II (216 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Cancer research, Molecular biology, DNA methylation, Cell biology and Epigenetics. His biological study spans a wide range of topics, including Cancer cell, Cancer, Metastasis, Carcinogenesis and Pathology. His studies in Molecular biology integrate themes in fields like Cell culture, Transcription factor, Gene expression, Gene and Cell growth.

The concepts of his DNA methylation study are interwoven with issues in Chromatin, Regulation of gene expression and Methylation. His Epigenetics research incorporates elements of Histone, Maspin, Gene silencing and Epigenome. His Reactive oxygen species research is multidisciplinary, incorporating elements of Oxidative stress and Mitochondrion.

He most often published in these fields:

  • Cancer research (37.61%)
  • Molecular biology (30.53%)
  • DNA methylation (17.70%)

What were the highlights of his more recent work (between 2012-2021)?

  • Cancer research (37.61%)
  • Cell biology (17.26%)
  • Epigenetics (15.04%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Cancer research, Cell biology, Epigenetics, Molecular biology and Oxidative stress. The study incorporates disciplines such as Cancer cell, Cancer, Metastasis, Carcinogenesis and Pathology in addition to Cancer research. His Cell biology study incorporates themes from Reprogramming, Transcription factor and SOD2.

The various areas that Frederick E. Domann examines in his Epigenetics study include Histone and DNA methylation. Frederick E. Domann has included themes like Chromatin and Gene silencing in his DNA methylation study. His Molecular biology research is multidisciplinary, relying on both Cell culture, Mitochondrial matrix and Extracellular superoxide dismutase.

Between 2012 and 2021, his most popular works were:

  • O2⋅− and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate (178 citations)
  • Mitochondria, energetics, epigenetics, and cellular responses to stress. (139 citations)
  • Limitations of oxygen delivery to cells in culture: An underappreciated problem in basic and translational research (94 citations)

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Role for DNA methylation in the control of cell type specific maspin expression.

Bernard W. Futscher;Marc M. Oshiro;Ryan J. Wozniak;Nicholas Holtan.
Nature Genetics (2002)

574 Citations

Disruption of an AP-2 alpha binding site in an IRF6 enhancer is associated with cleft lip

Fedik Rahimov;Mary L Marazita;Axel Visel;Margaret E Cooper.
Nature Genetics (2008)

563 Citations

O2⋅− and H2O2-Mediated Disruption of Fe Metabolism Causes the Differential Susceptibility of NSCLC and GBM Cancer Cells to Pharmacological Ascorbate

Joshua D. Schoenfeld;Zita A. Sibenaller;Kranti A. Mapuskar;Brett A. Wagner.
Cancer Cell (2017)

301 Citations

α-Tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II

Lan-Feng Dong;Pauline Low;Jeffrey C. Dyason;Xiu-Fang Wang.
Oncogene (2008)

299 Citations

Identification of a Functional Peroxisome Proliferator-Activated Receptor Response Element in the Rat Catalase Promoter

Geoffrey D. Girnun;Frederick E. Domann;Steven A. Moore;Mike E. C. Robbins.
Molecular Endocrinology (2002)

286 Citations

An epigenetic perspective on the free radical theory of development

Michael J Hitchler;Frederick E Domann.
Free Radical Biology and Medicine (2007)

269 Citations

The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma.

Joseph J. Cullen;Christine Weydert;Marilyn M. Hinkhouse;Justine Ritchie.
Cancer Research (2003)

268 Citations

Epigenetic silencing of maspin gene expression in human breast cancers.

Frederick E. Domann;Judd C. Rice;Mary J.C. Hendrix;Bernard W. Futscher.
International Journal of Cancer (2000)

241 Citations

The redox basis of epigenetic modifications: from mechanisms to functional consequences.

Anthony R. Cyr;Frederick E. Domann.
Antioxidants & Redox Signaling (2011)

223 Citations

Mitochondria, energetics, epigenetics, and cellular responses to stress.

Daniel T. Shaughnessy;Kimberly McAllister;Leroy Worth;Astrid C. Haugen.
Environmental Health Perspectives (2014)

218 Citations

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