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Simona Capsoni

Simona Capsoni

D-Index & Metrics

Neuroscience

D-Index
45
Citations
6142
World Ranking
7006
National Ranking
367

Overview

Simona Capsoni is affiliated with the University of Milan in Italy and conducts research primarily in the fields of Neuroscience and Medicine. Their work spans several subfields, including Cellular and Molecular Neuroscience, Physiology, Developmental Neuroscience, Neurology, and Molecular Biology. The main topics addressed in their research focus on nerve injury and regeneration, neurogenesis and neuroplasticity mechanisms, neuroinflammation and neurodegeneration mechanisms, Alzheimer's disease research and treatments, axon guidance and neuronal signaling, restless legs syndrome research, and broader aspects of neuroscience and neural engineering.

Among the recent publications associated with their research are:

  • Enteric α-synuclein impairs intestinal epithelial barrier through caspase-1-inflammasome signaling in Parkinson's disease before brain pathology, 2022, npj Parkinson s Disease
  • Graphene Promotes Axon Elongation through Local Stall of Nerve Growth Factor Signaling Endosomes, 2020, Nano Letters
  • Intranasal delivery of BDNF rescues memory deficits in AD11 mice and reduces brain microgliosis, 2020, Aging Clinical and Experimental Research
  • Unraveling the Role of Dopaminergic and Calretinin Interneurons in the Olfactory Bulb, 2021, Frontiers in Neural Circuits
  • Understanding pain perception through genetic painlessness diseases: The role of NGF and proNGF, 2021, Pharmacological Research

Frequent coauthors collaborating with Simona Capsoni include Antonino Cattaneo, Giovanna Testa, Alexia Tiberi, Ivan Arisi, and Rossella Brandi. The scientist commonly publishes in venues such as npj Parkinson s Disease, Cells, bioRxiv (Cold Spring Harbor Laboratory), Nano Letters, and Aging Clinical and Experimental Research.

Their research contributes to understanding mechanisms of neurodegenerative diseases, neuronal signaling, and neuroplasticity, with attention to cellular processes and molecular pathways relevant to nerve damage and repair. Specific investigations involve aspects such as the role of α-synuclein in intestinal epithelial barriers related to Parkinson's disease and the use of neurotrophic factors like BDNF in models of cognitive impairment.

Best Publications

  • Alzheimer-like neurodegeneration in aged antinerve growth factor transgenic mice

    Simona Capsoni;Gabriele Ugolini;Alessandro Comparini;Francesca Ruberti

  • Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice

    Roberta De Rosa;Addys Ancheta Garcia;Chiara Braschi;Simona Capsoni

  • Phenotypic knockout of nerve growth factor in adult transgenic mice reveals severe deficits in basal forebrain cholinergic neurons, cell death in the spleen, and skeletal muscle dystrophy.

    F Ruberti;Simona Capsoni;A Comparini;E Di Daniel

  • Nerve growth factor and galantamine ameliorate early signs of neurodegeneration in anti-nerve growth factor mice

    Simona Capsoni;Sabina Giannotta;Antonino Cattaneo

  • Receptor for Advanced Glycation End Product-Dependent Activation of p38 Mitogen-Activated Protein Kinase Contributes to Amyloid-β-Mediated Cortical Synaptic Dysfunction

    Nicola Origlia;Massimo Righi;Simona Capsoni;Antonino Cattaneo

  • A small molecule targeting the multifactorial nature of Alzheimer's disease.

    Andrea Cavalli;Maria Laura Bolognesi;Simona Capsoni;Vincenza Andrisano

  • Gene expression biomarkers in the brain of a mouse model for Alzheimer's disease: Mining of microarray data by logic classification and feature selection

    Ivan Arisi;Mara D'Onofrio;Rossella Brandi;Armando Felsani

  • On the molecular basis linking nerve growth factor (NGF) to Alzheimer's disease

    Simona Capsoni;Antonino Cattaneo

  • Environmental enrichment delays the onset of memory deficits and reduces neuropathological hallmarks in a mouse model of Alzheimer-like neurodegeneration.

    Nicoletta Berardi;Chiara Braschi;Simona Capsoni;Antonino Cattaneo

  • Towards non invasive nerve growth factor therapies for Alzheimer's disease.

    Antonino Cattaneo;Simona Capsoni;Francesca Paoletti

  • Interaction between NH2-tau fragment and Aβ in Alzheimer's disease mitochondria contributes to the synaptic deterioration

    Unknown

  • Beta-amyloid plaques in a model for sporadic Alzheimer's disease based on transgenic anti-nerve growth factor antibodies.

    Simona Capsoni;Sabina Giannotta;Antonino Cattaneo

  • Development of a non invasive NGF-based therapy for Alzheimer's disease.

    Sonia Covaceuszach;Simona Capsoni;Gatsuella Ugolini;F. Spirito

  • Taking Pain Out of NGF: A “Painless” NGF Mutant, Linked to Hereditary Sensory Autonomic Neuropathy Type V, with Full Neurotrophic Activity

    Simona Capsoni;Sonia Covaceuszach;Sara Marinelli;Marcello Ceci

  • Melatonin signal transduction and mechanism of action in the central nervous system: using the rabbit cortex as a model.

    B. Stankov;G. Biella;C. Panara;V. Lucini

  • Autoradiographic Localization of Putative Melatonin Receptors in the Brains of Two Old World Primates: Cercopithecus Aethiops and Papio Ursinus

    B. Stankov;S. Capsoni;V. Lucini;J. Fauteck

  • Characterization of melatonin receptors and signal transduction system in rat arteries forming the circle of Willis

    S. Capsoni;Mohan Viswanathan;A. M. De Oliveira;J. M. Saavedra

  • Endogenous Aβ causes cell death via early tau hyperphosphorylation.

    G. Amadoro;V. Corsetti;M.T. Ciotti;F. Florenzano

  • NGF steers microglia toward a neuroprotective phenotype.

    Caterina Rizzi;Alexia Tiberi;Michela Giustizieri;Maria Cristina Marrone

  • Intranasal delivery of therapeutic proteins for neurological diseases.

    Francesca Malerba;Francesca Paoletti;Simona Capsoni;Antonino Cattaneo

  • Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegeneration

    Simona Capsoni;Cecilia Tiveron;Domenico Vignone;Gianluca Amato

  • Functional Blockade of Tyrosine Kinase A in the Rat Basal Forebrain by a Novel Antagonistic Anti-Receptor Monoclonal Antibody

    Antonino Cattaneo;Simona Capsoni;Elisa Margotti;Massimo Righi

Frequent Co-Authors

Luciano Domenici
Luciano Domenici University of L'Aquila
Nicoletta Berardi
Nicoletta Berardi University of Florence
Enrico Tongiorgi
Enrico Tongiorgi University of Trieste
Flaminia Pavone
Flaminia Pavone National Academies of Sciences, Engineering, and Medicine
Ottavio Arancio
Ottavio Arancio Columbia University
Lamberto Maffei
Lamberto Maffei National Research Council (CNR)
Morten Møller
Morten Møller University of Copenhagen
Enrico Cherubini
Enrico Cherubini International School for Advanced Studies
Fernando M.A. Corrêa
Fernando M.A. Corrêa Universidade de São Paulo
Ann Marie Schmidt
Ann Marie Schmidt New York University

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