D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 54 Citations 8,952 156 World Ranking 2386 National Ranking 1153

Overview

What is he best known for?

The fields of study he is best known for:

  • Antibody
  • Immune system
  • Antigen

Ronald P. Taylor focuses on Antibody, Immunology, CD20, Complement system and Antigen. His Antibody study incorporates themes from Molecular biology, Cell biology, Immune system and Virology. His Molecular biology study combines topics from a wide range of disciplines, such as In vitro, Raji cell, Immunoglobulin G, iC3b and Cell killing.

The Rituximab, Monoclonal antibody and Immune complex research Ronald P. Taylor does as part of his general Immunology study is frequently linked to other disciplines of science, such as Immune adherence, therefore creating a link between diverse domains of science. His work deals with themes such as Monoclonal, Chronic lymphocytic leukemia, B cell and Immunotherapy, which intersect with CD20. Specifically, his work in Complement system is concerned with the study of Classical complement pathway.

His most cited work include:

  • Mechanisms of killing by anti-CD20 monoclonal antibodies. (452 citations)
  • Complement is activated by IgG hexamers assembled at the cell surface. (384 citations)
  • Rituximab Infusion Promotes Rapid Complement Depletion and Acute CD20 Loss in Chronic Lymphocytic Leukemia (281 citations)

What are the main themes of his work throughout his whole career to date?

Ronald P. Taylor mainly investigates Antibody, Immunology, Molecular biology, Monoclonal antibody and Complement system. His Antibody study combines topics in areas such as Biochemistry, DNA, Immune system, Antigen and Cell biology. His research in Molecular biology focuses on subjects like Immune complex, which are connected to Red blood cell.

His Monoclonal antibody research includes elements of Complement receptor 1, In vitro, Virology and Complement receptor. His work carried out in the field of Complement system brings together such families of science as Cytotoxic T cell and Cytotoxicity. The various areas that Ronald P. Taylor examines in his CD20 study include Trogocytosis, Complement-dependent cytotoxicity, Chronic lymphocytic leukemia and B cell.

He most often published in these fields:

  • Antibody (42.51%)
  • Immunology (36.44%)
  • Molecular biology (34.01%)

What were the highlights of his more recent work (between 2015-2021)?

  • Antibody (42.51%)
  • Complement system (22.27%)
  • Cell biology (10.93%)

In recent papers he was focusing on the following fields of study:

Ronald P. Taylor mainly focuses on Antibody, Complement system, Cell biology, Immunology and Cancer research. Ronald P. Taylor has included themes like Antigen and Cytotoxicity in his Antibody study. His Complement system study contributes to a more complete understanding of Immune system.

His Immunology research is multidisciplinary, relying on both Anemia and Kidney disease. His study looks at the relationship between Complement-dependent cytotoxicity and topics such as Molecular biology, which overlap with Intracellular. The study incorporates disciplines such as Cancer, Cytotoxic T cell and Chronic lymphocytic leukemia in addition to Monoclonal antibody.

Between 2015 and 2021, his most popular works were:

  • IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions (69 citations)
  • Cytotoxic mechanisms of immunotherapy: Harnessing complement in the action of anti-tumor monoclonal antibodies. (44 citations)
  • Antibodies That Efficiently Form Hexamers upon Antigen Binding Can Induce Complement-Dependent Cytotoxicity under Complement-Limiting Conditions (37 citations)

In his most recent research, the most cited papers focused on:

  • Antibody
  • Immune system
  • Internal medicine

Complement system, Antibody, Immunology, Monoclonal antibody and Cytotoxicity are his primary areas of study. His research in Complement system intersects with topics in Virology, Complement-dependent cytotoxicity, B cell, Cell biology and Cytotoxic T cell. As part of his studies on Antibody, he often connects relevant areas like Pharmacology.

His research in Immunology is mostly concerned with Antibody-dependent cell-mediated cytotoxicity. His Monoclonal antibody research focuses on subjects like Antigen, which are linked to Monoclonal and Cancer cell. His Cytotoxicity study which covers Classical complement pathway that intersects with Cellular immunity, Molecular biology and Effector.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mechanisms of killing by anti-CD20 monoclonal antibodies.

