D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 69 Citations 18,593 209 World Ranking 911 National Ranking 70

Research.com Recognitions

Awards & Achievements

2009 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Human Genetics and Molecular Medicine

Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • DNA
  • Genetics

Oliver Brüstle mainly investigates Stem cell, Embryonic stem cell, Cell biology, Neuroscience and Neural stem cell. Oliver Brüstle interconnects Cellular differentiation, Somatic cell, Immunology, Induced pluripotent stem cell and Transplantation in the investigation of issues within Stem cell. Oliver Brüstle has included themes like Neural cell and Neuroepithelial cell in his Immunology study.

His Cell biology study integrates concerns from other disciplines, such as Transcription factor and Anatomy. His Neuroscience research incorporates elements of Dorsum and Embryonic brain. His work deals with themes such as Neurogenesis, Molecular biology and Neurosphere, Adult stem cell, which intersect with Neural stem cell.

His most cited work include:

  • In vitro differentiation of transplantable neural precursors from human embryonic stem cells (1720 citations)
  • Embryonic Stem Cell-Derived Glial Precursors: A Source of Myelinating Transplants (965 citations)
  • Copy number variation and selection during reprogramming to pluripotency (795 citations)

What are the main themes of his work throughout his whole career to date?

Oliver Brüstle mostly deals with Cell biology, Stem cell, Embryonic stem cell, Induced pluripotent stem cell and Neuroscience. The concepts of his Cell biology study are interwoven with issues in Phenotype and Neurodegeneration. His Stem cell study integrates concerns from other disciplines, such as Immunology and Adult stem cell, Cellular differentiation, Embryoid body.

His work carried out in the field of Embryonic stem cell brings together such families of science as Progenitor cell, Molecular biology and Somatic cell. His Induced pluripotent stem cell research includes themes of Reprogramming, Cell, Cell type and Cell culture. His Neuroscience research includes elements of Disease and Transplantation.

He most often published in these fields:

  • Cell biology (46.36%)
  • Stem cell (40.45%)
  • Embryonic stem cell (35.00%)

What were the highlights of his more recent work (between 2015-2021)?

  • Induced pluripotent stem cell (35.91%)
  • Cell biology (46.36%)
  • Neuroscience (33.18%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Induced pluripotent stem cell, Cell biology, Neuroscience, Neural stem cell and Reprogramming. His Induced pluripotent stem cell research is multidisciplinary, relying on both Cell, Cell culture, Suspension culture and Stem cell. His work on Neuroepithelial cell is typically connected to Bioprocess as part of general Stem cell study, connecting several disciplines of science.

The Cell biology study combines topics in areas such as Alzheimer's disease, Embryonic stem cell, Neural development and Neurodegeneration. His Neuroscience research is multidisciplinary, incorporating elements of Cell morphology, Reelin, Disease and Transplantation. He has researched Neural stem cell in several fields, including Progenitor cell, microRNA, Cellular differentiation and DNA methylation.

Between 2015 and 2021, his most popular works were:

  • Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli (66 citations)
  • Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein. (64 citations)
  • Specific Inhibition of β-Secretase Processing of the Alzheimer Disease Amyloid Precursor Protein. (64 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Genetics

Oliver Brüstle mainly investigates Cell biology, Neural stem cell, Neuroscience, Induced pluripotent stem cell and Alzheimer's disease. His Neural stem cell research is multidisciplinary, incorporating perspectives in Endocrinology, Cellular differentiation, Lymphoblast, Immunology and Anatomy. The study incorporates disciplines such as Spinal muscular atrophy, SMN1, Internal medicine, Asymptomatic and Precursor cell in addition to Cellular differentiation.

His Neuroscience research incorporates elements of Synaptic plasticity, Glutamatergic and Neurotransmission. The various areas that Oliver Brüstle examines in his Induced pluripotent stem cell study include Engineering management, Neuregulin 1 and Bioinformatics. His research integrates issues of Extracellular, Biochemistry, Protein aggregation, Intracellular and Genetically modified mouse in his study of Alzheimer's disease.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

In vitro differentiation of transplantable neural precursors from human embryonic stem cells

Su-Chun Zhang;Marius Wernig;Ian D. Duncan;Oliver Brüstle.
Nature Biotechnology (2001)

2268 Citations

Embryonic Stem Cell-Derived Glial Precursors: A Source of Myelinating Transplants

Oliver Brüstle;Kimberly N. Jones;Kimberly N. Jones;Randall D. Learish;Khalad Karram.
Science (1999)

1407 Citations

Copy number variation and selection during reprogramming to pluripotency

Samer M. Hussein;Nizar N. Batada;Sanna Vuoristo;Reagan W. Ching.
Nature (2011)

1061 Citations

A rosette-type, self-renewing human ES cell-derived neural stem cell with potential for in vitro instruction and synaptic integration

Philipp Koch;Thoralf Opitz;Julius A. Steinbeck;Julia Ladewig.
Proceedings of the National Academy of Sciences of the United States of America (2009)

563 Citations

Direct Conversion of Fibroblasts into Stably Expandable Neural Stem Cells

Marc Thier;Philipp Wörsdörfer;Yenal B. Lakes;Raphaela Gorris.
Cell Stem Cell (2012)

551 Citations

Sirt1 contributes critically to the redox-dependent fate of neural progenitors

Timour Prozorovski;Ulf Schulze-Topphoff;Robert Glumm;Jan Baumgart.
Nature Cell Biology (2008)

499 Citations

In vitro-Generated Neural Precursors Participate in Mammalian Brain Development

O. Brustle;A. C. Spiro;K. Karram;K. Choudhary.
Proceedings of the National Academy of Sciences of the United States of America (1997)

455 Citations

Chimeric brains generated by intraventricular transplantation of fetal human brain cells into embryonic rats

Oliver Brüstle;Oliver Brüstle;Oliver Brüstle;Khalid Choudhary;Khalid Choudhary;Khalad Karram;Khalad Karram;Khalad Karram;Anita Hüttner;Anita Hüttner.
Nature Biotechnology (1998)

409 Citations

Systemic administration of epothilone B promotes axon regeneration after spinal cord injury

Jörg Ruschel;Farida Hellal;Kevin C. Flynn;Sebastian Dupraz.
Science (2015)

367 Citations

Small molecules enable highly efficient neuronal conversion of human fibroblasts

Julia Ladewig;Jerome Mertens;Jaideep Kesavan;Jonas Doerr.
Nature Methods (2012)

342 Citations

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