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Biology and Biochemistry

D-Index
50
Citations
24377
World Ranking
17391
National Ranking
7145

Overview

Robert A. Waterland is affiliated with Baylor College of Medicine in the United States. Their research primarily focuses on the field of Biochemistry, Genetics, and Molecular Biology, with particular expertise in Molecular Biology, Genetics, Pediatrics, Perinatology and Child Health, Nutrition and Dietetics, and to a lesser extent Sociology and Political Science.

The scientist's work addresses key topics including:

  • Epigenetics and DNA Methylation
  • Birth, Development, and Health
  • RNA modifications and cancer
  • Genetic Syndromes and Imprinting
  • Infant Nutrition and Health
  • Cancer-related gene regulation
  • Genetic Associations and Epidemiology

Frequent collaborators in Robert A. Waterland's research network include Chathura Gunasekara, Cristian Coarfa, Maria S. Baker, Eleonora Laritsky, and Harry A. Mackay. These collaborations contribute to studies that appear consistently in several publication venues.

Their research has been published extensively in venues such as UNC Libraries, Genome Biology, bioRxiv (Cold Spring Harbor Laboratory), Science Advances, and Advances in Nutrition.

Recent papers by Robert A. Waterland include the following:

  • Can Children Catch up from the Consequences of Undernourishment? Evidence from Child Linear Growth, Developmental Epigenetics, and Brain and Neurocognitive Development, 2020, Advances in Nutrition
  • Identification of cell type-specific methylation signals in bulk whole genome bisulfite sequencing data, 2020, Genome Biology
  • Systemic interindividual epigenetic variation in humans is associated with transposable elements and under strong genetic control, 2023, Genome Biology
  • A machine learning case-control classifier for schizophrenia based on DNA methylation in blood, 2021, Translational Psychiatry
  • Perfluorooctanoic acid (PFOA) or perfluorooctane sulfonate (PFOS) and DNA methylation in newborn dried blood spots in the Upstate KIDS cohort, 2020, Environmental Research

The research contributions emphasize epigenetic regulation mechanisms and their implications in human development, nutrition, neurocognitive health, and disease states including schizophrenia and cancer. Methodologically, the work frequently involves DNA methylation analysis and bioinformatics approaches applied to large-scale genomic data.

Best Publications

  • Integrative analysis of 111 reference human epigenomes

    Anshul Kundaje;Wouter Meuleman;Wouter Meuleman;Jason Ernst

  • Transposable elements: targets for early nutritional effects on epigenetic gene regulation.

    Robert A. Waterland;Randy L. Jirtle

  • Maternal Genistein Alters Coat Color and Protects Avy Mouse Offspring from Obesity by Modifying the Fetal Epigenome

    Dana C. Dolinoy;Jennifer R. Weidman;Robert A. Waterland;Randy L. Jirtle

  • Epigenetic epidemiology of the developmental origins hypothesis.

    Robert A. Waterland;Karin B. Michels

  • Early nutrition, epigenetic changes at transposons and imprinted genes, and enhanced susceptibility to adult chronic diseases

    Robert A Waterland;Randy L Jirtle

  • Potential mechanisms of metabolic imprinting that lead to chronic disease

    Robert A Waterland;Cutberto Garza

  • Child health, developmental plasticity, and epigenetic programming.

    Z. Hochberg;Robert Feil;M. Constancia;M. Fraga

  • Comparison of sequencing-based methods to profile DNA methylation and identification of monoallelic epigenetic modifications

    R Alan Harris;Ting Wang;Cristian Coarfa;Raman P. Nagarajan

  • Maternal methyl supplements increase offspring DNA methylation at Axin fused

    Robert A. Waterland;Dana C. Dolinoy;Juan Ru Lin;Charlotte A. Smith

  • Maternal nutrition at conception modulates DNA methylation of human metastable epialleles

    Paula Dominguez-Salas;Sophie E. Moore;Maria S. Baker;Andrew W. Bergen

  • Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters

    Lanlan Shen;Yutaka Kondo;Yi Guo;Jiexin Zhang

  • Season of Conception in Rural Gambia Affects DNA Methylation at Putative Human Metastable Epialleles

    Robert A. Waterland;Richard Kellermayer;Eleonora Laritsky;Pura Rayco-Solon

  • Methyl donor supplementation prevents transgenerational amplification of obesity

    R. A. Waterland;Michael Travisano;Michael Travisano;K. G. Tahiliani;M. T. Rached

  • Post-weaning diet affects genomic imprinting at the insulin-like growth factor 2 (Igf2) locus

    Robert A. Waterland;Juan-Ru Lin;Charlotte A. Smith;Randy L. Jirtle

  • Assessing the Effects of High Methionine Intake on DNA Methylation

    Robert A. Waterland

  • Tumor suppressor gene inactivation during cadmium-induced malignant transformation of human prostate cells correlates with overexpression of de novo DNA methyltransferase.

    Lamia Benbrahim-Tallaa;Robert A. Waterland;Anna L. Dill;Mukta M. Webber

  • Diet-induced hypermethylation at agouti viable yellow is not inherited transgenerationally through the female

    Robert A. Waterland;Michael Travisano;Kajal G. Tahiliani

  • Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation

    Lamia Benbrahim-Tallaa;Robert A. Waterland;Miroslav Styblo;William E. Achanzar

  • Epigenetic regulation in murine offspring as a novel mechanism for transmaternal asthma protection induced by microbes

    Stephanie Brand;René Teich;Tanja Dicke;Hani Harb

  • Methods of DNA methylation analysis.

    Lanlan Shen;Robert A Waterland

Frequent Co-Authors

Cristian Coarfa
Cristian Coarfa Baylor College of Medicine
Andrew M. Prentice
Andrew M. Prentice London School of Hygiene & Tropical Medicine
Michael Travisano
Michael Travisano University of Minnesota
Rui Chen
Rui Chen Capital Medical University
Karin B. Michels
Karin B. Michels University of California, Los Angeles
R. Alan Harris
R. Alan Harris Baylor College of Medicine
Bradley E. Bernstein
Bradley E. Bernstein Broad Institute
Aleksandar Milosavljevic
Aleksandar Milosavljevic Baylor College of Medicine
Moshe Szyf
Moshe Szyf McGill University
Zdenko Herceg
Zdenko Herceg International Agency For Research On Cancer

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