D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Molecular Biology D-index 56 Citations 23,065 112 World Ranking 1493 National Ranking 46

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • DNA
  • Cancer

Telomerase, Telomerase reverse transcriptase, Molecular biology, Telomere and Telomerase RNA component are her primary areas of study. Her work deals with themes such as Cell, Cell aging, Cancer research and DNA replication, which intersect with Telomerase. Her Telomerase reverse transcriptase research includes elements of Carcinogenesis and Cell biology.

Her biological study spans a wide range of topics, including Cell culture and Regulation of gene expression, Gene, Cellular differentiation. Her Telomere research includes themes of Chromosome and Cell division. Her work in Telomerase RNA component addresses subjects such as Ribonucleoprotein, which are connected to disciplines such as Tumor progression.

Her most cited work include:

  • A survey of telomerase activity in human cancer (2344 citations)
  • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. (1902 citations)
  • hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization (1721 citations)

What are the main themes of her work throughout her whole career to date?

Her scientific interests lie mostly in Molecular biology, Telomerase, Telomere, Telomerase reverse transcriptase and Cell culture. Her Molecular biology study integrates concerns from other disciplines, such as Virus, Herpes simplex virus and Biochemistry, Gene, DNA. The study incorporates disciplines such as Cancer research, Carcinogenesis, RNA, Cell aging and Cell biology in addition to Telomerase.

Her research in Telomere intersects with topics in Chromosome, Cell division, Senescence and Somatic cell. In general Telomerase reverse transcriptase study, her work on Telomerase RNA component often relates to the realm of Telomere-binding protein, thereby connecting several areas of interest. Her Cell culture research incorporates elements of Gene expression and Mutant.

She most often published in these fields:

  • Molecular biology (51.28%)
  • Telomerase (32.48%)
  • Telomere (25.64%)

What were the highlights of her more recent work (between 2003-2015)?

  • Telomerase (32.48%)
  • Cell biology (17.09%)
  • Cancer research (14.53%)

In recent papers she was focusing on the following fields of study:

Her primary areas of investigation include Telomerase, Cell biology, Cancer research, Enos and Telomere. Her research in Telomerase is mostly concerned with Telomerase reverse transcriptase. Silvia Bacchetti is studying Telomerase RNA component, which is a component of Telomerase reverse transcriptase.

The concepts of her Cell biology study are interwoven with issues in Cell cycle, Immunology, Bioluminescence imaging and Endothelial cell differentiation. Her Cancer research study combines topics in areas such as Transcriptional regulation, Chromatin remodeling, Prostate cancer and Gene expression profiling. Her Telomere research is multidisciplinary, incorporating perspectives in Molecular biology, Chromosome, Chromosome instability and Cell division.

Between 2003 and 2015, her most popular works were:

  • Alternative Lengthening of Telomeres Is Characterized by High Rates of Telomeric Exchange (241 citations)
  • Multi-centre phase II clinical trial of yttrium-90 resin microspheres alone in unresectable, chemotherapy refractory colorectal liver metastases. (169 citations)
  • Probing PML body function in ALT cells reveals spatiotemporal requirements for telomere recombination (102 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Cancer

Silvia Bacchetti focuses on Telomere, Telomerase, Chromosome, Prostate cancer and Cancer research. Her Telomere research incorporates elements of Molecular biology, Chromosome instability, Molecular evolution and Cell division. Her Molecular biology study combines topics from a wide range of disciplines, such as Metaphase, Nuclear protein, Recombination and Cell biology.

Her Telomerase research incorporates themes from Chromosome Arm and Karyotype. Her Prostate cancer research includes elements of Phenotype, Prostate, Cellular differentiation and Gene expression profiling. Her research in Cancer research tackles topics such as Chromatin remodeling which are related to areas like Cancer and Internal medicine.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A survey of telomerase activity in human cancer

Jerry W Shay;S. Bacchetti.
European Journal of Cancer (1997)

3731 Citations

Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.

C.M. Counter;A.A. Avilion;C.E. LeFeuvre;N.G. Stewart.
The EMBO Journal (1992)

2801 Citations

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization

Matthew Meyerson;Christopher M Counter;Elinor Ng Eaton;Leif W Ellisen.
Cell (1997)

2539 Citations

Telomere elongation in immortal human cells without detectable telomerase activity.

Tracy M. Bryan;Anna Englezou;Jyothi Gupta;Silvia Bacchetti.
The EMBO Journal (1995)

1692 Citations

Telomerase activity in normal leukocytes and in hematologic malignancies.

Christopher M. Counter;Jyothi Gupta;Calvin B. Harley;Brian Leber.
Blood (1995)

1075 Citations

Telomerase activity in human ovarian carcinoma.

Christopher M. Counter;Hal W. Hirte;Silvia Bacchetti;Calvin B. Harley.
Proceedings of the National Academy of Sciences of the United States of America (1994)

1034 Citations

The Human Telomerase Catalytic Subunit hTERT: Organization of the Gene and Characterization of the Promoter

Yu-Sheng Cong;Jianping Wen;Silvia Bacchetti.
Human Molecular Genetics (1999)

694 Citations

Human telomerase RNA and telomerase activity in immortal cell lines and tumor tissues

Ariel A. Avilion;Mieczyslaw A. Piatyszek;Jyothi Gupta;Jerry W. Shay.
Cancer Research (1996)

674 Citations

Telomerase, Cell Immortality, and Cancer

C. B. Harley;N. W. Kim;K. R. Prowse;S. L. Weinrich.
Cold Spring Harbor Symposia on Quantitative Biology (1994)

527 Citations

Telomerase activity associated with acquisition of malignancy in human colorectal cancer.

Corinne Chadeneau;Kazy Hay;Hal W. Hirte;Steven Gallinger.
Cancer Research (1995)

486 Citations

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