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Immunology

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92
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32089
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1003
National Ranking
545

Medicine

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Overview

Gary S. Gilkeson is affiliated with the Medical University of South Carolina in the United States and has contributed extensively to research in medicine, immunology, and molecular biology. Their scholarly work spans multiple interconnected fields with a strong focus on systemic autoimmune diseases and immune system function.

The main fields of study covered by Gilkeson's research include Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology. Within these, key subfields of study are Immunology, Genetics, Rheumatology, Oncology, and Molecular Biology.

Research topics prominently featured in their body of work include Systemic Lupus Erythematosus Research, T-cell and B-cell Immunology, Systemic Sclerosis and Related Diseases, Mesenchymal stem cell research, Gut microbiota and health, Cytokine Signaling Pathways and Interactions, and Immune Cell Function and Interaction.

Frequent publication venues for Gilkeson's research include:

  • Annals of the Rheumatic Diseases
  • Arthritis & Rheumatology
  • Journal of Autoimmunity
  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)

Notable recent papers authored or coauthored by Gilkeson are:

  • "Gut microbiota differently contributes to intestinal immune phenotype and systemic autoimmune progression in female and male lupus-prone mice," 2020, Journal of Autoimmunity
  • "Safety, immunological effects and clinical response in a phase I trial of umbilical cord mesenchymal stromal cells in patients with treatment refractory SLE," 2022, Lupus Science & Medicine
  • "Human SLE variant NCF1-R90H promotes kidney damage and murine lupus through enhanced Tfh2 responses induced by defective efferocytosis of macrophages," 2021, Annals of the Rheumatic Diseases
  • "Camptothecin and Topotecan, Inhibitors of Transcription Factor Fli-1 and Topoisomerase, Markedly Ameliorate Lupus Nephritis in (NZB × NZW)F1 Mice and Reduce the Production of Inflammatory Mediators in Human Renal Cells," 2021, Arthritis & Rheumatology
  • "Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus," 2022, Annals of the Rheumatic Diseases

Gilkeson has collaborated frequently with several researchers, including:

  • Diane L. Kamen
  • Betty P. Tsao
  • Jim C. Oates
  • Melissa Cunningham
  • Quan-Zhen Li

Best Publications

  • Human polymorphism at microRNAs and microRNA target sites.

    Liuqing Yang;Chunru Lin;Chunyu Jin;Joy C. Yang

  • Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

    John B. Harley;John B. Harley;John B. Harley;Marta E. Alarcón-Riquelme;Lindsey A. Criswell;Chaim O. Jacob

  • Mycophenolate mofetil or intravenous cyclophosphamide for lupus nephritis

    Ellen M. Ginzler;Mary Anne Dooley;Cynthia Aranow;Mimi Y. Kim

  • Mycophenolate Mofetil versus Cyclophosphamide for Induction Treatment of Lupus Nephritis

    Gerald B. Appel;Gabriel Contreras;Mary Anne Dooley;Ellen M. Ginzler

  • A pathogenetic role for TNFα in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency

    Gregory A Taylor;Ester Carballo;David M Lee;Wi S Lai

  • The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally administered NG-monomethyl-L-arginine.

    J B Weinberg;D L Granger;D S Pisetsky;M F Seldin

  • Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus

    Lingyun Sun;Dandan Wang;Jun Liang;Huayong Zhang

  • Vitamin D deficiency in systemic lupus erythematosus.

    Diane L. Kamen;Glinda S. Cooper;Henda Bouali;Stephanie R. Shaftman

  • Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study

    Jun Liang;Huayong Zhang;Bingzhu Hua;Hong Wang

  • Genetic reconstitution of systemic lupus erythematosus immunopathology with polycongenic murine strains

    Laurence Morel;Byron P. Croker;Kim R. Blenman;Chandra Mohan

  • Lack of a Functional Alternative Complement Pathway Ameliorates Ischemic Acute Renal Failure in Mice

    Joshua M. Thurman;Danica Ljubanovic;Charles L. Edelstein;Gary S. Gilkeson

  • Transancestral mapping and genetic load in systemic lupus erythematosus

    Carl D. Langefeld;Hannah C. Ainsworth;Deborah S. Cunninghame Graham;Jennifer A. Kelly

  • A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus.

    Swapan K. Nath;Shizhong Han;Xana Kim-Howard;Jennifer A. Kelly

  • Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort

    B. Namjou;P. H. Kothari;J. A. Kelly;S. B. Glenn

  • Estrogen receptors in immunity and autoimmunity.

    Melissa Cunningham;Gary Gilkeson

  • Hormonal, environmental, and infectious risk factors for developing systemic lupus erythematosus.

    Glinda S. Cooper;Mary Anne Dooley;Edward L. Treadwell;E. William St. Clair

  • Allogeneic mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus: 4 years of experience.

    Dandan Wang;Huayong Zhang;Jun Liang;Xia Li

  • A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

    Keri L. Monda;Keri L. Monda;Gary K. Chen;Kira C. Taylor;Kira C. Taylor;Cameron Palmer;Cameron Palmer

  • Suppression of Humoral Immunity in Mice following Exposure to Perfluorooctane Sulfonate

    Margie M. Peden-Adams;Jennifer M. Keller;Jackie G. EuDaly;Jennifer Berger

  • Modulation of Renal Disease in MRL/lpr Mice Genetically Deficient in the Alternative Complement Pathway Factor B

    Hiroshi Watanabe;Gérard Garnier;Antonella Circolo;Rick A. Wetsel

Frequent Co-Authors

John B. Harley
John B. Harley United States Department of Veterans Affairs
Judith A. James
Judith A. James Oklahoma Medical Research Foundation
Kenneth M. Kaufman
Kenneth M. Kaufman Cincinnati Children's Hospital Medical Center
Marta E. Alarcón-Riquelme
Marta E. Alarcón-Riquelme University of Granada
Jennifer A. Kelly
Jennifer A. Kelly Oklahoma Medical Research Foundation
R. Hal Scofield
R. Hal Scofield University of Oklahoma Health Sciences Center
Patrick M. Gaffney
Patrick M. Gaffney Oklahoma Medical Research Foundation
Robert P. Kimberly
Robert P. Kimberly University of Alabama at Birmingham
Timothy J. Vyse
Timothy J. Vyse King's College London
Carl D. Langefeld
Carl D. Langefeld Wake Forest University

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