What is he best known for?
The fields of study he is best known for:
Cristian Coarfa focuses on Genetics, Cancer research, DNA methylation, Gene expression profiling and microRNA.
His study on Genetics is mostly dedicated to connecting different topics, such as Computational biology.
His Cancer research research includes themes of Cancer, Coactivator, Signal transduction, Ubiquitin ligase and Androgen receptor.
His research integrates issues of Kataegis, Mitochondrial DNA, Point mutation and Somatic cell in his study of DNA methylation.
His work deals with themes such as Ribonuclease III, Molecular biology, Messenger RNA, Regulation of gene expression and Gene isoform, which intersect with microRNA.
His Human genetics research includes elements of Epigenomics, ATAC-seq and Epigenome.
His most cited work include:
- Integrative analysis of 111 reference human epigenomes (3776 citations)
- Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications (572 citations)
- Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood (519 citations)
What are the main themes of his work throughout his whole career to date?
Cristian Coarfa mostly deals with Cancer research, Genetics, Cell biology, Internal medicine and microRNA.
His Cancer research study integrates concerns from other disciplines, such as Carcinogenesis, Cancer, Breast cancer, Prostate cancer and Transcriptome.
His Genetics study frequently draws connections to adjacent fields such as Computational biology.
His work carried out in the field of Cell biology brings together such families of science as Phenotype, Transcription factor and Cell growth.
His Internal medicine study combines topics in areas such as Gastroenterology, Endocrinology, Oncology and Metabolomics.
As a part of the same scientific study, Cristian Coarfa usually deals with the DNA methylation, concentrating on Epigenetics and frequently concerns with Human genetics.
He most often published in these fields:
- Cancer research (40.73%)
- Genetics (14.59%)
- Cell biology (13.37%)
What were the highlights of his more recent work (between 2019-2021)?
- Cancer research (40.73%)
- Cell biology (13.37%)
- Internal medicine (13.07%)
In recent papers he was focusing on the following fields of study:
His scientific interests lie mostly in Cancer research, Cell biology, Internal medicine, Transcriptome and Endocrinology.
His Cancer research research incorporates elements of Cancer, Metastasis, Metastatic breast cancer, Estrogen receptor alpha and Androgen receptor.
His Cell biology study also includes fields such as
- Transcription factor which is related to area like Cell growth and Transcription,
- Histone that intertwine with fields like Reprogramming, Epigenomics, Structure–activity relationship and Biological activity,
- Histone methyltransferase, which have a strong connection to SETD2, Genome instability and Chromatin remodeling,
- Spindle apparatus together with Microtubule.
His Internal medicine research is multidisciplinary, incorporating perspectives in microRNA and Oncology.
Immune system is a subfield of Genetics that he investigates.
His Methylation study combines topics in areas such as Computational biology and DNA methylation.
Between 2019 and 2021, his most popular works were:
- Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy. (29 citations)
- Exercise restores dysregulated gene expression in a mouse model of arrhythmogenic cardiomyopathy (16 citations)
- Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture (14 citations)
In his most recent research, the most cited papers focused on:
His main research concerns Cancer research, Internal medicine, Cell biology, Immune system and Endocrinology.
His Cancer research study combines topics from a wide range of disciplines, such as Cancer, Breast cancer, Flux, Dilated cardiomyopathy and Bromodomain.
His research in Breast cancer intersects with topics in Transcription factor, microRNA, Metastasis, Disease and Regulation of gene expression.
His study in the field of Prostate cancer, Androgen, Androgen deprivation therapy and Adverse effect is also linked to topics like Clinical endpoint.
His work carried out in the field of Cell biology brings together such families of science as Hypothalamus, Histone, Estrogen receptor and Transcriptome.
His research integrates issues of Epigenomics, EGR1, Epigenesis, Rat model and Epigenome in his study of Transcriptome.
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