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D-Index & Metrics

Biology and Biochemistry

D-Index
47
Citations
7959
World Ranking
18715
National Ranking
7649

Overview

Yair Argon is affiliated with the Children's Hospital of Philadelphia in the United States. Their research contributions span several important topics and fields related to cellular and molecular biology, with a particular focus on stress responses within cells and associated diseases.

Their recent notable publications include:

  • mTORC1 coordinates an immediate unfolded protein response-related transcriptome in activated B cells preceding antibody secretion, 2020, Nature Communications
  • The special unfolded protein response in plasma cells, 2021, Immunological Reviews
  • Glucose-Regulated Protein 94 (GRP94): A Novel Regulator of Insulin-Like Growth Factor Production, 2020, Cells
  • Endoplasmic reticulum protein 5 attenuates platelet endoplasmic reticulum stress and secretion in a mouse model, 2022, Blood Advances
  • Glucose-Regulated Protein 94 (GRP94): A Novel Regulator of Insulin-Like Growth Factor Production, 2020, Preprints.org

Yair Argon's frequent co-authors include Lila M. Gierasch, F. Peter Guengerich, Ruma Banerjee, Roger Colbran, and Peter Cresswell. This indicates collaborative work across several research groups.

The scientist has published primarily in the following venues:

  • Journal of Biological Chemistry
  • The FASEB Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Immunological Reviews

Their work covers numerous subfields of study:

  • Cell Biology
  • Molecular Biology
  • Immunology
  • Surgery
  • Genetics

Main topics of their research encompass:

  • Endoplasmic Reticulum Stress and Disease
  • Pancreatic function and diabetes
  • Immune Cell Function and Interaction
  • Autophagy in Disease and Therapy
  • Growth Hormone and Insulin-like Growth Factors
  • Genetics and Neurodevelopmental Disorders
  • RNA regulation and disease

Best Publications

  • Sequential interaction of the chaperones BiP and GRP94 with immunoglobulin chains in the endoplasmic reticulum

    Jeffrey Melnick;Jeanne L. Dul;Yair Argon

  • GRP94: an HSP90-like protein specialized for protein folding and quality control in the Endoplasmic Reticulum

    Michal Marzec;Davide Eletto;Yair Argon

  • The endoplasmic reticulum stress protein GRP94, in addition to BiP, associates with unassembled immunoglobulin chains.

    J Melnick;S Aviel;Y Argon

  • GRP94, an ER chaperone with protein and peptide binding properties.

    Yair Argon;Birgitte B. Simen

  • Membrane biogenesis during B cell differentiation: most endoplasmic reticulum proteins are expressed coordinately.

    David L. Wiest;Janis K. Burkhardt;Susan Hester;Michael Hortsch

  • Sperm morphogenesis in wild-type and fertilization-defective mutants of Caenorhabditis elegans.

    S Ward;Y Argon;G A Nelson

  • Protein folding in the ER

    Fred J. Stevens;Yair Argon;Yair Argon

  • GRP94 in ER quality control and stress responses.

    Davide Eletto;Devin Dersh;Yair Argon

  • Protein Disulfide Isomerase A6 Controls the Decay of IRE1α Signaling via Disulfide-Dependent Association

    Davide Eletto;Daniela Eletto;Devin Dersh;Tali Gidalevitz

  • The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments.

    J K Burkhardt;S Hester;C K Lapham;Y Argon

  • Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants.

    Linda Hendershot;Jueyang Wei;James Gaut;Jeffrey Melnick

  • Interaction of Radicicol with Members of the Heat Shock Protein 90 Family of Molecular Chaperones

    Theodor W. Schulte;Shiro Akinaga;T. Murakata;Tsutomu Agatsuma

  • Redox controls UPR to control redox.

    Davide Eletto;Eric Chevet;Yair Argon;Christian Appenzeller-Herzog

  • GRP94 Is Essential for Mesoderm Induction and Muscle Development Because It Regulates Insulin-like Growth Factor Secretion

    Sherry Wanderling;Birgitte B. Simen;Olga Ostrovsky;Noreen T. Ahmed

  • Requirements for the Internalization of a Murine Monoclonal Antibody Directed against the HER-2/neu Gene Product c-erbB-2

    Lisa A. Maier;Feng Ji Xu;Susan Hester;Cinda M. Boyer

  • Orchestration of secretory protein folding by ER chaperones.

    Tali Gidalevitz;Fred Stevens;Yair Argon;Yair Argon

  • The giant organelles in beige and Chediak-Higashi fibroblasts are derived from late endosomes and mature lysosomes.

    J K Burkhardt;F A Wiebel;S Hester;Y Argon

  • Folding of Insulin Receptor Monomers Is Facilitated by the Molecular Chaperones Calnexin and Calreticulin and Impaired by Rapid Dimerization

    Joseph Bass;Gavin Chiu;Yair Argon;Donald F. Steiner

  • CAENORHABDITIS ELEGANS Fertilization-Defective Mutants with Abnormal Sperm

    Yair Argon;Samuel Ward

  • Development of a Grp94 inhibitor

    Adam S. Duerfeldt;Laura B. Peterson;Jason C. Maynard;Chun Leung Ng

Frequent Co-Authors

Janis K. Burkhardt
Janis K. Burkhardt University of Pennsylvania
Adrienne W. Paton
Adrienne W. Paton University of Adelaide
James C. Paton
James C. Paton University of Adelaide
Michael P. Sheetz
Michael P. Sheetz The University of Texas Medical Branch at Galveston
Robert C. Bast
Robert C. Bast The University of Texas MD Anderson Cancer Center
Gil Atzmon
Gil Atzmon Albert Einstein College of Medicine
Nemani V. Prasadarao
Nemani V. Prasadarao University of Southern California
Michael S. Marks
Michael S. Marks Children's Hospital of Philadelphia
Stephan A. Grupp
Stephan A. Grupp Children's Hospital of Philadelphia
David M. Barrett
David M. Barrett Children's Hospital of Philadelphia

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