World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
55
Citations
10012
World Ranking
12212
National Ranking
7

Research.com Recognitions

  • Member of the European Academy of Sciences and Arts
  • Member of the European Academy of Sciences and Arts
  • Member of the European Academy of Sciences and Arts
  • Member of the European Academy of Sciences and Arts
  • Member of the European Academy of Sciences and Arts
  • Member of the European Academy of Sciences and Arts

Overview

Stanislav Gobec is affiliated with the University of Ljubljana in Slovenia and has contributed extensively to the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their research spans several subfields, including Molecular Biology, Pharmacology, Organic Chemistry, Computational Theory and Mathematics, and Oncology. This multidisciplinary approach supports their focus on various complex biological and chemical challenges within medical science.

The scientific topics Stanislav Gobec has explored include:

  • Cholinesterase and Neurodegenerative Diseases
  • Computational Drug Discovery Methods
  • Peptidase Inhibition and Analysis
  • Chemical Synthesis and Analysis
  • Alzheimer's Disease Research and Treatments
  • Click Chemistry and Applications
  • Medicinal Plants and Neuroprotection

Stanislav Gobec's publication record shows significant contributions to several scientific journals. Frequent venues where their work appears include:

  • European Journal of Medicinal Chemistry
  • ACS Omega
  • Biomedicine & Pharmacotherapy
  • Molecules
  • Bioorganic Chemistry

Some recent papers authored by Stanislav Gobec are:

  • Indoleamine and tryptophan 2,3-dioxygenases as important future therapeutic targets (2020) - Pharmacology & Therapeutics
  • Cell models for Alzheimer's and Parkinson's disease: At the interface of biology and drug discovery (2022) - Biomedicine & Pharmacotherapy
  • N-alkylpiperidine carbamates as potential anti-Alzheimer's agents (2020) - European Journal of Medicinal Chemistry
  • Stereoselective Activity of 1-Propargyl-4-styrylpiperidine-like Analogues That Can Discriminate between Monoamine Oxidase Isoforms A and B (2020) - Journal of Medicinal Chemistry
  • Analytical Techniques for Structural Characterization of Proteins in Solid Pharmaceutical Forms: An Overview (2021) - Pharmaceutics

The scientist frequently collaborates with a set of coauthors. The most common collaborators include:

  • Damijan Knez
  • Izidor Sosič
  • Matic Proj
  • Janko Kos
  • Xavier Brazzolotto

Stanislav Gobec has been recognized with the title of Member of the European Academy of Sciences and Arts.

Best Publications

  • Cytoplasmic steps of peptidoglycan biosynthesis.

    Hélène Barreteau;Andreja Kovač;Audrey Boniface;Matej Sova

  • Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor.

    Boris Brus;Urban Košak;Samo Turk;Anja Pišlar

  • Inhibitors of Cathepsin B

    Frlan R;Gobec S

  • Development of an in-vivo active reversible butyrylcholinesterase inhibitor

    Urban Košak;Boris Brus;Damijan Knez;Roman Šink

  • The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity

    Urban Košak;Boris Brus;Damijan Knez;Simon Žakelj

  • Endocrine Disruptome—An Open Source Prediction Tool for Assessing Endocrine Disruption Potential through Nuclear Receptor Binding

    Katra Kolšek;Janez Mavri;Marija Sollner Dolenc;Stanislav Gobec

  • False Positives in the Early Stages of Drug Discovery

    Roman Sink;Stanislav Gobec;Slavko Pečar;Anamarija Zega

  • A road map for prioritizing warheads for cysteine targeting covalent inhibitors.

    Péter Ábrányi-Balogh;László Petri;Tímea Imre;Péter Szijj

  • Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2,4-dione inhibitors of MurD ligase.

    Nace Zidar;Tihomir Tomašić;Roman Šink;Veronika Rupnik

  • Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F

    Martina Hrast;Izidor Sosič;Roman Šink;Stanislav Gobec

  • Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation.

    Dawid Panek;Anna Więckowska;Tomasz Wichur;Marek Bajda

  • Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1

    S. Gobec;P. Brozic;T. Lanisnik Rizner

  • Structural characterization and biological evaluation of a clioquinol-ruthenium complex with copper-independent antileukaemic activity†

    Martina Gobec;Jakob Kljun;Izidor Sosič;Irena Mlinarič-Raščan

  • Novel Mechanism of Cathepsin B Inhibition by Antibiotic Nitroxoline and Related Compounds

    Bojana Mirković;Miha Renko;Samo Turk;Izidor Sosič

  • Antifungal activity of cinnamic acid derivatives involves inhibition of benzoate 4-hydroxylase (CYP53).

    B. Korošec;M. Sova;S. Turk;N. Kraševec

  • Structural and Functional Characterization of Enantiomeric Glutamic Acid Derivatives as Potential Transition State Analogue Inhibitors of Murd Ligase.

    Miha Kotnik;Jan Humljan;Carlos Contreras-Martel;Marko Oblak

  • LiSiCA: A Software for Ligand-Based Virtual Screening and Its Application for the Discovery of Butyrylcholinesterase Inhibitors.

    Samo Lešnik;Tanja Štular;Boris Brus;Damijan Knez

  • Multi-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activities.

    Damijan Knez;Nicolas Coquelle;Anja Pišlar;Simon Žakelj

  • Design, synthesis, and evaluation of new thiadiazole-based direct inhibitors of enoyl acyl carrier protein reductase (InhA) for the treatment of tuberculosis.

    Roman Šink;Izidor Sosič;Matej Živec;Raquel Fernandez-Menendez

  • 5‐Benzylidenethiazolidin‐4‐ones as Multitarget Inhibitors of Bacterial Mur Ligases

    Tihomir Tomašić;Nace Zidar;Andreja Kovač;Samo Turk

  • Development of multifunctional, heterodimeric isoindoline-1,3-dione derivatives as cholinesterase and β-amyloid aggregation inhibitors with neuroprotective properties

    Natalia Guzior;Marek Bajda;Mirosław Skrok;Katarzyna Kurpiewska

  • Antibacterial and β‐Lactamase Inhibitory Activity of Monocyclic β‐Lactams

    Lena Decuyper;Marko Jukič;Izidor Sosič;Aleš Žula

  • Novel naphthalene-N-sulfonyl-D-glutamic acid derivatives as inhibitors of MurD, a key peptidoglycan biosynthesis enzyme.

    Jan Humljan;Miha Kotnik;Carlos Contreras-Martel;Didier Blanot

Frequent Co-Authors

Didier Blanot
Didier Blanot University of Paris-Saclay
Janko Kos
Janko Kos University of Ljubljana
Andréa Dessen
Andréa Dessen Brazilian Biosciences National Laboratory
Bernard Joris
Bernard Joris University of Liège
Dominique Mengin-Lecreulx
Dominique Mengin-Lecreulx University of Paris-Saclay
Florian Nachon
Florian Nachon Centre national de la recherche scientifique, CNRS
Ian Chopra
Ian Chopra University of Leeds
Gerhard Wolber
Gerhard Wolber Freie Universität Berlin
Alex J. O'Neill
Alex J. O'Neill University of Leeds
Christopher G. Dowson
Christopher G. Dowson University of Warwick

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