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Genetics

D-Index
109
Citations
190205
World Ranking
541
National Ranking
18

Medicine

D-Index
111
Citations
200259
World Ranking
5208
National Ranking
205

Overview

Robert A. Holt is affiliated with the BC Cancer Research Institute in Canada. Their primary research spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a concentration in Oncology, Immunology, Molecular Biology, Genetics, and Pathology and Forensic Medicine.

Their scientific work is focused on several main topics:

  • CAR-T cell therapy research
  • Cancer Immunotherapy and Biomarkers
  • Immune Cell Function and Interaction
  • Cancer Genomics and Diagnostics
  • Immunotherapy and Immune Responses
  • Gut microbiota and health
  • Virus-based gene therapy research

Recent publications include:

  • Pan-cancer analysis of advanced patient tumors reveals interactions between therapy and genomic landscapes, 2020, Nature Cancer
  • Characteristics of TCR Repertoire Associated With Successful Immune Checkpoint Therapy Responses, 2020, Frontiers in Immunology
  • Genome and Transcriptome Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Solid Tumors, 2020, Clinical Cancer Research
  • Tumor Infiltrating Effector Memory Antigen-Specific CD8+ T Cells Predict Response to Immune Checkpoint Therapy, 2020, Frontiers in Immunology
  • Direct in vivo CAR T cell engineering, 2024, Trends in Pharmacological Sciences

Their work has been frequently published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Frontiers in Immunology
  • Annals of the Rheumatic Diseases
  • Journal of the Endocrine Society

Frequent collaborators in their research include:

  • Scott D. Brown
  • Steven J.M. Jones
  • Andrew J. Mungall
  • Miruna Balasundaram
  • Eric Chuah

Best Publications

  • The Sequence of the Human Genome

    J. Craig Venter;Mark D. Adams;Eugene W. Myers;Peter W. Li

  • Comprehensive molecular portraits of human breast tumours

    Daniel C. Koboldt;Robert S. Fulton;Michael D. McLellan;Heather Schmidt

  • The cancer genome atlas pan-cancer analysis project

    John N Weinstein;John N Weinstein;Eric A. Collisson;Gordon B Mills;Kenna R Mills Shaw;Kenna R Mills Shaw

  • The genome sequence of Drosophila melanogaster

    M. D. Adams;S. E. Celniker;R. A. Holt;C. A. Evans

  • Comprehensive molecular characterization of human colon and rectal cancer

    Donna M. Muzny;Matthew N. Bainbridge;Kyle Chang;Huyen H. Dinh

  • Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia

    Timothy J. Ley;Christopher Miller;Li Ding;Benjamin J. Raphael

  • Comprehensive molecular characterization of gastric adenocarcinoma

    Adam J. Bass;Vesteinn Thorsson;Ilya Shmulevich;Sheila M. Reynolds

  • Integrated genomic characterization of endometrial carcinoma

    Gad Getz;Stacey B. Gabriel;Kristian Cibulskis;Eric Lander

  • Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

    Eric A. Collisson;Joshua D. Campbell;Angela N. Brooks;Angela N. Brooks;Alice H. Berger

  • The genome of black cottonwood, Populus trichocarpa (Torr. & Gray)

    G. A. Tuskan;G. A. Tuskan;S. DiFazio;S. DiFazio;S. Jansson;J. Bohlmann

  • Comprehensive genomic characterization of head and neck squamous cell carcinomas

    Michael S. Lawrence;Carrie Sougnez;Lee Lichtenstein;Kristian Cibulskis

  • The Immune Landscape of Cancer

    Vésteinn Thorsson;David L Gibbs;Scott D Brown;Denise Wolf

  • Comprehensivemolecular characterization of clear cell renal cell carcinoma

    Chad J. Creighton;Margaret Morgan;Preethi H. Gunaratne;Preethi H. Gunaratne;David A. Wheeler

  • Comprehensive genomic characterization of squamous cell lung cancers

    Peter S. Hammerman;Doug Voet;Michael S. Lawrence;Douglas Voet

  • Comprehensive molecular characterization of urothelial bladder carcinoma

    John N Weinstein;Rehan Akbani;Bradley McIntosh Broom;Wenyi Wang

  • Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.

    Daniel J. Brat;Roel G.W. Verhaak;Kenneth D. Aldape;W. K.Alfred Yung

  • The Molecular Taxonomy of Primary Prostate Cancer

    Adam Abeshouse;Jaeil Ahn;Rehan Akbani;Adrian Ally

  • The Genome Sequence of the SARS-associated Coronavirus

    Marco A. Marra;Steven J. M. Jones;Caroline R. Astell;Robert A. Holt

  • The Cancer Genome Atlas Pan-Cancer analysis project

    Kyle Chang;Chad J Creighton;Caleb Davis;Lawrence Donehower

  • The genome of black cottonwood, Populus trichocarpa (Torr. & Gray) - eScholarship

    G.A. Tuskan;S. DiFazio;S. Jansson;J. Bohlmann

Frequent Co-Authors

Steven J.M. Jones
Steven J.M. Jones University of British Columbia
Marco A. Marra
Marco A. Marra University of British Columbia
Richard A. Moore
Richard A. Moore BC Cancer Agency
Andrew J. Mungall
Andrew J. Mungall BC Cancer Agency
Jacqueline E. Schein
Jacqueline E. Schein BC Cancer Agency
Rameen Beroukhim
Rameen Beroukhim Harvard University
Andrew D. Cherniack
Andrew D. Cherniack Broad Institute
Inanc Birol
Inanc Birol University of British Columbia
Matthew Meyerson
Matthew Meyerson Harvard University
John N. Weinstein
John N. Weinstein The University of Texas MD Anderson Cancer Center

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