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Hilary K. Finucane

Hilary K. Finucane

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
49937
World Ranking
11640
National Ranking
5008

Overview

Hilary K. Finucane is affiliated with Harvard University in the United States. Their research primarily focuses on the field of Biochemistry, Genetics and Molecular Biology, with specific emphasis on Molecular Biology, Genetics, Immunology, Physiology, and Cancer Research. The central topics of their scholarly work include Genetic Associations and Epidemiology, Bioinformatics and Genomic Networks, RNA Research and Splicing, RNA modifications and cancer, Genetic Mapping and Diversity in Plants and Animals, Genetic and phenotypic traits in livestock, as well as Genomics and Rare Diseases.

Finucane has contributed to multiple recent scientific papers, including:

  • FinnGen provides genetic insights from a well-phenotyped isolated population (2023, Nature)
  • Mapping the human genetic architecture of COVID-19 (2021, Nature)
  • Genome-wide enhancer maps link risk variants to disease genes (2021, Nature)
  • Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants (2022, Nature Genetics)
  • FinnGen: Unique genetic insights from combining isolated population and national health register data (2022, bioRxiv (Cold Spring Harbor Laboratory))

Their frequent co-authors include Masahiro Kanai, Jacob C. Ulirsch, Benjamin M. Neale, Mark J. Daly, and Wei Zhou. These collaborations reflect active engagement in multidisciplinary research networks.

Finucane's work is regularly published in several scientific venues, most notably bioRxiv (Cold Spring Harbor Laboratory), Nature Genetics, Nature, Nature Communications, and UNC Libraries. This distribution indicates a focus on high-impact journals and preprint repositories specialized in genetics and molecular biology.

Best Publications

  • LD score regression distinguishes confounding from polygenicity in genome-wide association studies :

    Brendan K Bulik-Sullivan;Po-Ru Loh;Hilary K Finucane;Stephan Ripke

  • An atlas of genetic correlations across human diseases and traits.

    Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K Finucane;Verneri Anttila;Verneri Anttila;Alexander Gusev

  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    Naomi R. Wray;Stephan Ripke;Stephan Ripke;Stephan Ripke;Manuel Mattheisen;MacIej Trzaskowski

  • Partitioning heritability by functional annotation using genome-wide association summary statistics.

    Hilary K Finucane;Hilary K Finucane;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Alexander Gusev;Gosia Trynka

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Efficient Bayesian mixed-model analysis increases association power in large cohorts

    Po-Ru Loh;George Tucker;Brendan K Bulik-Sullivan;Bjarni J Vilhjálmsson;Bjarni J Vilhjálmsson

  • Reference-based phasing using the Haplotype Reference Consortium panel.

    Po-Ru Loh;Po-Ru Loh;Petr Danecek;Pier Francesco Palamara;Pier Francesco Palamara;Christian Fuchsberger;Christian Fuchsberger

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis

    Jie Zheng;Mesut A. Erzurumluoglu;Benjamin L. Elsworth;John P. Kemp

  • Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.

    Hilary K Finucane;Hilary K Finucane;Hilary K Finucane;Yakir A Reshef;Verneri Anttila;Verneri Anttila;Kamil Slowikowski;Kamil Slowikowski;Kamil Slowikowski

  • Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

    Alexander Gusev;S. Hong Lee;Gosia Trynka;Hilary Finucane

  • Genome-wide enhancer maps link risk variants to disease genes

    Joseph Nasser;Drew T. Bergman;Charles P. Fulco;Charles P. Fulco;Philine Guckelberger;Philine Guckelberger

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Felix R. Day;Deborah J. Thompson;Hannes Helgason;Hannes Helgason;Daniel I. Chasman

  • Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

    Po-Ru Loh;Po-Ru Loh;Gaurav Bhatia;Gaurav Bhatia;Alexander Gusev;Alexander Gusev;Hilary K Finucane

  • Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.

    Steven Gazal;Hilary K Finucane;Hilary K Finucane;Hilary K Finucane;Nicholas A Furlotte;Po-Ru Loh;Po-Ru Loh

  • Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair

    Felix R. Day;Katherine S. Ruth;Deborah J Thompson;Kathryn L. Lunetta

  • Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights

    Alexander Gusev;Alexander Gusev;Nicholas Mancuso;Hyejung Won;Maria Kousi

  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

    Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Day Fr;Thompson Dj;elgason H;Chasman Di

Frequent Co-Authors

Alkes L. Price
Alkes L. Price Harvard University
Benjamin M. Neale
Benjamin M. Neale Harvard University
Po-Ru Loh
Po-Ru Loh Harvard Medical School
Alexander Gusev
Alexander Gusev Dana-Farber Cancer Institute
Steven Gazal
Steven Gazal University of Southern California
Hiltrud Brauch
Hiltrud Brauch German Cancer Research Center
Sara Lindström
Sara Lindström University of Washington
Stephan Ripke
Stephan Ripke Massachusetts General Hospital
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Eric S. Lander
Eric S. Lander Broad Institute

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