D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 75 Citations 14,573 215 World Ranking 14799 National Ranking 7594

Research.com Recognitions

Awards & Achievements

2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Internal medicine
  • Enzyme

His primary areas of investigation include Internal medicine, Endocrinology, Testosterone, Leydig cell and Androgen. Spermatogenesis, Luteinizing hormone, Gonadotropin, Testicle and Hormone are the core of his Internal medicine study. His studies in Endocrinology integrate themes in fields like Apoptosis, Azoospermia and Cellular differentiation.

He combines subjects such as Steroid hormone, Andrology, Gestation, Steroid and Metabolism with his study of Testosterone. His studies deal with areas such as Endoplasmic reticulum, Superoxide and Free-radical theory of aging as well as Leydig cell. The Androgen study which covers Toxicity that intersects with Oral administration, Pituitary gland, Seminal vesicle and Ingestion.

His most cited work include:

  • Phthalate-induced Leydig cell hyperplasia is associated with multiple endocrine disturbances. (286 citations)
  • Kinetic studies on the development of the adult population of leydig cells in testes of the pubertal rat (275 citations)
  • Comparison of spontaneous and experimentally induced canine prostatic hyperplasia. (256 citations)

What are the main themes of his work throughout his whole career to date?

Barry R. Zirkin focuses on Internal medicine, Endocrinology, Testosterone, Leydig cell and Androgen. Barry R. Zirkin works mostly in the field of Internal medicine, limiting it down to topics relating to In vivo and, in certain cases, In vitro, as a part of the same area of interest. As a part of the same scientific study, Barry R. Zirkin usually deals with the Endocrinology, concentrating on Mitochondrion and frequently concerns with Steroid and Steroid biosynthesis.

His research in Testosterone tackles topics such as In utero which are related to areas like Endocrine disruptor. His work is dedicated to discovering how Leydig cell, Endoplasmic reticulum are connected with Secretion and Ultrastructure and other disciplines. The Androgen study combines topics in areas such as Androgen receptor and Seminiferous tubule fluid.

He most often published in these fields:

  • Internal medicine (78.22%)
  • Endocrinology (77.33%)
  • Testosterone (41.78%)

What were the highlights of his more recent work (between 2010-2021)?

  • Internal medicine (78.22%)
  • Endocrinology (77.33%)
  • Leydig cell (40.00%)

In recent papers he was focusing on the following fields of study:

Barry R. Zirkin mainly focuses on Internal medicine, Endocrinology, Leydig cell, Testosterone and Luteinizing hormone. As part of his studies on Internal medicine, Barry R. Zirkin often connects relevant subjects like Cell biology. His biological study spans a wide range of topics, including In utero, Steroidogenic acute regulatory protein, Mitochondrion and In vivo.

His Leydig cell research is multidisciplinary, relying on both Cholesterol side-chain cleavage enzyme, Pregnenolone, Cholesterol, Spermatogenesis and Intracellular. He studied Testosterone and Androgen that intersect with Mortality rate and Male mice. His Luteinizing hormone research is multidisciplinary, incorporating perspectives in Endocrine system, Receptor, Single injection, BROWN NORWAY and Ethane dimethanesulfonate.

Between 2010 and 2021, his most popular works were:

  • Fetal origin of endocrine dysfunction in the adult: the phthalate model. (90 citations)
  • Leydig cells: formation, function, and regulation. (81 citations)
  • Translocator protein-mediated pharmacology of cholesterol transport and steroidogenesis (75 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

Barry R. Zirkin spends much of his time researching Internal medicine, Endocrinology, Leydig cell, Luteinizing hormone and Mitochondrion. His research brings together the fields of In utero and Internal medicine. His research in Endocrinology is mostly focused on Steroid biosynthesis.

The various areas that he examines in his Leydig cell study include Cellular differentiation, Androgen, Stem cell, Cholesterol and Intracellular. His studies in Luteinizing hormone integrate themes in fields like Receptor, Oxidative stress and Steroidogenic acute regulatory protein. His study on Mitochondrion also encompasses disciplines like

  • Steroid that connect with fields like In vivo and In vitro,
  • Cytosol and related Function and Apoptosis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Phthalate-induced Leydig cell hyperplasia is associated with multiple endocrine disturbances.

Benson T. Akingbemi;Renshan Ge;Gary R. Klinefelter;Barry R. Zirkin.
Proceedings of the National Academy of Sciences of the United States of America (2004)

455 Citations

Kinetic studies on the development of the adult population of Leydig cells in testes of the pubertal rat.

Matthew P. Hardy;Barry R. Zirkin;Larry L. Ewing.
Endocrinology (1989)

426 Citations

Maintenance of advanced spermatogenic cells in the adult rat testis: quantitative relationship to testosterone concentration within the testis.

Barry R. Zirkin;Rosemary Santulli;Caleb A. Awoniyi;Larry L. Ewing.
Endocrinology (1989)

401 Citations

Comparison of spontaneous and experimentally induced canine prostatic hyperplasia.

D P DeKlerk;D S Coffey;L L Ewing;I R McDermott.
Journal of Clinical Investigation (1979)

390 Citations

Modulation of Rat Leydig Cell Steroidogenic Function by Di(2-Ethylhexyl)Phthalate

Benson T. Akingbemi;Robert T. Youker;Chantal M. Sottas;Renshan Ge.
Biology of Reproduction (2001)

381 Citations

Regulation of Leydig Cell Steroidogenic Function During Aging

Barry R. Zirkin;Haolin Chen.
Biology of Reproduction (2000)

323 Citations

Leydig cells: From stem cells to aging.

Haolin Chen;Ren Shan Ge;Barry R. Zirkin.
Molecular and Cellular Endocrinology (2009)

297 Citations

The role of disulfide bond reduction during mammalian sperm nuclear decondensation in vivo

Sally D. Perreault;Robert A. Wolff;Barry R. Zirkin.
Developmental Biology (1984)

286 Citations

In search of rat stem Leydig cells: Identification, isolation, and lineage-specific development

Ren Shan Ge;Qiang Dong;Chantal M. Sottas;Vassilios Papadopoulos.
Proceedings of the National Academy of Sciences of the United States of America (2006)

285 Citations

Testosterone secretion by rat, rabbit, guinea pig, dog, and hamster testes perfused in vitro: correlation with Leydig cell mass.

L. L. Ewing;B. R. Zirkin;R. C. Cochran;N. Kromann.
Endocrinology (1979)

273 Citations

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