World's Best Scientists 2026 revealed!

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Immunology

D-Index
79
Citations
22525
World Ranking
1688
National Ranking
831

Genetics

D-Index
78
Citations
21824
World Ranking
1702
National Ranking
783

Overview

Jeffrey C. Edberg is affiliated with the University of Alabama at Birmingham in the United States. Their research contributions span fields including Medicine and Biochemistry, Genetics and Molecular Biology, with significant focus on Genetics, Immunology, Rheumatology, Pharmacology, and Psychiatry and Mental Health.

The scientist's work addresses various topics, prominently including:

  • Immune Cell Function and Interaction
  • Musculoskeletal pain and rehabilitation
  • T-cell and B-cell Immunology
  • Genomics and Rare Diseases
  • Genetic Associations and Epidemiology
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Lymphoma Diagnosis and Treatment

Their recent publications reflect an emphasis on genetic and immunological aspects of disease, with notable papers such as:

  • Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis, 2022, Nature Genetics
  • Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes, 2021, Nature Genetics
  • Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • A state-based approach to genomics for rare disease and population screening, 2020, Genetics in Medicine
  • Nicotinamide Adenine Dinucleotide Biosynthetic Impairment and Urinary Metabolomic Alterations Observed in Hospitalized Adults With COVID-19-Related Acute Kidney Injury, 2021, Kidney International Reports

Frequent coauthors collaborating with Jeffrey C. Edberg include:

  • Robert P. Kimberly
  • S. Louis Bridges
  • Peter K. Gregersen
  • Angela M. Mickle
  • Cynthia Garvan

The scientist has regularly published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Nature Genetics
  • Genetics in Medicine
  • Brain Behavior & Immunity - Health

Jeffrey C. Edberg's work integrates genomics with clinical and immunological insights, contributing to an understanding of complex diseases such as rheumatoid arthritis, type 1 diabetes, rare diseases, and COVID-19-related complications.

Best Publications

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

    John B. Harley;John B. Harley;John B. Harley;Marta E. Alarcón-Riquelme;Lindsey A. Criswell;Chaim O. Jacob

  • A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

    Vesela Gateva;Johanna K. Sandling;Geoff Hom;Kimberly E. Taylor

  • A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease.

    Jianming Wu;Jeffrey C. Edberg;Patricia B. Redecha;Vipin Bansal

  • Novel single nucleotide polymorphisms in the distal IL-10 promoter affect IL-10 production and enhance the risk of systemic lupus erythematosus.

    Andrew W. Gibson;Jeffrey C. Edberg;Jianming Wu;Rudi G. J. Westendorp

  • Genome-Wide DNA Methylation Analysis of Systemic Lupus Erythematosus Reveals Persistent Hypomethylation of Interferon Genes and Compositional Changes to CD4+ T-cell Populations

    Devin M. Absher;Xinrui Li;Lindsay L. Waite;Andrew Gibson

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • IgA1-secreting cell lines from patients with IgA nephropathy produce aberrantly glycosylated IgA1

    Hitoshi Suzuki;Zina Moldoveanu;Stacy Hall;Rhubell Brown

  • Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

    B. Namjou;P. H. Kothari;J. A. Kelly;S. B. Glenn

  • Allelic polymorphisms of human Fc gamma receptor IIA and Fc gamma receptor IIIB. Independent mechanisms for differences in human phagocyte function.

    J E Salmon;J C Edberg;N L Brogle;R P Kimberly

  • Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

    Indra Adrianto;Feng Wen;Amanda Templeton;Graham B. Wiley

  • Fc gamma receptor III on human neutrophils. Allelic variants have functionally distinct capacities.

    J E Salmon;J C Edberg;R P Kimberly

  • End-stage renal disease in African Americans with lupus nephritis is associated with APOL1.

    Barry I. Freedman;Carl D. Langefeld;Kelly K. Andringa;Jennifer A. Croker

  • C-reactive protein binding to FcγRIIa on human monocytes and neutrophils is allele-specific

    Mary-Pat Stein;Jeffrey C. Edberg;Robert P. Kimberly;Erin K. Mangan

  • A Novel Polymorphic CAAT/Enhancer-Binding Protein β Element in the FasL Gene Promoter Alters Fas Ligand Expression: A Candidate Background Gene in African American Systemic Lupus Erythematosus Patients

    Jianming Wu;Christine Metz;Xiulong Xu;Riichiro Abe

  • Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.

    C C Robertson;Inshaw Jrj.;S Onengut-Gumuscu;Chen W-M.

  • A Promoter Haplotype of the Immunoreceptor Tyrosine-Based Inhibitory Motif-Bearing FcγRIIb Alters Receptor Expression and Associates with Autoimmunity. I. Regulatory FCGR2B Polymorphisms and Their Association with Systemic Lupus Erythematosus

    Kaihong Su;Jianming Wu;Jeffrey C. Edberg;Xiaoli Li

  • Single-nucleotide polymorphisms in the C-reactive protein (CRP) gene promoter that affect transcription factor binding, alter transcriptional activity, and associate with differences in baseline serum CRP level

    A. J. Szalai;A. J. Szalai;J. Wu;E. M. Lange;M. A. McCrory

  • The influence of genetic variation in the HLA-DRB1 and LTA-TNF regions on the response to treatment of early rheumatoid arthritis with methotrexate or etanercept.

    Lindsey A. Criswell;Raymond F. Lum;Kevin N. Turner;Blanche Woehl

  • Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility

    Jian Zhao;Hui Wu;Melanie Khosravi;Huijuan Cui

  • Expression Profile of FcγRIIb on Leukocytes and Its Dysregulation in Systemic Lupus Erythematosus

    Kaihong Su;Hengxuan Yang;Xinrui Li;Xiaoli Li

Frequent Co-Authors

Robert P. Kimberly
Robert P. Kimberly University of Alabama at Birmingham
John B. Harley
John B. Harley United States Department of Veterans Affairs
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
Judith A. James
Judith A. James Oklahoma Medical Research Foundation
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
Graciela S. Alarcón
Graciela S. Alarcón University of Alabama at Birmingham
John D. Reveille
John D. Reveille The University of Texas Health Science Center at Houston
Carl D. Langefeld
Carl D. Langefeld Wake Forest University
Michelle Petri
Michelle Petri Johns Hopkins University School of Medicine
Patrick M. Gaffney
Patrick M. Gaffney Oklahoma Medical Research Foundation

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