World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
119
Citations
55279
World Ranking
390
National Ranking
199

Medicine

D-Index
125
Citations
60847
World Ranking
3087
National Ranking
1704

Overview

Carl D. Langefeld is affiliated with Wake Forest University in the United States. Their research spans multiple fields, primarily focusing on medicine and biochemistry, genetics, and molecular biology.

The scientist's work extensively covers the following subfields:

  • Molecular Biology
  • Genetics
  • Immunology
  • Neurology
  • Rheumatology

The main topics of their research include:

  • Intracerebral and Subarachnoid Hemorrhage Research
  • Genetic Associations and Epidemiology
  • Systemic Lupus Erythematosus Research
  • Acute Ischemic Stroke Management
  • Epigenetics and DNA Methylation
  • Atherosclerosis and Cardiovascular Diseases
  • Single-cell and spatial transcriptomics

Frequent co-authors with whom Carl D. Langefeld has collaborated include:

  • Daniel Woo
  • Mary E. Comeau
  • Timothy D. Howard
  • Barry I. Freedman
  • Christopher D. Anderson

The scientist has published in several venues, most frequently in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • UNC Libraries
  • Stroke
  • Diabetes
  • Neurology

Selected recent publications by Carl D. Langefeld include:

  • The trans-ancestral genomic architecture of glycemic traits, Nature Genetics, 2021
  • A practical solution to pseudoreplication bias in single-cell studies, Nature Communications, 2021
  • Complement genes contribute sex-biased vulnerability in diverse disorders, Nature, 2020
  • Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification, Nature Genetics, 2023
  • Risk Factors Associated With Mortality and Neurologic Disability After Intracerebral Hemorrhage in a Racially and Ethnically Diverse Cohort, JAMA Network Open, 2022

Best Publications

  • Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

    Georg B. Ehret;Georg B. Ehret;Georg B. Ehret;Patricia B. Munroe;Kenneth M. Rice;Murielle Bochud

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Association of trypanolytic ApoL1 variants with kidney disease in African Americans.

    Giulio Genovese;Giulio Genovese;David J. Friedman;Michael D. Ross;Laurence Lecordier

  • A genome-wide association search for type 2 diabetes genes in African Americans.

    N D Palmer;C W McDonough;P J Hicks;B H Roh

  • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

    John B. Harley;John B. Harley;John B. Harley;Marta E. Alarcón-Riquelme;Lindsey A. Criswell;Chaim O. Jacob

  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Mary F. Feitosa;Aldi T. Kraja;Daniel I. Chasman;Yun J. Sung

  • The trans-ancestral genomic architecture of glycemic traits

    Ji Chen;Ji Chen;Cassandra N. Spracklen;Cassandra N. Spracklen;Gaëlle Marenne;Gaëlle Marenne;Arushi Varshney

  • Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.

    Chieko Kyogoku;Carl D. Langefeld;Ward A. Ortmann;Annette Lee

  • Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study

    Philip C Haycock;Stephen Burgess;Aayah Nounu

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

    Anne Hinks;Anne Hinks;Joanna E. Cobb;Joanna E. Cobb;Miranda C. Marion;Sampath Prahalad

  • Integrated Omics: Tools, Advances, and Future Approaches

    Biswapriya B Misra;Carl D Langefeld;Michael Olivier;Laura A Cox;Laura A Cox

  • Genome-wide genotyping in Parkinson's disease and neurologically normal controls: first stage analysis and public release of data

    Hon-Chung Fung;Hon-Chung Fung;Hon-Chung Fung;Sonja Scholz;Mar Matarin;Javier Simón-Sánchez;Javier Simón-Sánchez

  • Insulin Sensitivity, Insulin Secretion, and Abdominal Fat: The Insulin Resistance Atherosclerosis Study (IRAS) Family Study

    Lynne E. Wagenknecht;Carl D. Langefeld;Ann L. Scherzinger;Jill M. Norris

  • Adiponectin as a novel determinant of bone mineral density and visceral fat

    Lenchik L;Register Tc;Hsu Fc;Lohman K

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

    B. Namjou;P. H. Kothari;J. A. Kelly;S. B. Glenn

  • Genetic susceptibility to SLE: new insights from fine mapping and genome-wide association studies.

    Isaac T. W. Harley;Kenneth M. Kaufman;Kenneth M. Kaufman;Carl D. Langefeld;John B. Harley;John B. Harley

  • Genomewide Screen and Identification of Gene-Gene Interactions for Asthma-Susceptibility Loci in Three U.S. Populations: Collaborative Study on the Genetics of Asthma

    Jianfeng Xu;Deborah A. Meyers;Carole Ober;Malcolm N. Blumenthal

  • Association of Trypanolytic ApoL1 Variants with Kidney Disease in

    Giulio Genovese;David J. Friedman;Michael D. Ross

Frequent Co-Authors

Donald W. Bowden
Donald W. Bowden Wake Forest University
Barry I. Freedman
Barry I. Freedman Wake Forest University
John B. Harley
John B. Harley United States Department of Veterans Affairs
Lynne E. Wagenknecht
Lynne E. Wagenknecht Wake Forest University
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
Nicholette D. Palmer
Nicholette D. Palmer Wake Forest University
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
Judith A. James
Judith A. James Oklahoma Medical Research Foundation
Patrick M. Gaffney
Patrick M. Gaffney Oklahoma Medical Research Foundation
Stephen S. Rich
Stephen S. Rich University of Virginia

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Genetics in the USA opens doors to a range of healthcare careers and online degrees. Many students interested in genetics may also consider roles like medical billing, coding, nursing, or healthcare administration. These fields offer pathways that balance strong job demand, flexible study options, and various entry levels.

For those drawn to the administrative side, a medical billing and coding certification cost can be surprisingly affordable. These certifications can be completed online and may lead to fast-growing positions in healthcare settings.

If you are interested in direct patient care, there are what nursing programs are easy to get into, helping students quickly begin their nursing careers with less restrictive admissions requirements.

For those looking to manage healthcare services, a degree in healthcare administration can be completed through accelerated online programs. This is a great choice for those wanting leadership roles. You can also explore options with a health administration degree online designed for flexibility and affordability.

Combining genetics with these related fields expands your career options and helps you find the best fit for your interests and goals in the evolving healthcare industry.

Best Scientists Citing Carl D. Langefeld

Trending Scientists