Maija-Leena Eloranta

Best Publications

• Polymorphisms in the Tyrosine Kinase 2 and Interferon Regulatory Factor 5 Genes Are Associated with Systemic Lupus Erythematosus

  Snaevar Sigurdsson;Gunnel Nordmark;Harald H.H. Göring;Katarina Lindroos

  741
  Citations

• Induction of interferon-alpha production in plasmacytoid dendritic cells by immune complexes containing nucleic acid released by necrotic or late apoptotic cells and lupus IgG.

  Tanja Lövgren;Maija-Leena Eloranta;Ullvi Båve;Gunnar V. Alm

  663
  Citations

• Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome.

  Christopher J. Lessard;Christopher J. Lessard;He Li;He Li;Indra Adrianto;John A. Ice

  571
  Citations

• Activation of the type I interferon system in primary Sjogren's syndrome : a possible etiopathogenic mechanism

  Ullvi Båve;Gunnel Nordmark;Tanja Lövgren;Johan Rönnelid

  464
  Citations

• Fc gamma RIIa is expressed on natural IFN-alpha-producing cells (plasmacytoid dendritic cells) and is required for the IFN-alpha production induced by apoptotic cells combined with lupus IgG.

  Ullvi Båve;Mattias Magnusson;Maija-Leena Eloranta;Anders Perers

  448
  Citations

• The type I interferon system in systemic lupus erythematosus.

  Lars Rönnblom;Maija-Leena Eloranta;Gunnar V. Alm

  396
  Citations

• Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway

  Alexander Espinosa;Valerie Dardalhon;Susanna Brauner;Aurelie Ambrosi

  351
  Citations

• The interferon signature in autoimmune diseases.

  Lars Rönnblom;Maija-Leena Eloranta

  326
  Citations

• A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5

  Snaevar Sigurdsson;Gunnel Nordmark;Sophie Garnier;Elin Grundberg

  305
  Citations

• The type I interferon system in the development of lupus.

  Lars Rönnblom;Gunnar V. Alm;Maija-Leena Eloranta

  281
  Citations

• Presence of cutaneous interferon-a producing cells in patients with systemic lupus erythematosus

  S Blomberg;M L Eloranta;B Cederblad;K Nordlind

  281
  Citations

• Comprehensive evaluation of the genetic variants of interferon regulatory factor 5 (IRF5) reveals a novel 5 bp length polymorphism as strong risk factor for systemic lupus erythematosus

  Snaevar Sigurdsson;Harald H H Göring;Gudlaug Kristjansdottir;Lili Milani

  269
  Citations

• Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration

  Y Akwa;D E Hassett;M L Eloranta;K Sandberg

  261
  Citations

• Interferon-β is required for interferon-α production in mouse fibroblasts

  Lena Erlandsson;Ralf Blumenthal;Maija-Leena Eloranta;Holger Engel

  254
  Citations

• A possible mechanism for endogenous activation of the type I interferon system in myositis patients with anti–Jo-1 or anti–Ro 52/anti–Ro 60 autoantibodies

  Maija-Leena Eloranta;Sevim Barbasso Helmers;Sevim Barbasso Helmers;Ann-Kristin Ulfgren;Ann-Kristin Ulfgren;Lars Rönnblom

  249
  Citations

• C1q inhibits immune complex-induced interferon-alpha production in plasmacytoid dendritic cells: a novel link between C1q deficiency and systemic lupus erythematosus pathogenesis.

  Christian Lood;Birgitta Gullstrand;Lennart Truedsson;Anders I. Olin

  227
  Citations

• Induction of interferon-alpha by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjögren's syndrome autoantigen-associated RNA.

  Tanja Lövgren;Maija-Leena Eloranta;Berthold Kastner;Marie Wahren-Herlenius

  226
  Citations

• Expression of the markers BDCA-2 and BDCA-4 and production of interferon-alpha by plasmacytoid dendritic cells in systemic lupus erythematosus.

  Stina Blomberg;Maija-Leena Eloranta;Mattias Magnusson;Gunnar V. Alm

  221
  Citations

• Genome-wide DNA methylation analysis in multiple tissues in primary Sjögren's syndrome reveals regulatory effects at interferon-induced genes

  Juliana Imgenberg-Kreuz;Johanna K Sandling;Jonas Carlsson Almlöf;Jessica Nordlund

  218
  Citations

• Recruitment and Activation of Natural Killer (Nk) Cells in Vivo Determined by the Target Cell Phenotype: An Adaptive Component of Nk Cell–Mediated Responses

  Rickard Glas;Lars Franksson;Clas Une;Maija-Leena Eloranta

  215
  Citations