What is she best known for?
The fields of study she is best known for:
Her primary areas of study are Cell biology, Telomere, Senescence, DNA damage and Genetics.
Her Cell biology study focuses on Mitochondrion in particular.
Her biological study deals with issues like Mitochondrial DNA, which deal with fields such as Mitochondrial ROS and Telomerase.
The Senescence study combines topics in areas such as NFKB1, Molecular biology, Ageing and Liver regeneration.
The various areas that Gabriele Saretzki examines in her Molecular biology study include Fibroblast, Cell cycle checkpoint, Checkpoint Kinase 2 and Gene product.
Her DNA damage study which covers DNA repair that intersects with Stem cell, Cellular differentiation, MDC1, CHEK1 and G2-M DNA damage checkpoint.
Her most cited work include:
- A DNA damage checkpoint response in telomere-initiated senescence (2025 citations)
- Mild Hyperoxia Shortens Telomeres and Inhibits Proliferation of Fibroblasts: A Model for Senescence? (736 citations)
- Feedback between p21 and reactive oxygen production is necessary for cell senescence (522 citations)
What are the main themes of her work throughout her whole career to date?
The scientist’s investigation covers issues in Telomere, Cell biology, Telomerase, Senescence and Telomerase reverse transcriptase.
In her study, Cancer is inextricably linked to Apoptosis, which falls within the broad field of Telomere.
Her Cell biology research integrates issues from Oxidative stress, Embryonic stem cell, DNA damage and Genetics.
Her DNA damage research is multidisciplinary, relying on both Stem cell and DNA repair.
Gabriele Saretzki combines subjects such as Cell culture, Cancer research, Immunology, Molecular biology and Endometrium with her study of Telomerase.
A large part of her Senescence studies is devoted to Cell aging.
She most often published in these fields:
- Telomere (55.07%)
- Cell biology (54.35%)
- Telomerase (45.65%)
What were the highlights of her more recent work (between 2015-2021)?
- Telomerase (45.65%)
- Telomere (55.07%)
- Cell biology (54.35%)
In recent papers she was focusing on the following fields of study:
Gabriele Saretzki spends much of her time researching Telomerase, Telomere, Cell biology, Cancer research and Telomerase reverse transcriptase.
Her Telomerase research incorporates themes from Endometrium, Cancer cell and Endometrial cancer.
Her Telomere study combines topics in areas such as Autophagy, Oxidative stress, Ex vivo, In vitro and Cell cycle checkpoint.
Her Cell biology study incorporates themes from Cellular differentiation, DNA damage and Induced pluripotent stem cell.
She interconnects Argan oil, Pharmacology and DNA repair in the investigation of issues within DNA damage.
Her Telomerase reverse transcriptase research is multidisciplinary, incorporating perspectives in Stem cell, Neural stem cell, Immunology and Human brain.
Between 2015 and 2021, her most popular works were:
- Mitochondria are required for pro‐ageing features of the senescent phenotype (271 citations)
- The bystander effect contributes to the accumulation of senescent cells in vivo. (49 citations)
- Decreased mTOR signalling reduces mitochondrial ROS in brain via accumulation of the telomerase protein TERT within mitochondria (39 citations)
In her most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Cell biology, Telomerase, Immunology, Telomere and Induced pluripotent stem cell.
Her Cell biology research is multidisciplinary, incorporating elements of Sarcopenia and Skeletal muscle.
Telomerase reverse transcriptase is the focus of her Telomerase research.
Her research integrates issues of Cellular differentiation, Gene expression profiling, Reprogramming and Transforming growth factor beta, Signal transduction in her study of Immunology.
Her Telomere study frequently draws connections to other fields, such as DNA damage.
Her work deals with themes such as Phenotype, mTORC1, In vivo and Mitochondrial biogenesis, which intersect with Senescence.
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