Calvin B. Harley

Overview

Best Publications

• Specific association of human telomerase activity with immortal cells and cancer

  Nam W. Kim;Mieczyslaw A. Piatyszek;Karen R. Prowse;Calvin B. Harley

  10238
  Citations

• Telomeres shorten during ageing of human fibroblasts.

  C B Harley;A B Futcher;C W Greider

  7342
  Citations

• EXTENSION OF LIFE-SPAN BY INTRODUCTION OF TELOMERASE INTO NORMAL HUMAN CELLS

  Andrea G. Bodnar;Michel Ouellette;Maria Frolkis;Shawn E. Holt

  6652
  Citations

• The RNA component of human telomerase

  Junli Feng;Walter D. Funk;Sy Shi Wang;Scott L. Weinrich

  3423
  Citations

• Telomerase catalytic subunit homologs from fission yeast and human

  Toru M. Nakamura;Gregg B. Morin;Gregg B. Morin;Karen B. Chapman;Karen B. Chapman;Scott L. Weinrich;Scott L. Weinrich

  3121
  Citations

• Telomere length predicts replicative capacity of human fibroblasts.

  R C Allsopp;H Vaziri;C Patterson;S Goldstein

  2938
  Citations

• Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

  C.M. Counter;A.A. Avilion;C.E. LeFeuvre;N.G. Stewart

  2858
  Citations

• Telomere loss: mitotic clock or genetic time bomb?

  Calvin B. Harley

  1675
  Citations

• Analysis of E. coli promoter sequences.

  Calvin B. Harley;Robert P. Reynolds

  1494
  Citations

• Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age

  Homayoun Vaziri;Wieslawa Dragowska;Richard C. Allsopp;Terry E. Thomas

  1459
  Citations

• Telomere end-replication problem and cell aging.

  Michael Z. Levy;Richard C. Allsopp;A.Bruce Futcher;Carol W. Greider

  1423
  Citations

• Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

  Scott L. Weinrich;Ron Pruzan;Libin Ma;Michel Ouellette

  1325
  Citations

• Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes

  H. Vaziri;F. Schächter;I. Uchida;Lan Wei

  1102
  Citations

• Telomerase activity in normal leukocytes and in hematologic malignancies.

  Christopher M. Counter;Jyothi Gupta;Calvin B. Harley;Brian Leber

  1090
  Citations

• Telomerase activity in human ovarian carcinoma.

  Christopher M. Counter;Hal W. Hirte;Silvia Bacchetti;Calvin B. Harley

  1042
  Citations

• Telomerase and cancer therapeutics

  Calvin B. Harley

  973
  Citations

• Telomere length and replicative aging in human vascular tissues

  Edwin Chang;Calvin B. Harley

  900
  Citations

• Telomere Shortening Is Associated with Cell Division in Vitro and in Vivo

  Richard C. Allsopp;Edwin Chang;Mohammad Kashefi-Aazam;Evgeny I. Rogaev

  715
  Citations

• The telomere hypothesis of cellular aging.

  Calvin B. Harley;Homayoun Vaziri;Christopher M. Counter;Richard C. Allsopp

  685
  Citations

• Evidence for a Critical Telomere Length in Senescent Human Fibroblasts

  Richard C. Allsopp;Calvin B. Harley

  550
  Citations