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Biology and Biochemistry

D-Index
61
Citations
48206
World Ranking
11071
National Ranking
4784

Overview

Gavin Ha is affiliated with the Fred Hutchinson Cancer Research Center in the United States. Their research contributions span multiple areas within biochemistry, genetics, molecular biology, and medicine, with particular emphasis on cancer genomics and diagnostics.

The main fields of study in which Gavin Ha is active include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader areas, their work focuses on several subfields:

  • Molecular Biology
  • Cancer Research
  • Pulmonary and Respiratory Medicine
  • Oncology
  • Pathology and Forensic Medicine

Their research topics include:

  • Cancer Genomics and Diagnostics
  • Prostate Cancer Treatment and Research
  • Genetic factors in colorectal cancer
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Molecular Biology Techniques and Applications
  • Lung Cancer Treatments and Mutations

Gavin Ha has contributed to several scientific publications, with recent papers including:

  • The evolutionary history of 2,658 cancers, 2020, Nature
  • Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes, 2021, Cell
  • Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring, 2020, Nature Medicine
  • Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress, 2020, Cell Reports
  • Prostate cancer reactivates developmental epigenomic programs during metastatic progression, 2020, Nature Genetics

Frequent co-authors collaborating with Gavin Ha include:

  • Peter S. Nelson
  • Bruce Montgomery
  • Viktor A. Adalsteinsson
  • Minjeong Ko
  • Gad Getz

Gavin Ha's work has been published in journals and venues where they have maintained frequent contributions, such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cancer Research
  • Nature Communications
  • Clinical Cancer Research
  • npj Precision Oncology

Best Publications

  • The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

    Christina Curtis;Christina Curtis;Sohrab P Shah;Suet-Feung Chin;Gulisa Turashvili

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Oncogenic Signaling Pathways in The Cancer Genome Atlas

    Francisco Sanchez-Vega;Marco Mina;Joshua Armenia;Walid K. Chatila

  • Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer.

    Katherine A. Hoadley;Christina Yau;Christina Yau;Toshinori Hinoue;Denise M. Wolf

  • Comprehensive Characterization of Cancer Driver Genes and Mutations.

    Matthew H Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

  • The clonal and mutational evolution spectrum of primary triple-negative breast cancers

    Sohrab P. Shah;Andrew Roth;Rodrigo Goya;Arusha Oloumi

  • ARID1A mutations in endometriosis-associated ovarian carcinomas.

    Kimberly C. Wiegand;Sohrab P. Shah;Osama M. Al-Agha;Yongjun Zhao

  • Genomic and Functional Approaches to Understanding Cancer Aneuploidy

    Alison M. Taylor;Alison M. Taylor;Juliann Shih;Gavin Ha;Gavin Ha;Galen F. Gao

  • The evolutionary history of 2,658 cancers

    Moritz Gerstung;Moritz Gerstung;Clemency Jolly;Ignaty Leshchiner;Stefan C Dentro;Stefan C Dentro;Stefan C Dentro

  • PyClone: statistical inference of clonal population structure in cancer

    Andrew Roth;Jaswinder Khattra;Damian Yap;Adrian Wan

  • Patterns of somatic structural variation in human cancer genomes

    Yilong Li;Nicola D Roberts;Jeremiah A Wala;Jeremiah A Wala;Ofer Shapira;Ofer Shapira

  • Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.

    André Kahles;Kjong-Van Lehmann;Nora C Toussaint;Matthias Hüser

  • Pathogenic Germline Variants in 10,389 Adult Cancers

    Kuan-Lin Huang;R Jay Mashl;Yige Wu;Deborah I Ritter

  • Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors

    Viktor A. Adalsteinsson;Viktor A. Adalsteinsson;Gavin Ha;Gavin Ha;Samuel S. Freeman;Samuel S. Freeman;Atish D. Choudhury

  • Genetic and transcriptional evolution alters cancer cell line drug response

    Uri Ben-David;Benjamin Siranosian;Gavin Ha;Gavin Ha;Helen Tang

  • Patient-derived xenografts undergo mouse-specific tumor evolution.

    Uri Ben-David;Gavin Ha;Gavin Ha;Yuen-Yi Tseng;Noah F Greenwald;Noah F Greenwald;Noah F Greenwald

  • Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution

    Peter Eirew;Peter Eirew;Adi Steif;Adi Steif;Jaswinder Khattra;Jaswinder Khattra;Gavin Ha;Gavin Ha

  • Genomic Copy Number Dictates a Gene-Independent Cell Response to CRISPR/Cas9 Targeting

    Andrew J Aguirre;Robin M Meyers;Barbara A. Weir;Francisca Vázquez

  • Defuse: An algorithm for gene fusion discovery in tumor rna-seq data

    Andrew McPherson;Fereydoun Hormozdiari;Abdalnasser Zayed;Ryan Giuliany

  • Erratum: Comprehensive Characterization of Cancer Driver Genes and Mutations (ARTICLE (2018) 173(2) (371–385), (S009286741830237X), (10.1016/j.cell.2018.02.060))

    Matthew H. Bailey;Collin Tokheim;Eduard Porta-Pardo;Sohini Sengupta

Frequent Co-Authors

Matthew Meyerson
Matthew Meyerson Harvard University
Sohrab P. Shah
Sohrab P. Shah Memorial Sloan Kettering Cancer Center
David G. Huntsman
David G. Huntsman University of British Columbia
Gad Getz
Gad Getz Broad Institute
Marco A. Marra
Marco A. Marra University of British Columbia
Samuel Aparicio
Samuel Aparicio University of British Columbia
Rameen Beroukhim
Rameen Beroukhim Harvard University
Todd R. Golub
Todd R. Golub Harvard University
Andrew D. Cherniack
Andrew D. Cherniack Broad Institute
Eliezer M. Van Allen
Eliezer M. Van Allen Harvard University

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