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Molecular Biology

D-Index
50
Citations
30648
World Ranking
2522
National Ranking
79

Overview

Gregg B. Morin is affiliated with the University of British Columbia in Canada, contributing extensively to research in biochemistry, genetics, molecular biology, and medicine. Their scholarly work predominantly focuses on molecular biology, oncology, immunology, spectroscopy, and pulmonary and respiratory medicine.

The scientist's research topics cover a range of specialized areas including RNA modifications and cancer, advanced proteomics techniques and applications, cancer genomics and diagnostics, ovarian cancer diagnosis and treatment, acute myeloid leukemia research, mass spectrometry techniques and applications, and chromatin remodeling and cancer.

The following are some of their recent papers, illustrating the scope of their research:

  • Proteomic analysis of archival breast cancer clinical specimens identifies biological subtypes with distinct survival outcomes, 2022, Nature Communications
  • Proteomic Screens for Suppressors of Anoikis Identify IL1RAP as a Promising Surface Target in Ewing Sarcoma, 2021, Cancer Discovery
  • Loss of m1acp3Ψ Ribosomal RNA Modification Is a Major Feature of Cancer, 2020, Cell Reports
  • Chloroquine treatment induces secretion of autophagy-related proteins and inclusion of Atg8-family proteins in distinct extracellular vesicle populations, 2022, Autophagy
  • Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism, 2020, eLife

Gregg B. Morin has collaborated frequently with a number of researchers, indicating active scientific partnership and cross-disciplinary work. Frequent co-authors include:

  • Gian Luca Negri
  • Sandra E. Spencer Miko
  • Shane Colborne
  • David G. Huntsman
  • Poul H. Sorensen

The scientist's work appears in several prominent publication venues with notable frequency, reflecting the dissemination channels favored for their research:

  • Cancer Research (14 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (11 publications)
  • Nature Communications (9 publications)
  • Clinical Cancer Research (7 publications)
  • Journal of Proteome Research (4 publications)

Best Publications

  • EXTENSION OF LIFE-SPAN BY INTRODUCTION OF TELOMERASE INTO NORMAL HUMAN CELLS

    Andrea G. Bodnar;Michel Ouellette;Maria Frolkis;Shawn E. Holt

  • Telomerase catalytic subunit homologs from fission yeast and human

    Toru M. Nakamura;Gregg B. Morin;Gregg B. Morin;Karen B. Chapman;Karen B. Chapman;Scott L. Weinrich;Scott L. Weinrich

  • The clonal and mutational evolution spectrum of primary triple-negative breast cancers

    Sohrab P. Shah;Andrew Roth;Rodrigo Goya;Arusha Oloumi

  • The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

    Gregg B. Morin

  • ARID1A mutations in endometriosis-associated ovarian carcinomas.

    Kimberly C. Wiegand;Sohrab P. Shah;Osama M. Al-Agha;Yongjun Zhao

  • Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT

    Scott L. Weinrich;Ron Pruzan;Libin Ma;Michel Ouellette

  • Single-pot, solid-phase-enhanced sample preparation for proteomics experiments.

    Christopher S. Hughes;Sophie Moggridge;Sophie Moggridge;Torsten Müller;Poul H. Sorensen

  • Large‐scale mapping of human protein–protein interactions by mass spectrometry

    Rob M. Ewing;Peter Chu;Fred Elisma;Hongyan Li

  • Functional requirement of p23 and Hsp90 in telomerase complexes

    Shawn E. Holt;Shawn E. Holt;Dara L. Aisner;Joseph Baur;Valerie M. Tesmer

  • Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation.

    Damian B. Yap;Damian B. Yap;Justin Chu;Tobias Berg;Matthieu Schapira

  • Telomerase reverse transcriptase gene is a direct target of c-Myc but is not functionally equivalent in cellular transformation

    Roger A. Greenberg;Rónán C. O'Hagan;Hongyu Deng;Qiurong Xiao

  • Recurrent Somatic DICER1 Mutations in Nonepithelial Ovarian Cancers

    Alireza Heravi-Moussavi;Michael S Anglesio;S-W Grace Cheng;Janine Senz

  • Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation.

    Roger A. Greenberg;Richard C. Allsopp;Richard C. Allsopp;Lynda Chin;Gregg B. Morin

  • Alternative expression analysis by RNA sequencing.

    Malachi Griffith;Malachi Griffith;Obi L Griffith;Obi L Griffith;Jill Mwenifumbo;Rodrigo Goya

  • Telomerase is required to slow telomere shortening and extend replicative lifespan of HSCs during serial transplantation

    Richard C. Allsopp;Gregg B. Morin;Gregg B. Morin;Gregg B. Morin;Ronald DePinho;Calvin B. Harley;Calvin B. Harley;Calvin B. Harley

  • Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers.

    Stephen Yip;Yaron S. Butterfield;Olena Morozova;Suganthi Chittaranjan

  • TANK2, a New TRF1-associated Poly(ADP-ribose) Polymerase, Causes Rapid Induction of Cell Death upon Overexpression

    Patrick G. Kaminker;Sahn Ho Kim;Rebecca D. Taylor;Yeganeh Zebarjadian

  • Recognition of a chromosome truncation site associated with α-thalassaemia by human telomerase

    G.B. Morin

  • Extending the Compatibility of the SP3 Paramagnetic Bead Processing Approach for Proteomics

    Sophie Moggridge;Sophie Moggridge;Poul H. Sorensen;Gregg B. Morin;Gregg B. Morin;Christopher S. Hughes

  • Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage.

    M S Anglesio;Y Wang;W Yang;J Senz

Frequent Co-Authors

Thomas R. Cech
Thomas R. Cech University of Colorado Boulder
Joachim Lingner
Joachim Lingner École Polytechnique Fédérale de Lausanne
Calvin B. Harley
Calvin B. Harley Geron (United States)
David G. Huntsman
David G. Huntsman University of British Columbia
Marco A. Marra
Marco A. Marra University of British Columbia
Martin Hirst
Martin Hirst University of British Columbia
Ryan D. Morin
Ryan D. Morin Simon Fraser University
Samuel Aparicio
Samuel Aparicio University of British Columbia
Poul H. Sorensen
Poul H. Sorensen University of British Columbia
Steven J.M. Jones
Steven J.M. Jones University of British Columbia

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