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D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
13781
World Ranking
15981
National Ranking
388

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Ineke Braakman is affiliated with Utrecht University in the Netherlands. Their research portfolio spans multiple areas primarily within Medicine and Biochemistry, Genetics and Molecular Biology. They have contributed notably to the subfields of Pulmonary and Respiratory Medicine, Molecular Biology, Oncology, Infectious Diseases, and Genetics.

The scientist's work focuses on several key topics including Cystic Fibrosis Research Advances, Advanced Biosensing and Bioanalysis Techniques, Drug Transport and Resistance Mechanisms, Neonatal Respiratory Health Research, Bacterial Genetics and Biotechnology, HIV Research and Treatment, and Glycosylation and Glycoproteins Research.

Notable recent publications include:

  • The importance of naturally attenuated SARS-CoV -2 in the fight against COVID -19, 2020, Environmental Microbiology
  • Co-Translational Folding of the First Transmembrane Domain of ABC-Transporter CFTR is Supported by Assembly with the First Cytosolic Domain, 2021, Journal of Molecular Biology
  • The CFTR P67L variant reveals a key role for N-terminal lasso helices in channel folding, maturation, and pharmacologic rescue, 2021, Journal of Biological Chemistry
  • ABC-transporter CFTR folds with high fidelity through a modular, stepwise pathway, 2023, Cellular and Molecular Life Sciences
  • Intramolecular quality control: HIV-1 envelope gp160 signal-peptide cleavage as a functional folding checkpoint, 2021, Cell Reports

The publication venues where they have contributed multiple papers include bioRxiv (Cold Spring Harbor Laboratory), Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature, Journal of Molecular Biology, International Journal of Molecular Sciences, and The EMBO Journal.

Their frequent co-authors are:

  • Peter van der Sluijs
  • Tamara Hillenaar
  • Marcel van Willigen
  • Marjolein Mijnders
  • Bertrand Kleizen

Ineke Braakman was recognized as a Member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Role of N-linked oligosaccharide recognition, glucose trimming, and calnexin in glycoprotein folding and quality control.

    Craig Hammond;Ineke Braakman;Ari Helenius

  • Quality control in the endoplasmic reticulum protein factory.

    Roberto Sitia;Ineke Braakman

  • Protein Folding and Modification in the Mammalian Endoplasmic Reticulum

    Ineke Braakman;Neil J. Bulleid

  • Contribution of the endoplasmic reticulum to peroxisome formation.

    Dominic Hoepfner;Danny Schildknegt;Ineke Braakman;Peter Philippsen

  • Protein folding and quality control in the endoplasmic reticulum

    Bertrand Kleizen;Ineke Braakman

  • Protein Folding in the Endoplasmic Reticulum

    Ineke Braakman;Daniel N. Hebert

  • Manipulating disulfide bond formation and protein folding in the endoplasmic reticulum.

    I Braakman;J Helenius;A Helenius

  • Folding of influenza hemagglutinin in the endoplasmic reticulum.

    I Braakman;H Hoover-Litty;K R Wagner;A Helenius

  • Sequential Waves of Functionally Related Proteins Are Expressed When B Cells Prepare for Antibody Secretion

    Eelco van Anken;Edwin P Romijn;Claudia Maggioni;Alexandre Mezghrani

  • Role of ATP and disulphide bonds during protein folding in the endoplasmic reticulum.

    Ineke Braakman;Jonne Helenius;Ari Helenius

  • The endoplasmic reticulum as a protein-folding compartment.

    Ari Helenius;Thorsten Marquardt;Ineke Braakman

  • Manipulation of oxidative protein folding and PDI redox state in mammalian cells.

    Alexandre Mezghrani;Anna Fassio;Adam Benham;Thomas Simmen

  • Cotranslational folding and calnexin binding during glycoprotein synthesis.

    Wei Chen;Jonne Helenius;Ineke Braakman;Ari Helenius

  • Biochemically distinct vesicles from the endoplasmic reticulum fuse to form peroxisomes.

    Adabella van der Zand;Jürgen Gent;Ineke Braakman;Henk F. Tabak

  • Quality Control in the Secretory Pathway: The Role of Calreticulin, Calnexin and BiP in the Retention of Glycoproteins with C-Terminal Truncations

    Jian-Xin Zhang;Ineke Braakman;Kent E.S. Matlack;Ari Helenius

  • Coordinated nonvectorial folding in a newly synthesized multidomain protein.

    Annemieke Jansens;Esther van Duijn;Ineke Braakman

  • Peroxisomal membrane proteins insert into the endoplasmic reticulum.

    Adabella van der Zand;Ineke Braakman;Henk F. Tabak

  • Versatility of the endoplasmic reticulum protein folding factory.

    Eelco van Anken;Ineke Braakman

  • Folding of CFTR Is Predominantly Cotranslational

    Bertrand Kleizen;Thijs van Vlijmen;Hugo R. de Jonge;Ineke Braakman

  • Protein folding in the endoplasmic reticulum

    Ari Helenius;Utpal Tatu;Thorsten Marquardt;Ineke Braakman

Frequent Co-Authors

Ari Helenius
Ari Helenius ETH Zurich
Rogier W. Sanders
Rogier W. Sanders University of Amsterdam
Peter van der Sluijs
Peter van der Sluijs Utrecht University
Roberto Sitia
Roberto Sitia Vita-Salute San Raffaele University
Ben Berkhout
Ben Berkhout University of Amsterdam
Geny M. M. Groothuis
Geny M. M. Groothuis University of Groningen
Dirk K. F. Meijer
Dirk K. F. Meijer University of Groningen
Raymond A. Frizzell
Raymond A. Frizzell University of Pittsburgh
IngMarie Nilsson
IngMarie Nilsson Stockholm University
Gunnar von Heijne
Gunnar von Heijne Stockholm University

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