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Timothy B. Niewold

Timothy B. Niewold

D-Index & Metrics

Immunology

D-Index
77
Citations
19439
World Ranking
1838
National Ranking
901

Overview

Timothy B. Niewold is a researcher affiliated with New York University in the United States. Their work spans multiple fields within medicine, with a primary focus on immunology and rheumatology. The scientist has published extensively, contributing to over 110 studies in medicine and 32 specifically in immunology and microbiology. Their research interests delve deeply into systemic lupus erythematosus (SLE) and related immune system mechanisms.

The main topics of their research include systemic lupus erythematosus research, T-cell and B-cell immunology, monoclonal and polyclonal antibodies research, inflammatory myopathies and dermatomyositis, renal diseases and glomerulopathies, atherosclerosis and cardiovascular diseases, and inflammasome and immune disorders.

They have contributed papers to several publication venues frequently, including:

  • Translational Research
  • Journal of the American Society of Nephrology
  • The Journal of Rheumatology
  • Annals of the Rheumatic Diseases
  • Arthritis Research & Therapy

Recent published papers feature research on the role of immune signaling and disease mechanisms. These works include:

  • Type I interferon in the pathogenesis of systemic lupus erythematosus (2020), published in Current Opinion in Immunology
  • TLR7 and TLR8 Differentially Activate the IRF and NF-κB Pathways in Specific Cell Types to Promote Inflammation (2020), published in ImmunoHorizons
  • Clinical disease activity and flare in SLE: Current concepts and novel biomarkers (2021), published in Journal of Autoimmunity
  • COVID-19 in patients with systemic lupus erythematosus: lessons learned from the inflammatory disease (2020), published in Translational Research
  • Progressive Cellular Senescence Mediates Renal Dysfunction in Ischemic Nephropathy (2021), published in Journal of the American Society of Nephrology

The scientist collaborates frequently with several peers, including Ruth Fernandez-Ruiz, Jacqueline L Paredes, Simone Appenzeller, Vilija Oke, and Ashira Blazer. These frequent coauthors have contributed significantly to overlapping studies in related fields.

Subfields of study for this researcher include rheumatology, immunology, epidemiology, radiology, nuclear medicine and imaging, as well as pathology and forensic medicine. This interdisciplinary approach supports a comprehensive understanding of the mechanisms underlying autoimmune diseases and their systemic impacts.

Best Publications

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus

    Scott A. Jenks;Kevin S. Cashman;Esther Zumaquero;Urko M. Marigorta

  • High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus.

    T B Niewold;J Hua;T J A Lehman;J B Harley

  • MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease.

    Pierre-Antoine Juge;Joyce S Lee;Esther Ebstein;Hiroshi Furukawa

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

    B. Namjou;P. H. Kothari;J. A. Kelly;S. B. Glenn

  • Type I interferon in rheumatic diseases

    Theresa L. Wampler Muskardin;Timothy B. Niewold

  • Cutting Edge: Autoimmune Disease Risk Variant of STAT4 Confers Increased Sensitivity to IFN-α in Lupus Patients In Vivo

    Silvia N. Kariuki;Kyriakos A. Kirou;Emma J. MacDermott;Lilliana Barillas-Arias

  • Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients

    Timothy B. Niewold;Jennifer A. Kelly;Marie H. Flesch;Luis R. Espinoza

  • Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus

    Lauren L Ritterhouse;Sherry R Crowe;Timothy B Niewold;Diane L Kamen

  • The Unexplained Female Predominance of Systemic Lupus Erythematosus: Clues from Genetic and Cytokine Studies

    Corinna E. Weckerle;Timothy B. Niewold

  • Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

    Indra Adrianto;Feng Wen;Amanda Templeton;Graham B. Wiley

  • End-stage renal disease in African Americans with lupus nephritis is associated with APOL1.

    Barry I. Freedman;Carl D. Langefeld;Kelly K. Andringa;Jennifer A. Croker

  • Network analysis of associations between serum interferon‐α activity, autoantibodies, and clinical features in systemic lupus erythematosus

    Corinna E. Weckerle;Beverly S. Franek;Jennifer A. Kelly;Marissa Kumabe

  • Immunogenetics of systemic lupus erythematosus: A comprehensive review.

    Yogita Ghodke-Puranik;Timothy B. Niewold

  • Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification.

    Melissa E Munroe;Rufei Lu;Yan D Zhao;Dustin A Fife

  • Type I interferon in the pathogenesis of systemic lupus erythematosus.

    Mariana Postal;Jessica F Vivaldo;Ruth Fernandez-Ruiz;Jacqueline L Paredes

  • Systemic lupus erythematosus arising during interferon-alpha therapy for cryoglobulinemic vasculitis associated with hepatitis C.

    Timothy B. Niewold;William I. Swedler

  • Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility

    Jian Zhao;Hui Wu;Melanie Khosravi;Huijuan Cui

  • High levels of circulating interferons type I, type II and type III associate with distinct clinical features of active systemic lupus erythematosus

    Vilija Oke;Iva Gunnarsson;Jessica Dorschner;Susanna Eketjäll

  • Anti-CCP antibody testing as a diagnostic and prognostic tool in rheumatoid arthritis.

    T.B. Niewold;M.J. Harrison;S.A. Paget

  • Interferon alpha as a primary pathogenic factor in human lupus.

    Timothy B. Niewold

Frequent Co-Authors

Judith A. James
Judith A. James Oklahoma Medical Research Foundation
John B. Harley
John B. Harley United States Department of Veterans Affairs
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
R. Hal Scofield
R. Hal Scofield University of Oklahoma Health Sciences Center
Jennifer A. Kelly
Jennifer A. Kelly Oklahoma Medical Research Foundation
Patrick M. Gaffney
Patrick M. Gaffney Oklahoma Medical Research Foundation
Carl D. Langefeld
Carl D. Langefeld Wake Forest University
Robert P. Kimberly
Robert P. Kimberly University of Alabama at Birmingham
Gary S. Gilkeson
Gary S. Gilkeson Medical University of South Carolina

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