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Immunology

D-Index
73
Citations
28245
World Ranking
2088
National Ranking
183

Overview

Mark S. Cragg is affiliated with the University of Southampton in the United Kingdom and has contributed extensively to biomedical research, focusing primarily on medicine and immunology. Their publication record spans multiple subfields, including immunology, radiology, oncology, molecular biology, and genetics.

The main fields of study for this researcher are:

  • Medicine
  • Immunology and Microbiology

Subfields where Mark S. Cragg has published include:

  • Immunology
  • Radiology, Nuclear Medicine and Imaging
  • Oncology
  • Molecular Biology
  • Genetics

The research topics frequently covered by Mark S. Cragg encompass:

  • Monoclonal and Polyclonal Antibodies Research
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • CAR-T cell therapy research
  • Chronic Lymphocytic Leukemia Research
  • Lymphoma Diagnosis and Treatment

Recent papers authored or co-authored by Mark S. Cragg include:

  • Reducing affinity as a strategy to boost immunomodulatory antibody agonism, 2023, Nature
  • Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology, 2021, Cell Reports
  • Fc-Engineering for Modulated Effector Functions-Improving Antibodies for Cancer Treatment, 2020, Antibodies
  • Signaling through the Inhibitory Fc Receptor FcγRIIB Induces CD8+ T Cell Apoptosis to Limit T Cell Immunity, 2020, Immunity
  • Genetic and evolutionary patterns of treatment resistance in relapsed B-cell lymphoma, 2020, Blood Advances

Mark S. Cragg frequently collaborates with several researchers, including:

  • Stephen A. Beers
  • Björn Frendéus
  • Robert Oldham
  • H. T. Claude Chan
  • Tatyana Inzhelevskaya

The primary venues for their publications include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Blood
  • Blood Advances
  • Frontiers in Immunology
  • Journal for ImmunoTherapy of Cancer

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas

    Jessica L Teeling;Ruth R French;Mark S Cragg;Jeroen van den Brakel

  • Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain

    Katharine Askew;Kaizhen Li;Adrian Olmos-Alonso;Fernando Garcia-Moreno

  • Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts

    Mark S Cragg;Suzanne M Morgan;H T Claude Chan;B Paul Morgan

  • Mechanisms of killing by anti-CD20 monoclonal antibodies.

    Martin J. Glennie;Ruth R. French;Mark S. Cragg;Ronald P. Taylor

  • Antibody specificity controls in vivo effector mechanisms of anti-CD20 reagents.

    Mark S. Cragg;Martin J. Glennie

  • The biology of CD20 and its potential as a target for mAb therapy.

    Mark S. Cragg;Claire A. Walshe;Andrey O. Ivanov;Martin J. Glennie

  • Antigenic modulation limits the efficacy of anti-CD20 antibodies: implications for antibody selection

    Stephen A. Beers;Ruth R. French;H. T. Claude Chan;Sean H. Lim

  • Gefitinib-Induced Killing of NSCLC Cell Lines Expressing Mutant EGFR Requires BIM and Can Be Enhanced by BH3 Mimetics

    Mark S Cragg;Junya Kuroda;Hamsa Puthalakath;David C. S Huang

  • Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic

    Junya Kuroda;Hamsa Puthalakath;Mark S. Cragg;Priscilla N. Kelly;Priscilla N. Kelly

  • Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies

    Waleed Alduaij;Andrei Ivanov;Jamie Honeychurch;Eleanor J Cheadle

  • Anti-CD20 monoclonal antibodies: historical and future perspectives

    Sean H. Lim;Stephen A. Beers;Ruth R. French;Peter W.M. Johnson

  • Fc gamma receptor IIb on target B cells promotes rituximab internalization and reduces clinical efficacy

    Sean H Lim;Andrew T Vaughan;Margaret Ashton-Key;Emily L Williams

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • CD20-induced lymphoma cell death is independent of both caspases and its redistribution into triton X-100 insoluble membrane rafts

    H T Claude Chan;David Hughes;Ruth R French;Alison L Tutt

  • CD20 as a target for therapeutic type I and II monoclonal antibodies.

    Stephen A. Beers;Claude H.T. Chan;Ruth R. French;Mark S. Cragg

  • Replicative senescence dictates the emergence of disease-associated microglia and contributes to Aβ pathology.

    Yanling Hu;Gemma L. Fryatt;Mohammadmersad Ghorbani;Juliane Obst

  • Interaction with FcγRIIB Is Critical for the Agonistic Activity of Anti-CD40 Monoclonal Antibody

    Ann L. White;H. T. Claude Chan;Ali Roghanian;Ruth R. French

  • Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics

    Mark S. Cragg;Claire Harris;Claire Harris;Andreas Strasser;Clare L. Scott;Clare L. Scott

  • Treatment of B-RAF mutant human tumor cells with a MEK inhibitor requires Bim and is enhanced by a BH3 mimetic

    Mark S. Cragg;Elisa S. Jansen;Michele Cook;Claire Harris

Frequent Co-Authors

Martin J. Glennie
Martin J. Glennie University of Southampton
Peter Johnson
Peter Johnson University of Southampton
Graham Packham
Graham Packham University of Southampton
Aymen Al-Shamkhani
Aymen Al-Shamkhani University of Southampton
David Oscier
David Oscier Royal Bournemouth Hospital
Paul A. Townsend
Paul A. Townsend University of Manchester
Freda K. Stevenson
Freda K. Stevenson University of Southampton
J. Sjef Verbeek
J. Sjef Verbeek Leiden University Medical Center
Andreas Strasser
Andreas Strasser Walter and Eliza Hall Institute of Medical Research
Christian Klein
Christian Klein Roche (Switzerland)

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