G. Tim Bowden

Overview

Best Publications

• Activation of the mouse cellular Harvey- ras gene in chemically induced benign skin papillomas

  Allan Balmain;Martin Ramsden;George T. Bowden;John Smith

  760
  Citations

• Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling

  G. Tim Bowden

  521
  Citations

• UVA-mediated activation of signaling pathways involved in skin tumor promotion and progression

  Michael A Bachelor;G.Tim Bowden

  350
  Citations

• Expression of metalloproteinase genes in human prostate cancer.

  M. Siadat Pajouh;R. B. Nagle;R. Breathnach;J. S. Finch

  312
  Citations

• Increased ROS levels contribute to elevated transcription factor and MAP kinase activities in malignantly progressed mouse keratinocyte cell lines.

  Ashok Gupta;Sabine F. Rosenberger;G. Tim Bowden

  277
  Citations

• Role of p38 MAP kinases and ERK in mediating ultraviolet-B induced cyclooxygenase-2 gene expression in human keratinocytes

  Weixing Chen;Qingbo Tang;Melissa S Gonzales;G Tim Bowden

  254
  Citations

• Raf and MEK protein kinases are direct molecular targets for the chemopreventive effect of quercetin, a major flavonol in red wine.

  Ki Won Lee;Nam Joo Kang;Nam Joo Kang;Yong-Seok Heo;Evgeny A. Rogozin

  245
  Citations

• Myricetin Suppresses UVB-Induced Skin Cancer by Targeting Fyn

  Sung Keun Jung;Ki Won Lee;Sanguine Byun;Nam Joo Kang;Nam Joo Kang

  195
  Citations

• Inhibition of ultraviolet B–induced c-fos gene expression and p38 mitogen-activated protein kinase activation by (-)-epigallocatechin gallate in a human keratinocyte cell line

  Weixing Chen;Zigang Dong;Susanne Valcic;Barbara N. Timmermann

  192
  Citations

• Inhibition of Ultraviolet B-induced Activator Protein-1 (AP-1) Activity by Aspirin in AP-1-Luciferase Transgenic Mice

  Chuanshu Huang;Wei-Ya Ma;David Hanenberger;Margot P. Cleary

  188
  Citations

• Secreted phosphoprotein mRNA is induced during multi-stage carcinogenesis in mouse skin and correlates with the metastatic potential of murine fibroblasts.

  Craig Am;Bowden Gt;Chambers Af;Spearman Ma

  171
  Citations

• RING protein Trim32 associated with skin carcinogenesis has anti-apoptotic and E3-ubiquitin ligase properties.

  Elizabeth J. Horn;Elizabeth J. Horn;Amador Albor;Yuangang Liu;Sally El-Hizawi

  168
  Citations

• Ultraviolet B-induced Activated Protein-1 Activation Does Not Require Epidermal Growth Factor Receptor but Is Blocked by a Dominant Negative PKCλ/ι

  Chuanshu Huang;Wei-ya Ma;G. Tim Bowden;Zigang Dong

  164
  Citations

• Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors

  M A Nelson;B W Futscher;T Kinsella;J Wymer

  163
  Citations

• DIRECT EVIDENCE FOR AN IMPORTANT ROLE OF SPHINGOMYELINASE IN ULTRAVIOLET-INDUCED ACTIVATION OF C-JUN N-TERMINAL KINASE

  Chuanshu Huang;Wei Ya Ma;Min Ding;G. Tim Bowden

  159
  Citations

• Myricetin is a novel natural inhibitor of neoplastic cell transformation and MEK1

  Ki Won Lee;Ki Won Lee;Nam Joo Kang;Nam Joo Kang;Evgeny A. Rogozin;Honggyum Kim

  149
  Citations

• Expression pattern of a gene for a secreted metalloproteinase during late stages of tumor progression.

  Lawrence E. Ostrowski;Joanne Finch;Peter Krieg;Lynn Matrisian

  149
  Citations

• Inhibition of Ultraviolet B–Induced AP‐1 Activation by Theaflavins From Black Tea

  Masaaki Nomura;Wei Ya Ma;Chuanshu Huang;Chung S. Yang

  143
  Citations

• Expression of dominant negative c-jun inhibits ultraviolet B-induced squamous cell carcinoma number and size in an SKH-1 hairless mouse model.

  Simon J. Cooper;Jacalyn MacGowan;James Ranger-Moore;Matthew R. Young

  142
  Citations

• UVB irradiation-induced activator protein-1 activation correlates with increased c-fos gene expression in a human keratinocyte cell line.

  Weixing Chen;Alexander H. Borchers;Zigang Dong;Marianne B. Powell

  135
  Citations