World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
85
Citations
43917
World Ranking
1280
National Ranking
608

Medicine

D-Index
85
Citations
43943
World Ranking
14369
National Ranking
7264

Overview

Sohrab P. Shah is affiliated with Memorial Sloan Kettering Cancer Center in the United States. Their research spans multiple disciplines, primarily within biochemistry, genetics, molecular biology, and medicine, with a strong focus on cancer-related studies.

The scientist's main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Significant subfields of study in their work cover:

  • Molecular Biology
  • Cancer Research
  • Oncology
  • Pulmonary and Respiratory Medicine
  • Immunology

Their research topics address a range of areas in cancer biology and diagnostics, including:

  • Cancer Genomics and Diagnostics
  • Single-cell and spatial transcriptomics
  • Radiomics and Machine Learning in Medical Imaging
  • Epigenetics and DNA Methylation
  • Ovarian cancer diagnosis and treatment
  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction

Among recent papers associated with their scope of work are:

  • Eleven grand challenges in single-cell data science (2020, Genome Biology)
  • Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients (2022, Cell)
  • Harnessing multimodal data integration to advance precision oncology (2021, Nature Reviews. Cancer)
  • ESMO recommendations on predictive biomarker testing for homologous recombination deficiency and PARP inhibitor benefit in ovarian cancer (2020, Annals of Oncology)
  • Imaging mass cytometry and multiplatform genomics define the phenogenomic landscape of breast cancer (2020, Nature Cancer)

Frequent co-authors collaborating with Sohrab P. Shah include:

  • Andrew McPherson
  • Nicholas Ceglia
  • Samuel Aparício
  • Marc Williams
  • Ignacio Vázquez-Garćıa

Common publication venues for their work encompass:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature
  • Clinical Cancer Research

Best Publications

  • The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

    Christina Curtis;Christina Curtis;Sohrab P Shah;Suet-Feung Chin;Gulisa Turashvili

  • The clonal and mutational evolution spectrum of primary triple-negative breast cancers

    Sohrab P. Shah;Andrew Roth;Rodrigo Goya;Arusha Oloumi

  • Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

    Morin Rd;Johnson Na;Severson Tm;Mungall Aj

  • ARID1A mutations in endometriosis-associated ovarian carcinomas.

    Kimberly C. Wiegand;Sohrab P. Shah;Osama M. Al-Agha;Yongjun Zhao

  • The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes

    Bernard Pereira;Suet Feung Chin;Oscar M. Rueda;Hans Kristian Moen Vollan

  • Tumor-Associated Macrophages and Survival in Classic Hodgkin's Lymphoma

    Christian Steidl;Tang Lee;Sohrab P. Shah;Pedro Farinha

  • Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

    Sohrab P. Shah;Ryan D. Morin;Jaswinder Khattra;Leah Prentice

  • Eleven grand challenges in single-cell data science

    David Lähnemann;David Lähnemann;Johannes Köster;Johannes Köster;Ewa Szczurek;Davis J. McCarthy;Davis J. McCarthy

  • PyClone: statistical inference of clonal population structure in cancer

    Andrew Roth;Jaswinder Khattra;Damian Yap;Adrian Wan

  • Mutation of FOXL2 in Granulosa-Cell Tumors of the Ovary

    Sohrab P Shah;Martin Köbel;Janine Senz;Ryan D Morin

  • Hereditary diffuse gastric cancer syndrome: CDH1 mutations and beyond

    Samantha Hansford;Pardeep Kaurah;Hector Li-Chang;Michelle Woo

  • Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution

    Peter Eirew;Peter Eirew;Adi Steif;Adi Steif;Jaswinder Khattra;Jaswinder Khattra;Gavin Ha;Gavin Ha

  • MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers

    Christian Steidl;Sohrab P. Shah;Bruce W. Woolcock;Lixin Rui

  • Defuse: An algorithm for gene fusion discovery in tumor rna-seq data

    Andrew McPherson;Fereydoun Hormozdiari;Abdalnasser Zayed;Ryan Giuliany

  • Spatial genomic heterogeneity within localized, multifocal prostate cancer

    Paul C. Boutros;Paul C. Boutros;Michael Fraser;Nicholas J. Harding;Richard De Borja

  • Recurrent Somatic DICER1 Mutations in Nonepithelial Ovarian Cancers

    Alireza Heravi-Moussavi;Michael S Anglesio;S-W Grace Cheng;Janine Senz

  • Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer

    Muhammed Murtaza;Sarah-Jane Dawson;Sarah-Jane Dawson;Sarah-Jane Dawson;Katherine Pogrebniak;Oscar M. Rueda

  • CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.

    Hong Xu;Marco Di Antonio;Steven McKinney;Veena Mathew

  • Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling

    Ali Bashashati;Gavin Ha;Alicia Tone;Jiarui Ding;Jiarui Ding

  • Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing.

    Ryan D. Morin;Ryan D. Morin;Karen Mungall;Erin Pleasance;Andrew J. Mungall

Frequent Co-Authors

Samuel Aparicio
Samuel Aparicio University of British Columbia
David G. Huntsman
David G. Huntsman University of British Columbia
Marco A. Marra
Marco A. Marra University of British Columbia
Christian Steidl
Christian Steidl University of British Columbia
Randy D. Gascoyne
Randy D. Gascoyne BC Cancer Agency
Ryan D. Morin
Ryan D. Morin Simon Fraser University
Joseph M. Connors
Joseph M. Connors University of British Columbia
Gavin Ha
Gavin Ha Fred Hutchinson Cancer Research Center
Martin Hirst
Martin Hirst University of British Columbia
Andrew J. Mungall
Andrew J. Mungall BC Cancer Agency

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