2026 Adrienne W. Paton: Biology and Biochemistry Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Biology and Biochemistry	64	9554	8819	253	245	209	16833

Overview

Adrienne W. Paton is affiliated with the University of Adelaide in Australia, contributing extensively to the fields of Biochemistry, Genetics, and Molecular Biology, with additional work in Medicine. Their research is focused predominantly on Molecular Biology, Cell Biology, and Genetics, with notable exploration into Immunology and Surgery.

The scientist's work centers on several main topics, which include:

Endoplasmic Reticulum Stress and Disease
RNA regulation and disease
Glycosylation and Glycoproteins Research
Pancreatic function and diabetes
Monoclonal and Polyclonal Antibodies Research
Heat shock proteins research
Interferon and immune responses

Adrienne W. Paton has published in a variety of scientific venues, with frequent contributions to:

bioRxiv (Cold Spring Harbor Laboratory)
FEBS Journal
Nature Communications
Journal of Biological Chemistry
eLife

Notable recent papers authored or co-authored by Paton include:

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling, 2020, eLife
Factor VIII exhibits chaperone-dependent and glucose-regulated reversible amyloid formation in the endoplasmic reticulum, 2020, Blood
Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut, 2023, Immunity
IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress, 2020, The Journal of Cell Biology
All major cholesterol-dependent cytolysins use glycans as cellular receptors, 2020, Science Advances

The scientist frequently collaborates with several researchers, including:

James C. Paton
Andreia Mendes
Catarina R. Almeida
Philippe Pierre
Anita Pottekat

Best Publications

Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis.

Min Lu;David A. Lawrence;Scot Marsters;Diego Acosta-Alvear

631
Citations
Direct Detection and Characterization of Shiga Toxigenic Escherichia coli by Multiplex PCR for stx1, stx2, eae, ehxA, and saa

Adrienne W. Paton;James C. Paton

446
Citations
Characterization of Saa, a Novel Autoagglutinating Adhesin Produced by Locus of Enterocyte Effacement-Negative Shiga-Toxigenic Escherichia coli Strains That Are Virulent for Humans

Adrienne W. Paton;Potjanee Srimanote;Matthew C. Woodrow;James C. Paton

438
Citations
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP.

Adrienne W Paton;Travis Clarke Beddoe;Cheleste M Thorpe;James Whisstock

421
Citations
A New Family of Potent AB5 Cytotoxins Produced by Shiga Toxigenic Escherichia coli

Adrienne W. Paton;Potjanee Srimanote;Ursula M. Talbot;Hui Wang

371
Citations
Activation of the Akt-NF-κB Pathway by Subtilase Cytotoxin through the ATF6 Branch of the Unfolded Protein Response

Hiroaki Yamazaki;Nobuhiko Hiramatsu;Kunihiro Hayakawa;Yasuhiro Tagawa

314
Citations
Structure, Biological Functions and Applications of the AB5 Toxins

Travis Clarke Beddoe;Adrienne Webster Paton;Jerome Le Nours;Jamie Rossjohn

290
Citations
Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin.

Emma Byres;Adrienne W Paton;James C Paton;Jonas C Lofling

273
Citations
A new biological agent for treatment of Shiga toxigenic Escherichia coli infections and dysentery in humans

Adrienne W. Paton;Renato Morona;James C. Paton

255
Citations
ER Stress Causes Rapid Loss of Intestinal Epithelial Stemness through Activation of the Unfolded Protein Response

Jarom y Heijmans;Jooske F. van Lidth de Jeude;Bon-Kyoung Koo;Sanne L Rosekrans

253
Citations
IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation.

Shengyi Sun;Guojun Shi;Haibo Sha;Yewei Ji

210
Citations
BiP-mediated closing of the Sec61 channel limits Ca2+ leakage from the ER

Nico Schäuble;Sven Lang;Martin Jung;Sabine Cappel

186
Citations
Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways.

Jennifer J. Wolfson;Kerrie L. May;Cheleste M. Thorpe;Dakshina M. Jandhyala

170
Citations
Recombinant Probiotics for Treatment and Prevention of Enterotoxigenic Escherichia coli Diarrhea

Adrienne W. Paton;Michael P. Jennings;Renato Morona;Hui Wang

158
Citations
Shiga toxin-producing Escherichia coli strains negative for locus of enterocyte effacement.

Hayley J Newton;Joan Sloan;Dieter Mark Bulach;Torsten Seemann

134
Citations
LuxS Mediates Iron-Dependent Biofilm Formation, Competence, and Fratricide in Streptococcus pneumoniae

Claudia Trappetti;Adam J. Potter;Adrienne W. Paton;Marco R. Oggioni

134
Citations
Designer probiotics for prevention of enteric infections.

Adrienne W. Paton;Renato Morona;James C. Paton

133
Citations
The cholesterol-dependent cytolysins pneumolysin and streptolysin O require binding to red blood cell glycans for hemolytic activity.

Lucy K. Shewell;Richard M. Harvey;Melanie A. Higgins;Christopher J. Day

133
Citations
Multiplex PCR for direct detection of Shiga toxigenic Escherichia coli strains producing the novel subtilase cytotoxin.

Adrienne W. Paton;James C. Paton

128
Citations
A Recombinant Probiotic for Treatment and Prevention of Cholera

Antonio Focareta;James C. Paton;Renato Morona;Jan Cook

126
Citations