World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
50459
World Ranking
9940
National Ranking
4348

Research.com Recognitions

  • 2019 - Fellow of Alfred P. Sloan Foundation

Overview

Po-Ru Loh is affiliated with Harvard Medical School in the United States. Their primary research areas lie within Biochemistry, Genetics, and Molecular Biology, with a substantial focus on Genetics and Molecular Biology as key subfields. Additional areas of work include Cancer Research, Immunology, and Pediatrics, Perinatology and Child Health.

The scientist's research topics cover a broad range of subjects related to genetic and molecular analysis. Their main topics of investigation include:

  • Genetic Associations and Epidemiology
  • Genomic variations and chromosomal abnormalities
  • Genomics and Rare Diseases
  • Cancer Genomics and Diagnostics
  • Genetic Mapping and Diversity in Plants and Animals
  • Epigenetics and DNA Methylation
  • Genetic and phenotypic traits in livestock

Po-Ru Loh has coauthored extensively with several researchers including Steven A. McCarroll, Ronen E. Mukamel, Margaux L.A. Hujoel, Maxwell A. Sherman, and Alison R. Barton. These collaborations have contributed to a significant body of work published in multiple high-impact venues.

The scientist has a strong publication record, predominantly in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Genetics
  • Nature
  • Cell Genomics
  • Nature Communications

Selected recent publications by Po-Ru Loh include:

  • Whole-exome imputation within UK Biobank powers rare coding variant association and fine-mapping analyses, 2021, Nature Genetics
  • Monogenic and polygenic inheritance become instruments for clonal selection, 2020, Nature
  • Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection, 2021, Nature Medicine
  • Protein-coding repeat polymorphisms strongly shape diverse human phenotypes, 2021, Science
  • Clonal haematopoiesis and risk of chronic liver disease, 2023, Nature

Po-Ru Loh has received recognition as a Fellow of the Alfred P. Sloan Foundation in 2019.

Best Publications

  • Fast, sensitive and accurate integration of single-cell data with Harmony.

    Ilya Korsunsky;Nghia Millard;Jean Fan;Kamil Slowikowski

  • LD score regression distinguishes confounding from polygenicity in genome-wide association studies :

    Brendan K Bulik-Sullivan;Po-Ru Loh;Hilary K Finucane;Stephan Ripke

  • An atlas of genetic correlations across human diseases and traits.

    Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K Finucane;Verneri Anttila;Verneri Anttila;Alexander Gusev

  • Next-generation genotype imputation service and methods.

    Sayantan Das;Lukas Forer;Sebastian Schönherr;Carlo Sidore;Carlo Sidore

  • Partitioning heritability by functional annotation using genome-wide association summary statistics.

    Hilary K Finucane;Hilary K Finucane;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Alexander Gusev;Gosia Trynka

  • Efficient Bayesian mixed-model analysis increases association power in large cohorts

    Po-Ru Loh;George Tucker;Brendan K Bulik-Sullivan;Bjarni J Vilhjálmsson;Bjarni J Vilhjálmsson

  • Reference-based phasing using the Haplotype Reference Consortium panel.

    Po-Ru Loh;Po-Ru Loh;Petr Danecek;Pier Francesco Palamara;Pier Francesco Palamara;Christian Fuchsberger;Christian Fuchsberger

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.

    Hilary K Finucane;Hilary K Finucane;Hilary K Finucane;Yakir A Reshef;Verneri Anttila;Verneri Anttila;Kamil Slowikowski;Kamil Slowikowski;Kamil Slowikowski

  • Leveraging Polygenic Functional Enrichment to Improve GWAS Power

    Gleb Kichaev;Gaurav Bhatia;Po Ru Loh;Steven Gazal;Steven Gazal

  • Mixed-model association for biobank-scale datasets.

    Po-Ru Loh;Gleb Kichaev;Steven Gazal;Armin P Schoech;Armin P Schoech

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Felix R. Day;Deborah J. Thompson;Hannes Helgason;Hannes Helgason;Daniel I. Chasman

  • Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

    Nicole M Warrington;Robin N Beaumont;Momoko Horikoshi;Felix R Day

  • Genome-wide associations for birth weight and correlations with adult disease

    Momoko Horikoshi;Robin N. Beaumont;Felix R. Day;Nicole M. Warrington;Nicole M. Warrington

  • Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis

    Po-Ru Loh;Po-Ru Loh;Gaurav Bhatia;Gaurav Bhatia;Alexander Gusev;Alexander Gusev;Hilary K Finucane

  • Linkage disequilibrium-dependent architecture of human complex traits shows action of negative selection.

    Steven Gazal;Hilary K Finucane;Hilary K Finucane;Hilary K Finucane;Nicholas A Furlotte;Po-Ru Loh;Po-Ru Loh

  • Inferring Admixture Histories of Human Populations Using Linkage Disequilibrium

    Po-Ru Loh;Mark Lipson;Nick Patterson;Priya Moorjani;Priya Moorjani

  • Fast Principal-Component Analysis Reveals Convergent Evolution of ADH1B in Europe and East Asia

    Kevin J. Galinsky;Kevin J. Galinsky;Gaurav Bhatia;Po-Ru Loh;Po-Ru Loh;Stoyan Georgiev

  • Genetic Evidence for Recent Population Mixture in India

    Priya Moorjani;Kumarasamy Thangaraj;Nick Patterson;Mark Lipson

  • Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk

    Day Fr;Thompson Dj;elgason H;Chasman Di

Frequent Co-Authors

Alkes L. Price
Alkes L. Price Harvard University
Hilary K. Finucane
Hilary K. Finucane Harvard University
Nick Patterson
Nick Patterson Harvard University
Steven Gazal
Steven Gazal University of Southern California
Alexander Gusev
Alexander Gusev Dana-Farber Cancer Institute
David Reich
David Reich Harvard Medical School
Benjamin M. Neale
Benjamin M. Neale Harvard University
Steven A. McCarroll
Steven A. McCarroll Harvard University
Giulio Genovese
Giulio Genovese Broad Institute

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Po-Ru Loh

Trending Scientists

Recently Published Articles