His primary scientific interests are in Biochemistry, Reactive oxygen species, Superoxide, Oxidative stress and Mitochondrion. His research on Biochemistry frequently connects to adjacent areas such as Carcinogenesis. His studies deal with areas such as Signal transduction, Protein kinase C and Hydrogen peroxide as well as Carcinogenesis.
Michael A. Trush combines subjects such as Acute promyelocytic leukemia, Enzyme complex, Bryostatin 1, Arsenic and Arsenic biochemistry with his study of Reactive oxygen species. His biological study spans a wide range of topics, including Xanthine oxidase, Cytochrome c, Xanthine, Molecular biology and Glucose oxidase. His research investigates the connection between Molecular biology and topics such as Viability assay that intersect with problems in Glutathione.
His primary areas of investigation include Biochemistry, Reactive oxygen species, Superoxide, Glutathione and Molecular biology. His work deals with themes such as Toxicity and Bone marrow, which intersect with Biochemistry. His research in Reactive oxygen species intersects with topics in Oxidative stress, Oxidative phosphorylation and Hydroxyl radical.
His Superoxide study combines topics in areas such as Chemiluminescence, Mitochondrion and Myeloperoxidase. As a part of the same scientific study, Michael A. Trush usually deals with the Mitochondrion, concentrating on Internal medicine and frequently concerns with Respiratory chain. The various areas that Michael A. Trush examines in his Glutathione study include Butylated hydroxyanisole and Antioxidant.
Michael A. Trush focuses on Cell biology, Reactive oxygen species, Environmental health, Mitochondrion and Oxidative stress. His Cell biology study combines topics from a wide range of disciplines, such as Ecology, Oxidative damage, Superoxide and NAD+ kinase. In his research, Drug, Enhancer and Immunology is intimately related to Cell, which falls under the overarching field of Reactive oxygen species.
Mitochondrion is the subject of his research, which falls under Biochemistry. Biochemistry and Chemiluminescence are commonly linked in his work. The Oxidative stress study which covers Activator that intersects with In vivo.
The scientist’s investigation covers issues in Reactive oxygen species, Cell biology, Superoxide, Mitochondrion and Oxidative stress. His study in Superoxide dismutase extends to Cell biology with its themes. He has researched Superoxide in several fields, including Mitochondrial ROS, Molecular biology, Flow cytometry, Nitric oxide and Intracellular.
His research integrates issues of Extracellular, Cancer cell, Peroxynitrite and Free-radical theory of aging in his study of Mitochondrion. Redox is closely connected to Pharmacology in his research, which is encompassed under the umbrella topic of Oxidative stress. The subject of his Rotenone research is within the realm of Biochemistry.
Role of quinones in toxicology.
Judy L. Bolton;Michael A. Trush;Trevor M. Penning;Glenn Dryhurst.
Chemical Research in Toxicology (2000)
Somatic mutations of the mitochondrial genome in human colorectal tumours
Kornelia Polyak;Kornelia Polyak;Yunbo Li;Hong Zhu;Christoph Lengauer.
Nature Genetics (1998)
Diphenyleneiodonium, an NAD(P)H oxidase inhibitor, also potently inhibits mitochondrial reactive oxygen species production.
Yunbo Li;Michael A. Trush.
Biochemical and Biophysical Research Communications (1998)
Validation of Lucigenin (Bis-N-methylacridinium) as a Chemilumigenic Probe for Detecting Superoxide Anion Radical Production by Enzymatic and Cellular Systems*
Yunbo Li;Hong Zhu;Periannan Kuppusamy;Valerie Roubaud.
Journal of Biological Chemistry (1998)
An overview of the relationship between oxidative stress and chemical carcinogenesis.
Michael A. Trush;Thomas W. Kensler.
Free Radical Biology and Medicine (1991)
Mitochondrial adaptations to obesity-related oxidant stress.
ShiQi Yang;Hong Zhu;Yunbo Li;HuiZhi Lin.
Archives of Biochemistry and Biophysics (2000)
Metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-diol by human cytochrome P450 1B1.
James H. Kim;Kevin H. Stansbury;Nigel J. Walker;Michael A. Trush.
Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide
Rajesh K. Thimmulappa;Catherine Scollick;Kassim Traore;Melinda Yates.
Biochemical and Biophysical Research Communications (2006)
Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1α
Zheqing Cai;Hua Zhong;Marta Bosch-Marce;Karen Fox-Talbot.
Cardiovascular Research (2007)
 The generation of chemiluminescence (CL) by phagocytic cells
Michael A. Trush;Mark E. Wilson;Knox van Dyke.
Methods in Enzymology (1978)
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