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Lars Rönnblom

Lars Rönnblom

D-Index & Metrics

Immunology

D-Index
85
Citations
26919
World Ranking
1314
National Ranking
25

Medicine

D-Index
85
Citations
26946
World Ranking
14594
National Ranking
272

Overview

Lars Rönnblom is affiliated with Uppsala University in Sweden and conducts research primarily in the fields of Medicine and Immunology and Microbiology. Their work covers several subfields, notably Immunology, Rheumatology, Genetics, Physiology, and Radiology, Nuclear Medicine and Imaging.

The scientist's research topics include:

  • Systemic Lupus Erythematosus Research
  • T-cell and B-cell Immunology
  • Monoclonal and Polyclonal Antibodies Research
  • Salivary Gland Disorders and Functions
  • Cytokine Signaling Pathways and Interactions
  • Immune Cell Function and Interaction
  • Interferon and Immune Responses

Lars Rönnblom has published extensively, with frequent contributions to the following venues:

  • Annals of the Rheumatic Diseases
  • Poster presentations
  • RMD Open
  • Lara D. Veeken
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent publications include:

  • Actionable druggable genome-wide Mendelian randomization identifies repurposing opportunities for COVID-19, 2021, Nature Medicine
  • Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells, 2022, Nature Communications
  • Molecular pathways in patients with systemic lupus erythematosus revealed by gene-centred DNA sequencing, 2020, Annals of the Rheumatic Diseases
  • NETs decorated with bioactive IL-33 infiltrate inflamed tissues and induce IFN-α production in patients with SLE, 2021, JCI Insight
  • Four Systemic Lupus Erythematosus Subgroups, Defined by Autoantibodies Status, Differ Regarding HLA-DRB1 Genotype Associations and Immunological and Clinical Manifestations, 2021, ACR Open Rheumatology

The scientist frequently collaborates with a group of co-authors including Dag Leonard, Anders Bengtsson, Maija-Leena Eloranta, Andreas Jönsen, and Christopher Sjöwall, with co-authorship counts ranging from 34 to 38 publications each.

Best Publications

  • Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX.

    Geoffrey Hom;Robert R. Graham;Barmak Modrek;Kimberly E. Taylor

  • Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus

    James Bentham;David L. Morris;Deborah S. Cunninghame Graham;Christopher L. Pinder

  • A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

    Vesela Gateva;Johanna K. Sandling;Geoff Hom;Kimberly E. Taylor

  • Polymorphisms in the Tyrosine Kinase 2 and Interferon Regulatory Factor 5 Genes Are Associated with Systemic Lupus Erythematosus

    Snaevar Sigurdsson;Gunnel Nordmark;Harald H.H. Göring;Katarina Lindroos

  • Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.

    Tanja Lövgren;Maija-Leena Eloranta;Ullvi Båve;Gunnar V. Alm

  • Activation of type I interferon system in systemic lupus erythematosus correlates with disease activity but not with antiretroviral antibodies

    Anders Bengtsson;Gunnar Sturfelt;Lennart Truedsson;J Blomberg

  • Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus.

    Robert R. Graham;Chieko Kyogoku;Snaevar Sigurdsson;Irina A. Vlasova

  • Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome.

    Christopher J. Lessard;Christopher J. Lessard;He Li;He Li;Indra Adrianto;John A. Ice

  • Autoimmunity after Alpha-Interferon Therapy for Malignant Carcinoid Tumors

    Lars E. Rönnblom;Gunnar V. Alm;Kjell E. Öberg

  • Activation of the type I interferon system in primary Sjogren's syndrome : a possible etiopathogenic mechanism

    Ullvi Båve;Gunnel Nordmark;Tanja Lövgren;Johan Rönnelid

  • Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG.

    Ullvi Båve;Mattias Magnusson;Maija-Leena Eloranta;Anders Perers

  • Possible induction of systemic lupus erythematosus by interferon‐α treatment in a patient with a malignant carcinoid tumour

    L. E. Rönnblom;G. V. Alm;K. E. Öberg

  • Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia

    Jessica Nordlund;Christofer L Bäcklin;Per Wahlberg;Stephan Busche

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • The type I interferon system in systemic lupus erythematosus.

    Lars Rönnblom;Maija-Leena Eloranta;Gunnar V. Alm

  • Anti-double-stranded DNA antibodies and immunostimulatory plasmid DNA in combination mimic the endogenous IFN-alpha inducer in systemic lupus erythematosus.

    Helena Vallin;Anders Perers;Gunnar V. Alm;Lars Rönnblom

  • Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with systemic lupus erythematosus.

    Deborah S. Cunninghame Graham;David L. Morris;Tushar R. Bhangale;Lindsey A. Criswell

  • The innate immune system in SLE: type I interferons and dendritic cells

    Lars Rönnblom;V. Pascual

  • A Pivotal Role for the Natural Interferon α–producing Cells (Plasmacytoid Dendritic Cells) in the Pathogenesis of Lupus

    Lars Rönnblom;Gunnar V. Alm

  • Interferon pathway in SLE: one key to unlocking the mystery of the disease

    Lars Rönnblom;Dag Leonard

  • Patients with systemic lupus erythematosus have reduced numbers of circulating natural interferon-alpha-producing cells

    B. Cederblad;S. Blomberg;H. Vallin;A. Perers

Frequent Co-Authors

Gunnar V. Alm
Gunnar V. Alm Swedish University of Agricultural Sciences
Ann-Christine Syvänen
Ann-Christine Syvänen Uppsala University
Anders A. Bengtsson
Anders A. Bengtsson Lund University
Maija-Leena Eloranta
Maija-Leena Eloranta Uppsala University
Elisabet Svenungsson
Elisabet Svenungsson Karolinska University Hospital
Andreas Jönsen
Andreas Jönsen Lund University
Roland Jonsson
Roland Jonsson University of Bergen
Marie Wahren-Herlenius
Marie Wahren-Herlenius Karolinska Institute
Gunnar Sturfelt
Gunnar Sturfelt Lund University
Iva Gunnarsson
Iva Gunnarsson Karolinska University Hospital

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