His scientific interests lie mostly in Genetics, Genome, Cancer research, Gene and DNA methylation. Robert A. Holt focuses mostly in the field of Genome, narrowing it down to topics relating to Computational biology and, in certain cases, Shotgun sequencing. His studies in Cancer research integrate themes in fields like KRAS, microRNA, CDKN2A, Carcinoma and Adenocarcinoma.
In his study, Expressed sequence tag, Haplotype, Intron, Homology and Exon is inextricably linked to Anopheles gambiae, which falls within the broad field of Gene. As part of one scientific family, he deals mainly with the area of DNA methylation, narrowing it down to issues related to the Exome, and often 1p/19q Codeletion, Glioma, Claudin-Low and Genetic heterogeneity. The concepts of his Genome size study are interwoven with issues in Gene density, Genome evolution, Genome project and Horizontal gene transfer.
Robert A. Holt focuses on Genetics, Gene, Genome, Cancer research and Computational biology. His study in Human genome, Sequence analysis, Gene expression profiling, DNA sequencing and Genomic library is carried out as part of his Genetics studies. His work on Promoter, microRNA and Gene expression as part of general Gene research is often related to Expression vector, thus linking different fields of science.
His study in Whole genome sequencing, Genomics, Genome project, Reference genome and Expressed sequence tag are all subfields of Genome. He combines subjects such as Cancer, DNA methylation, Mutation, Transcriptome and Immune system with his study of Cancer research. His research in Computational biology intersects with topics in RNA, Reporter gene, T-cell receptor and Sequence assembly.
Robert A. Holt mostly deals with Cancer research, Cancer, Gene, T cell and Genetics. His Cancer research research includes themes of DNA methylation, Immune system, microRNA, Disease and Colorectal cancer. He interconnects Missense mutation, Immunology, Oncology and Somatic cell in the investigation of issues within Cancer.
As part of the same scientific family, Robert A. Holt usually focuses on Gene, concentrating on Adenocarcinoma and intersecting with Inflammation. Much of his study explores Genetics relationship to Brain research. Robert A. Holt studies Whole genome sequencing which is a part of Genome.
Robert A. Holt spends much of his time researching Cancer research, Gene, microRNA, Genetics and DNA methylation. The various areas that Robert A. Holt examines in his Cancer research study include Oncogene, Immune system, KRAS, Neuroblastoma RAS viral oncogene homolog and Epigenetics. The study incorporates disciplines such as Retina and Central nervous system in addition to Gene.
His Genome and Mutant study, which is part of a larger body of work in Genetics, is frequently linked to Threatened species, bridging the gap between disciplines. His Genome research includes elements of Germline mutation, Lithobates, Amphibian, True frogs and Computational biology. His work in DNA methylation addresses subjects such as Mutation, which are connected to disciplines such as Ovarian tumor, Antigen and Ovarian cancer.
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Comprehensive molecular portraits of human breast tumours
Daniel C. Koboldt;Robert S. Fulton;Michael D. McLellan;Heather Schmidt.
The genome sequence of Drosophila melanogaster
M. D. Adams;S. E. Celniker;R. A. Holt;C. A. Evans.
Comprehensive molecular characterization of human colon and rectal cancer
Donna M. Muzny;Matthew N. Bainbridge;Kyle Chang;Huyen H. Dinh.
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
Timothy J. Ley;Christopher Miller;Li Ding;Benjamin J. Raphael.
The New England Journal of Medicine (2013)
The cancer genome atlas pan-cancer analysis project
John N Weinstein;John N Weinstein;Eric A. Collisson;Gordon B Mills;Kenna R Mills Shaw;Kenna R Mills Shaw.
Nature Genetics (2013)
The genome of black cottonwood, Populus trichocarpa (Torr. & Gray)
G. A. Tuskan;G. A. Tuskan;S. DiFazio;S. DiFazio;S. Jansson;J. Bohlmann.
Comprehensive molecular characterization of gastric adenocarcinoma
Adam J. Bass;Vesteinn Thorsson;Ilya Shmulevich;Sheila M. Reynolds.
Comprehensive genomic characterization of head and neck squamous cell carcinomas
Michael S. Lawrence;Carrie Sougnez;Lee Lichtenstein;Kristian Cibulskis.
Comprehensivemolecular characterization of clear cell renal cell carcinoma
Chad J. Creighton;Margaret Morgan;Preethi H. Gunaratne;Preethi H. Gunaratne;David A. Wheeler.
Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network
Eric A. Collisson;Joshua D. Campbell;Angela N. Brooks;Angela N. Brooks;Alice H. Berger.
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