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Vincenza Andrisano

Vincenza Andrisano

D-Index & Metrics

Chemistry

D-Index
69
Citations
14291
World Ranking
6329
National Ranking
139

Overview

Vincenza Andrisano is affiliated with the University of Bologna in Italy. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on Pharmacology, Molecular Biology, Organic Chemistry, Physiology, and Computational Theory and Mathematics as subfields.

The scientist's work extensively addresses topics related to cholinesterase and neurodegenerative diseases, Alzheimer's disease research and treatments, computational drug discovery methods, chemical synthesis and alkaloids, medicinal plants and neuroprotection, algal biology and biofuel production, and the synthesis and pharmacology of alkaloids.

Frequent publication venues for their research include:

  • Journal of Pharmaceutical and Biomedical Analysis
  • Journal of Medicinal Chemistry
  • European Journal of Medicinal Chemistry
  • ACS Chemical Neuroscience
  • Molecules

Notable recent papers by Vincenza Andrisano include:

  • "Glycogen Synthase Kinase 3β: A New Gold Rush in Anti-Alzheimer's Disease Multitarget Drug Discovery?", 2020, Journal of Medicinal Chemistry
  • "Discovery of a Potent Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase with Antioxidant Activity that Alleviates Alzheimer-like Pathology in Old APP/PS1 Mice", 2020, Journal of Medicinal Chemistry
  • "Multi-target neuroprotective effects of herbal medicines for Alzheimer's disease", 2022, Journal of Ethnopharmacology
  • "Targeting topoisomerase II with trypthantrin derivatives: Discovery of 7-((2-(dimethylamino)ethyl)amino)indolo[2,1-b]quinazoline-6,12-dione as an antiproliferative agent and to treat cancer", 2020, European Journal of Medicinal Chemistry
  • "Centrally Active Multitarget Anti-Alzheimer Agents Derived from the Antioxidant Lead CR-6", 2020, Journal of Medicinal Chemistry

The scientist has collaborated frequently with several co-authors, notably:

  • Angela De Simone
  • Serena Montanari
  • Lara Davani
  • Cristina Terenzi
  • Vincenzo Tumiatti

Vincenza Andrisano's contributions often intersect multiple disciplines involving computational and synthetic approaches to drug discovery, with particular attention to neurodegenerative diseases such as Alzheimer's. Their work on multitarget agents and herbal neuroprotection reflects a multidisciplinary approach combining chemistry, pharmacology, and computational methods.

Best Publications

  • β-Amyloid aggregation induced by human acetylcholinesterase: inhibition studies

    Manuela Bartolini;Carlo Bertucci;Vanni Cavrini;Vincenza Andrisano

  • Insight Into the Kinetic of Amyloid β (1–42) Peptide Self-Aggregation: Elucidation of Inhibitors’ Mechanism of Action

    Manuela Bartolini;Carlo Bertucci;Maria Laura Bolognesi;Andrea Cavalli

  • 3-(4-{[Benzyl(methyl)amino]methyl}phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) Inhibits Both Acetylcholinesterase and Acetylcholinesterase-Induced β-Amyloid Aggregation: A Dual Function Lead for Alzheimer's Disease Therapy§

    Lorna Piazzi;Angela Rampa;Alessandra Bisi;Silvia Gobbi

  • Multi-target-directed drug design strategy: from a dual binding site acetylcholinesterase inhibitor to a trifunctional compound against Alzheimer's disease.

    Maria Laura Bolognesi;Andrea Cavalli;Luca Valgimigli;Manuela Bartolini

  • Rational approach to discover multipotent anti-Alzheimer drugs.

    Michela Rosini;Vincenza Andrisano;Manuela Bartolini;Maria L. Bolognesi

  • Multi-target-directed coumarin derivatives: hAChE and BACE1 inhibitors as potential anti-Alzheimer compounds.

