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Medicine

D-Index
116
Citations
54463
World Ranking
4327
National Ranking
2361

Overview

Barry I. Freedman is affiliated with Wake Forest University in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with extensive work in subfields such as Genetics, Nephrology, Molecular Biology, Cardiology and Cardiovascular Medicine, and Physiology.

The scientist's work focuses on specific topics within these disciplines, including Genetic Associations and Epidemiology, Renal Diseases and Glomerulopathies, Chronic Kidney Disease and Diabetes, Dialysis and Renal Disease Management, Renal Transplantation Outcomes and Treatments, Genomics and Rare Diseases, and Chronic Lymphocytic Leukemia Research.

Freedman's recent publications cover a range of high-impact studies, with titles such as:

  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes (2020, Nature)
  • Genetic diversity fuels gene discovery for tobacco and alcohol use (2022, Nature)
  • Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale (2020, Nature Genetics)
  • Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification (2023, Nature Genetics)
  • A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies (2022, Nature Methods)

They have frequently collaborated with co-authors in the field, notably Donald W. Bowden, Joshua C. Bis, Xiuqing Guo, John Blangero, and Donna K. Arnett. These collaborations reflect a sustained engagement with experts in genetics and related biomedical research.

Barry I. Freedman's research has been published extensively in venues including:

  • UNC Libraries
  • Journal of the American Society of Nephrology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Kidney International

Best Publications

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Association of trypanolytic ApoL1 variants with kidney disease in African Americans.

    Giulio Genovese;Giulio Genovese;David J. Friedman;Michael D. Ross;Laurence Lecordier

  • A genome-wide association search for type 2 diabetes genes in African Americans.

    N D Palmer;C W McDonough;P J Hicks;B H Roh

  • The Influence of CCL3L1 Gene-Containing Segmental Duplications on HIV-1/AIDS Susceptibility

    Enrique Gonzalez;Hemant Kulkarni;Hector Bolivar;Andrea Mangano

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Christian Fuchsberger;Jason A. Flannick;Jason A. Flannick;Tanya M. Teslovich;Anubha Mahajan

  • Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

    Mary F. Feitosa;Aldi T. Kraja;Daniel I. Chasman;Yun J. Sung

  • MYH9 is a major-effect risk gene for focal segmental glomerulosclerosis

    Jeffrey B Kopp;Michael W Smith;George W Nelson;Randall C Johnson

  • MYH9 is associated with nondiabetic end-stage renal disease in African Americans

    W H Linda Kao;Michael J Klag;Lucy A Meoni;David Reich;David Reich

  • APOL1 Risk Variants, Race, and Progression of Chronic Kidney Disease

    Afshin Parsa;W. H Linda Kao;Dawei Xie;Brad C. Astor

  • Inherited causes of clonal haematopoiesis in 97,691 whole genomes.

    Alexander G Bick;Joshua S Weinstock;Satish K Nandakumar;Satish K Nandakumar;Charles P Fulco;Charles P Fulco

  • Randomized Trial of an Inhibitor of Formation of Advanced Glycation End Products in Diabetic Nephropathy

    W. Kline Bolton;Daniel C. Cattran;Mark E. Williams;Sharon G. Adler

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • Worldwide Ethnic Distribution of the G Protein β3 Subunit 825T Allele and Its Association with Obesity in Caucasian, Chinese, and Black African Individuals

    Winfried Siffert;Peter Forster;Karl-Heinz Jöckel;David A. Mvere

  • Diabetic Microvascular Disease: An Endocrine Society Scientific Statement.

    Eugene J Barrett;Zhenqi Liu;Mogher Khamaisi;George L King

  • Adiponectin as a novel determinant of bone mineral density and visceral fat

    Lenchik L;Register Tc;Hsu Fc;Lohman K

  • Comparison of glycated albumin and hemoglobin A1c levels in diabetic subjects on hemodialysis

    T.P. Peacock;Z.K. Shihabi;A.J. Bleyer;E.L. Dolbare

  • Genetic and environmental factors associated with type 2 diabetes and diabetic vascular complications.

    Mariana Murea;Lijun Ma;Barry I Freedman

  • Effects of Intensive BP Control in CKD

    Alfred K. Cheung;Mahboob Rahman;Mahboob Rahman;David M. Reboussin;Timothy E. Craven

  • Association of Trypanolytic ApoL1 Variants with Kidney Disease in

    Giulio Genovese;David J. Friedman;Michael D. Ross

  • The genetic architecture of type 2 diabetes

    Christian Fuchsberger;Jason Flannick;Tanya M. Teslovich;Anubha Mahajan

Frequent Co-Authors

Donald W. Bowden
Donald W. Bowden Wake Forest University
Carl D. Langefeld
Carl D. Langefeld Wake Forest University
Nicholette D. Palmer
Nicholette D. Palmer Wake Forest University
Stephen S. Rich
Stephen S. Rich University of Virginia
J. Jeffrey Carr
J. Jeffrey Carr Vanderbilt University Medical Center
Lynne E. Wagenknecht
Lynne E. Wagenknecht Wake Forest University
Judith A. James
Judith A. James Oklahoma Medical Research Foundation
John B. Harley
John B. Harley United States Department of Veterans Affairs
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada

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