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Genetics

D-Index
91
Citations
99200
World Ranking
1017
National Ranking
30

Overview

Martin Hirst is a researcher affiliated with the University of British Columbia in Canada. Their work spans a range of areas within biochemistry, genetics, molecular biology, and medicine, reflected by extensive publications in these fields.

The primary fields of study for Martin Hirst include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

The scientist's subfields of focus cover:

  • Molecular Biology
  • Immunology
  • Cancer Research
  • Pulmonary and Respiratory Medicine
  • Hematology

Martin Hirst's main research topics consist of:

  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Single-cell and spatial transcriptomics
  • Cancer Genomics and Diagnostics
  • Chromatin Remodeling and Cancer
  • Genomics and Chromatin Dynamics
  • Acute Myeloid Leukemia Research

Notable recent papers authored by Martin Hirst cover diverse themes within immunology, genomics, and epigenetics:

  • Butyrate Shapes Immune Cell Fate and Function in Allergic Asthma, 2021, Frontiers in Immunology
  • The ENCODE Uniform Analysis Pipelines, 2023, bioRxiv (Cold Spring Harbor Laboratory)
  • Megabase-scale methylation phasing using nanopore long reads and NanoMethPhase, 2021, Genome Biology
  • Human placental cytotrophoblast epigenome dynamics over gestation and alterations in placental disease, 2021, Developmental Cell
  • Altered microRNA expression links IL6 and TNF-induced inflammaging with myeloid malignancy in humans and mice, 2020, Blood

Frequent coauthors collaborating with Martin Hirst include:

  • Michelle Moksa
  • Misha Bilenky
  • Annaïck Carles
  • Connie J. Eaves
  • Steven J.M. Jones

Martin Hirst's research has been published in multiple venues, with repeated contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • Cancer Research
  • Epigenomics
  • Experimental Hematology

Best Publications

  • Comprehensive molecular portraits of human breast tumours

    Daniel C. Koboldt;Robert S. Fulton;Michael D. McLellan;Heather Schmidt

  • The cancer genome atlas pan-cancer analysis project

    John N Weinstein;John N Weinstein;Eric A. Collisson;Gordon B Mills;Kenna R Mills Shaw;Kenna R Mills Shaw

  • Comprehensive molecular characterization of human colon and rectal cancer

    Donna M. Muzny;Matthew N. Bainbridge;Kyle Chang;Huyen H. Dinh

  • Integrative analysis of 111 reference human epigenomes

    Anshul Kundaje;Wouter Meuleman;Wouter Meuleman;Jason Ernst

  • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

    Timothy J. Ley;Christopher Miller;Li Ding;Benjamin J. Raphael

  • Comprehensivemolecular characterization of clear cell renal cell carcinoma

    Chad J. Creighton;Margaret Morgan;Preethi H. Gunaratne;Preethi H. Gunaratne;David A. Wheeler

  • Comprehensive genomic characterization of squamous cell lung cancers

    Peter S. Hammerman;Doug Voet;Michael S. Lawrence;Douglas Voet

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • The clonal and mutational evolution spectrum of primary triple-negative breast cancers

    Sohrab P. Shah;Andrew Roth;Rodrigo Goya;Arusha Oloumi

  • Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

    Morin Rd;Johnson Na;Severson Tm;Mungall Aj

  • Conserved role of intragenic DNA methylation in regulating alternative promoters

    Alika K. Maunakea;Raman P. Nagarajan;Mikhail Bilenky;Tracy J. Ballinger

  • ARID1A mutations in endometriosis-associated ovarian carcinomas.

    Kimberly C. Wiegand;Sohrab P. Shah;Osama M. Al-Agha;Yongjun Zhao

  • The NIH Roadmap Epigenomics Mapping Consortium

    Bradley E Bernstein;John A Stamatoyannopoulos;Joseph F Costello;Bing Ren

  • Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

    Ryan D Morin;María Méndez-Lago;Andrew J Mungall;Rodrigo Goya

  • Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing

    Gordon Robertson;Martin Hirst;Matthew Bainbridge;Misha Bilenky

  • Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma

    Brett E. Johnson;Tali Mazor;Chibo Hong;Michael Barnes

  • Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells.

    Ryan D Morin;Michael D O'Connor;Malachi Griffith;Florian Kuchenbauer

  • Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

    Sohrab P. Shah;Ryan D. Morin;Jaswinder Khattra;Leah Prentice

  • The genetic landscape of high-risk neuroblastoma

    Trevor J Pugh;Olena Morozova;Edward F Attiyeh;Edward F Attiyeh;Shahab Asgharzadeh;Shahab Asgharzadeh

  • The Cancer Genome Atlas Pan-Cancer analysis project

    Kyle Chang;Chad J Creighton;Caleb Davis;Lawrence Donehower

Frequent Co-Authors

Marco A. Marra
Marco A. Marra University of British Columbia
Steven J.M. Jones
Steven J.M. Jones University of British Columbia
Connie J. Eaves
Connie J. Eaves University of British Columbia
Samuel Aparicio
Samuel Aparicio University of British Columbia
Richard A. Moore
Richard A. Moore BC Cancer Agency
Ryan D. Morin
Ryan D. Morin Simon Fraser University
Andrew J. Mungall
Andrew J. Mungall BC Cancer Agency
Inanc Birol
Inanc Birol University of British Columbia
Robert A. Holt
Robert A. Holt BC Cancer Research Institute
Sohrab P. Shah
Sohrab P. Shah Memorial Sloan Kettering Cancer Center

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