    Lorna Piazzi;Andrea Cavalli;Francesco Colizzi;Federica Belluti

  • Design, synthesis, and biological evaluation of dual binding site acetylcholinesterase inhibitors: new disease-modifying agents for Alzheimer's disease.

    Pilar Munoz-Ruiz;Laura Rubio;Esther Garcia-Palomero;Isabel Dorronsoro

  • Novel Donepezil-Based Inhibitors of Acetyl- and Butyrylcholinesterase and Acetylcholinesterase-Induced β-Amyloid Aggregation

    Pelayo Camps;Xavier Formosa;Carles Galdeano;Tània Gómez

  • Inhibition of acetylcholinesterase, beta-amyloid aggregation, and NMDA receptors in Alzheimer's disease: a promising direction for the multi-target-directed ligands gold rush.

    Michela Rosini;Elena Simoni;Manuela Bartolini;Andrea Cavalli

  • Pyrano[3,2-c]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds

    Pelayo Camps;Xavier Formosa;Carles Galdeano;Diego Muñoz-Torrero

  • A small molecule targeting the multifactorial nature of Alzheimer's disease.

    Andrea Cavalli;Maria Laura Bolognesi;Simona Capsoni;Vincenza Andrisano

  • Benzofuran-Based Hybrid Compounds for the Inhibition of Cholinesterase Activity, β Amyloid Aggregation, and Aβ Neurotoxicity

    Stefano Rizzo;Céline Rivière;Lorna Piazzi;Alessandra Bisi

  • SAR of 9-Amino-1,2,3,4-tetrahydroacridine-Based Acetylcholinesterase Inhibitors: Synthesis, Enzyme Inhibitory Activity, QSAR, and Structure-Based CoMFA of Tacrine Analogues

    Maurizio Recanatini;Andrea Cavalli;Federica Belluti;Lorna Piazzi

  • Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.

    José Marco-Contelles;Rafael León;Cristóbal de los Ríos;Abdelouahid Samadi

  • Multitarget Drug Design Strategy: Quinone–Tacrine Hybrids Designed To Block Amyloid-β Aggregation and To Exert Anticholinesterase and Antioxidant Effects

    Eugenie Nepovimova;Elisa Uliassi;Jan Korabecny;Luis Emiliano Peña-Altamira

  • Novel Class of Quinone-Bearing Polyamines as Multi-Target-Directed Ligands To Combat Alzheimer's Disease

    Maria Laura Bolognesi;Rita Banzi;Manuela Bartolini;Andrea Cavalli

  • Strategies for the Inhibition of Protein Aggregation in Human Diseases

    Manuela Bartolini;Vincenza Andrisano

  • Analysis of ACE inhibitors in pharmaceutical dosage forms by derivative UV spectroscopy and liquid chromatography (HPLC)

    D Bonazzi;R Gotti;V Andrisano;V Cavrini

  • Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues.

    Maria Laura Bolognesi;Manuela Bartolini;Andrea Cavalli;Vincenza Andrisano

  • Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography.

    Xiaoming Zha;Doriano Lamba;Lili Zhang;Yinghan Lou

  • Propidium-Based Polyamine Ligands as Potent Inhibitors of Acetylcholinesterase and Acetylcholinesterase-Induced Amyloid-β Aggregation

    Maria Laura Bolognesi;Vincenza Andrisano;Manuela Bartolini;Rita Banzi

Frequent Co-Authors

Manuela Bartolini
Manuela Bartolini University of Bologna
Vanni Cavrini
Vanni Cavrini University of Bologna
Andrea Cavalli
Andrea Cavalli Italian Institute of Technology
Maria Laura Bolognesi
Maria Laura Bolognesi University of Bologna
Maurizio Recanatini
Maurizio Recanatini University of Bologna
Patrizia Hrelia
Patrizia Hrelia University of Bologna
F. Javier Luque
F. Javier Luque University of Barcelona
Romana Fato
Romana Fato University of Bologna
Ana Martínez
Ana Martínez Spanish National Research Council
José Marco-Contelles
José Marco-Contelles Spanish National Research Council

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