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Richard A. Rachubinski

Richard A. Rachubinski

D-Index & Metrics

Biology and Biochemistry

D-Index
73
Citations
16050
World Ranking
6046
National Ranking
214

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2002 - Fellow of the Royal Society of Canada Academy of Science

Overview

Richard A. Rachubinski is affiliated with the University of Alberta in Canada. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these areas, their work focuses extensively on Molecular Biology, Immunology, Genetics, Neurology, and Cell Biology.

The scientist's main topics of work include:

  • Peroxisome Proliferator-Activated Receptors
  • Immune Cell Function and Interaction
  • Immune cells in cancer
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Interferon and immune responses
  • Genomics and Rare Diseases
  • Genomic variations and chromosomal abnormalities

Their recent published papers demonstrate a focus on peroxisome biology and its role in immunity and disease. Notable recent publications include:

  • "The peroxisome: an up-and-coming organelle in immunometabolism," 2022, published in Trends in Cell Biology
  • "The Canadian Rare Diseases Models and Mechanisms (RDMM) Network: Connecting Understudied Genes to Model Organisms," 2020, published in The American Journal of Human Genetics
  • "Peroxisomes exhibit compromised structure and matrix protein content in SARS-CoV-2-infected cells," 2021, published in Molecular Biology of the Cell
  • "Peroxisome prognostications: Exploring the birth, life, and death of an organelle," 2020, published in The Journal of Cell Biology
  • "Peroxisome Injury in Multiple Sclerosis: Protective Effects of 4-Phenylbutyrate in CNS-Associated Macrophages," 2022, published in Journal of Neuroscience

Richard A. Rachubinski's frequent co-authors include Francesca Di Cara, Gary Eitzen, Andrej Roczkowsky, Christopher Power, and Barbara Knoblach.

They have published work repeatedly in the following venues:

  • The Journal of Cell Biology
  • Frontiers in Cell and Developmental Biology
  • Trends in Cell Biology
  • The American Journal of Human Genetics
  • Journal of Neuroscience

Throughout their career, Rachubinski has received recognition including the Fellow of the Royal Society of Canada in 2002, cited by the Academy of Science, and the Fellow of the American Association for the Advancement of Science (AAAS) in 2014.

Best Publications

  • A novel, cleavable peroxisomal targeting signal at the amino-terminus of the rat 3-ketoacyl-coA thiolase

    B.W. Swinkels;S.J. Gould;A.G. Bodnar;R.A. Rachubinski

  • Cargo-selected transport from the mitochondria to peroxisomes is mediated by vesicular carriers.

    Margaret Neuspiel;Astrid C. Schauss;Emelie Braschi;Rodolfo Zunino

  • A unified nomenclature for peroxisome biogenesis factors.

    B. Distel;R. Erdmann;S. J. Gould;G. Blobel

  • Saccharomyces cerevisiae peroxisomal thiolase is imported as a dimer

    John R. Glover;David W. Andrews;Richard A. Rachubinski

  • Molecular cloning and expression of the major protein kinase C substrate of platelets

    Michael Tyers;Richard A. Rachubinski;Mary I. Stewart;Angela M. Varrichio

  • Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase.

    Baowei Zhang;Sandra L. Marcus;Fereydoun G. Sajjadi;Keith Alvares

  • How proteins penetrate peroxisomes

    Richard A. Rachubinski;Suresh Subramani

  • Synthesis of a major integral membrane polypeptide of rat liver peroxisomes on free polysomes

    Yukio Fujiki;Richard A. Rachubinski;Paul B. Lazarow

  • Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive elements of the rat hydratase/dehydrogenase and fatty acyl-CoA oxidase genes but differentially induce expression

    Sandra L. Marcus;Kenji S. Miyata;Baowei Zhang;Suresh Subramani

  • The life cycle of the peroxisome

    Vladimir I. Titorenko;Richard A. Rachubinski

  • Transcriptome profiling to identify genes involved in peroxisome assembly and function

    Jennifer J. Smith;Marcello Marelli;Rowan H. Christmas;Franco J. Vizeacoumar

  • Mutants of the yeast Yarrowia lipolytica defective in protein exit from the endoplasmic reticulum are also defective in peroxisome biogenesis.

    Vladimir I. Titorenko;Richard A. Rachubinski

  • Pex3p Initiates the Formation of a Preperoxisomal Compartment from a Subdomain of the Endoplasmic Reticulum in Saccharomyces cerevisiae

    Yuen Yi C. Tam;Andrei Fagarasanu;Monica Fagarasanu;Richard A. Rachubinski

  • Mutagenesis of the amino targeting signal of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase reveals conserved amino acids required for import into peroxisomes in vivo.

    J.R. Glover;D.W. Andrews;S. Subramani;R.A. Rachubinski

  • Lack of Peroxisomal Catalase Causes a Progeric Phenotype in Caenorhabditis elegans

    Oleh I. Petriv;Richard A. Rachubinski

  • Quantitative mass spectrometry reveals a role for the GTPase Rho1p in actin organization on the peroxisome membrane

    Marcello Marelli;Jennifer J. Smith;Sunhee Jung;Eugene Yi

  • Enlarged Peroxisomes Are Present in Oleic Acid–grown Yarrowia lipolytica Overexpressing the PEX16 Gene Encoding an Intraperoxisomal Peripheral Membrane Peroxin

    Gary A. Eitzen;Rachel K. Szilard;Richard A. Rachubinski

  • Fusion of Small Peroxisomal Vesicles in Vitro Reconstructs an Early Step in the in Vivo Multistep Peroxisome Assembly Pathway of Yarrowia lipolytica

    Vladimir I. Titorenko;Honey Chan;Richard A. Rachubinski

  • Involvement of 70-kD heat-shock proteins in peroxisomal import.

    P. A. Walton;M. Wendland;Suresh Subramani;R. A. Rachubinski

  • Pex20p of the Yeast Yarrowia lipolytica Is Required for the Oligomerization of Thiolase in the Cytosol and for Its Targeting to the Peroxisome

    Vladimir I. Titorenko;Jennifer J. Smith;Rachel K. Szilard;Richard A. Rachubinski

Frequent Co-Authors

John D. Aitchison
John D. Aitchison University of Minnesota
Vladimir I. Titorenko
Vladimir I. Titorenko Concordia University
Suresh Subramani
Suresh Subramani University of California, San Diego
Morris A. Blajchman
Morris A. Blajchman McMaster University
John J. M. Bergeron
John J. M. Bergeron McGill University
Joel B. Dacks
Joel B. Dacks University of Alberta
David W. Andrews
David W. Andrews Sunnybrook Health Science Centre
Richard C. Austin
Richard C. Austin McMaster University
Barry I. Posner
Barry I. Posner McGill University
Calvin B. Harley
Calvin B. Harley Geron (United States)

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