Martin J. Glennie;Ruth R. French;Mark S. Cragg;Ronald P. Taylor.
Molecular Immunology (2007)

576 Citations

Rituximab Infusion Promotes Rapid Complement Depletion and Acute CD20 Loss in Chronic Lymphocytic Leukemia

Adam D. Kennedy;Paul V. Beum;Michael D. Solga;David J. DiLillo.
Journal of Immunology (2004)

431 Citations

Complement is activated by IgG hexamers assembled at the cell surface.

Christoph A. Diebolder;Frank J. Beurskens;Rob N. de Jong;Roman I. Koning.
Science (2014)

394 Citations

Disease-associated loss of erythrocyte complement receptors (CR1, C3b receptors) in patients with systemic lupus erythematosus and other diseases involving autoantibodies and/or complement activation.

G D Ross;W J Yount;M J Walport;J B Winfield.
Journal of Immunology (1985)

385 Citations

Binding of submaximal C1q promotes complement-dependent cytotoxicity (CDC) of B cells opsonized with anti-CD20 mAbs ofatumumab (OFA) or rituximab (RTX): considerably higher levels of CDC are induced by OFA than by RTX.

Andrew W. Pawluczkowycz;Frank J. Beurskens;Paul V. Beum;Margaret A. Lindorfer.
Journal of Immunology (2009)

283 Citations

The Shaving Reaction: Rituximab/CD20 Complexes Are Removed from Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia Cells by THP-1 Monocytes

Paul V. Beum;Adam D. Kennedy;Michael E. Williams;Margaret A. Lindorfer.
Journal of Immunology (2006)

271 Citations

Physiological and pathological aspects of circulating immune complexes.

Jürg A. Schifferli;Ronald P. Taylor.
Kidney International (1989)

254 Citations

NK-cell activation and antibody-dependent cellular cytotoxicity induced by rituximab-coated target cells is inhibited by the C3b component of complement

Siao Yi Wang;Emilian Racila;Ronald P. Taylor;George J. Weiner.
Blood (2008)

209 Citations

An anti-C3b(i) mAb enhances complement activation, C3b(i) deposition and killing of CD20+ cells by Rituximab

Adam D. Kennedy;Michael D. Solga;Theodore A. Schuman;Amos W. Chi.
Blood (2003)

198 Citations

Immunotherapeutic mechanisms of anti-CD20 monoclonal antibodies.

Ronald P Taylor;Margaret A Lindorfer.
Current Opinion in Immunology (2008)

192 Citations

Best Scientists Citing Ronald P. Taylor

Paul W. H. I. Parren

Paul W. H. I. Parren

Leiden University Medical Center

Publications: 41

Vladimir R. Muzykantov

Vladimir R. Muzykantov

University of Pennsylvania

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Lubka T. Roumenina

Lubka T. Roumenina

Université Paris Cité

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John D. Lambris

John D. Lambris

University of Pennsylvania

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Mark S. Cragg

Mark S. Cragg

University of Southampton

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Christian Klein

Christian Klein

Roche (Switzerland)

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Martin J. Glennie

Martin J. Glennie

University of Southampton

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David M. Goldenberg

David M. Goldenberg

Pennsylvania State University

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Douglas B. Cines

Douglas B. Cines

University of Pennsylvania

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David S. Pisetsky

David S. Pisetsky

Duke University

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Véronique Frémeaux-Bacchi

Véronique Frémeaux-Bacchi

Inserm : Institut national de la santé et de la recherche médicale

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Jonathan R. Lindner

Jonathan R. Lindner

Oregon Health & Science University

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V. Michael Holers

V. Michael Holers

University of Colorado Denver

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John C. Byrd

John C. Byrd

University of Cincinnati

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Josée Golay

Josée Golay

Mario Negri Institute for Pharmacological Research

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Jan G. J. van de Winkel

Jan G. J. van de Winkel

Genmab (United States)

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Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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